Trofev 150mg Capsule

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 18 Mar 2026 | 02:05 PM (IST)

Trofev 150mg Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.

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Cold stored

Stored between 2-8°C

₹751 MRP ₹843.7511% off

Trofev 150mg Capsule is currently sold out

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Macdanib 150mg Capsule

₹692~~₹759.38~~

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Trofev 150mg Capsule

strip of 10 capsules

₹751

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Same composition

Macdanib 150mg Capsule

strip of 10 capsules

Nintedanib (150mg)

by Macleods Pharmaceuticals Pvt Ltd

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₹692

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General Information

Contains

Nintedanib (150mg)

Marketer

Hetero Healthcare Limited

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Trofev 150mg Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.

Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Trofev Capsule

Benefits of Trofev Capsule

Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Trofev 150mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

Treatment of Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Trofev 150mg Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Trofev Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trofev

Diarrhea
Nausea
Abnormal liver function tests
Loss of appetite
Headache
Weight loss
High blood pressure
Vomiting
Abdominal pain

How to use Trofev Capsule

Take this medicine in the dose and duration as advised by your doctor. Trofev 150mg Capsule should be taken with or after food.

How Trofev Capsule works

Trofev 150mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.

All substitutes for Trofev 150mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Macdanib 150mg Capsule

by Macleods Pharmaceuticals Pvt Ltd

₹69.2/capsule

8% cheaper

Fibronib 150 Capsule

by Chemo Healthcare Pvt Ltd

₹76.9/capsule

2% costlier

Quick tips

Take it with food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Trofev 150mg Capsule. Please consult your doctor.

Pregnancy

UNSAFE

Trofev 150mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Trofev 150mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Trofev 150mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Trofev 150mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
There is limited information available on the use of Trofev 150mg Capsule in these patients.

Liver

CAUTION

Trofev 150mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Please consult your doctor. Use of Trofev 150mg Capsule is not recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Trofev with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Carbamazepine (Oral Route)

Do not consume Nintedanib with Carbamazepine. Carbamazepine may reduce blood levels of Nintedanib.

Severe

Phenytoin (Oral Route)

Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.

Severe

Phenytoin (Injection Route)

Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.

Severe

Rifampicin (Oral Route)

Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.

Severe

Rifampicin (Injection Route)

Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.

Frequently asked questions

What is Trofev 150mg Capsule used for?

Trofev 150mg Capsule is a medication that helps slow down scarring or stiffness in the lungs. It is mainly used to treat conditions like pulmonary fibrosis (lung scarring) and certain types of lung diseases. It works by blocking substances in your body that cause lung tissues to become thick and stiff. Trofev 150mg Capsule helps slow down lung function decline, but it is not a cure.

Can Trofev 150mg Capsule cause serious health problems?

Yes, though rare, Trofev 150mg Capsule may cause liver injury, heart attack, bleeding problems, kidney issues (protein in urine) and gastrointestinal perforation. Your doctor will monitor you regularly to reduce these risks.

Is Trofev 150mg Capsule safe for people with liver or kidney problems?

Trofev 150mg Capsule is not recommended for moderate or severe liver disease. In mild cases, the dose is usually reduced. Trofev 150mg Capsule should also be used with caution in kidney impairment, and monitoring is essential.

Who should avoid taking Trofev 150mg Capsule?

Trofev 150mg Capsule should be avoided in individuals if they are pregnant or planning pregnancy, have severe liver problems, have had recent stomach surgery or are at high risk of bleeding or blood clots. There are no official contraindications, but caution is advised in these specific groups.

What should I do if I get diarrhea while on Trofev 150mg Capsule?

Diarrhea is common during Trofev 150mg Capsule treatment. Your doctor may advise using anti-diarrheal medicine early. Drink fluids and contact your doctor if it is severe or long-lasting, as they may adjust your dose.

Can Trofev 150mg Capsule reverse lung damage?

No, Trofev 150mg Capsule does not reverse fibrosis (lung scarring), but it slows its progression, helping to preserve lung function and potentially improve quality of life over time.

What foods should I avoid while taking Trofev 150mg Capsule?

While there are not specific foods you should avoid, eating a light meal when taking Trofev 150mg Capsule can help reduce stomach upset. If you experience diarrhea, avoid spicy, fatty, or junk foods that might make it worse.

How long does it take for Trofev 150mg Capsule to work?

Trofev 150mg Capsule works gradually to slow down lung scarring. It is not a quick-relief medication, and it may take several weeks or months before you notice improvements. Your doctor will monitor your progress through regular check-ups and tests.

When should I contact my doctor while taking Trofev 150mg Capsule?

Contact your doctor immediately if you experience severe diarrhea that does not improve, unusual bleeding or bruising, severe stomach pain, yellowing of skin or eyes, dark urine and fever with infection symptoms.

Fact Box

Chemical Class

Indolecarboxylic acids

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hetero Healthcare Limited
Address: S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Trofev 150mg Capsule

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Trofev Capsule

Benefits of Trofev Capsule

Side effects of Trofev Capsule

How to use Trofev Capsule

How Trofev Capsule works

All substitutes for Trofev 150mg Capsule

Macdanib 150mg Capsule

Fibronib 150 Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carbamazepine (Oral Route)

Phenytoin (Oral Route)

Phenytoin (Injection Route)

Rifampicin (Oral Route)

Rifampicin (Injection Route)

Frequently asked questions

What is Trofev 150mg Capsule used for?

Can Trofev 150mg Capsule cause serious health problems?

Is Trofev 150mg Capsule safe for people with liver or kidney problems?

Who should avoid taking Trofev 150mg Capsule?

What should I do if I get diarrhea while on Trofev 150mg Capsule?

Can Trofev 150mg Capsule reverse lung damage?

What foods should I avoid while taking Trofev 150mg Capsule?

How long does it take for Trofev 150mg Capsule to work?

When should I contact my doctor while taking Trofev 150mg Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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