


Tryplog Injection
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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Product introduction
Tryplog Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Hot flashes, weakness, increased sweating, fatigue, back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Tryplog Injection
- Prostate cancer
- Endometriosis
- Precocious puberty (premature puberty)
Benefits of Tryplog Injection
Prostate cancer is a condition where cells in the prostate gland grow uncontrollably. Tryplog Injection helps by lowering certain hormones in the body that fuel the growth of prostate cancer cells. This slows disease progression and helps relieve related symptoms.
Endometriosis is a condition where tissue similar to the lining of the uterus grows outside it, causing pain and irregular periods. Tryplog Injection reduces hormone levels that trigger this growth, helping to lessen pain, bleeding, and other discomforts.
Precocious puberty is when children show signs of puberty earlier than normal. Tryplog Injection works by controlling the release of hormones responsible for early puberty, helping to delay development until the appropriate age and supporting healthy growth.
Side effects of Tryplog Injection
- Weakness
- Increased sweating
- Back pain
- Paresthesia (tingling or pricking sensation)
- Hot flashes
- Erectile dysfunction
How to use Tryplog Injection
How Tryplog Injection works
Quick tips
- Tryplog Injection helps in the treatment of locally advanced or metastatic prostate cancer.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
- It may also be used to treat endometriosis and precocious puberty (premature puberty).
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.

Kidney

Liver
Interaction with drugs
Amiodarone (Oral Route)
Amiodarone (Injection Route)
Artemether (Injection Route)
Artemether (Oral Route)
Disopyramide (Oral Route)
Frequently asked questions
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References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
- Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:
- Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:





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- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)















