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Last updated:
11 Nov 2019 | 01:58 PM (IST)
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Trendset M 500mg/20mg Tablet


Overview

Introduction

Trendset M 500mg/20mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.

Trendset M 500mg/20mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Uses of Trendset M Tablet

Side effects of Trendset M Tablet

Common
  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach upset
  • Headache
  • Nasal congestion
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Trendset M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trendset M 500mg/20mg Tablet is to be taken with food.

How Trendset M Tablet works

Trendset M 500mg/20mg Tablet is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Trendset M 500mg/20mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Trendset M 500mg/20mg Tablet during pregnancy is not available. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Trendset M 500mg/20mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Trendset M 500mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Trendset M 500mg/20mg Tablet may be needed. Please consult your doctor.
Use of Trendset M 500mg/20mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Trendset M 500mg/20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Trendset M 500mg/20mg Tablet may be needed. Please consult your doctor.
Trendset M 500mg/20mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Trendset M 500mg/20mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Patient Concerns

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Hi Doctor I have Type 2 diabetes, at present i m taking istamet 50/1000 mg, kindly advise if my medicine can be stopped
Dr. Shikha Mishra
Dietician
Please consult doctor regarding this issue
I was diagnosed with type 2 diabetes in January and I m taking medicine. Now it's under control. Can you suggest me a meal plan that I can go for to control my weight and diabetes. Thank you
Dr. Shikha Mishra
Dietician
eat 6-7 meals per day, which consist fruits, nuts, buttermilk,egg, homecooked food. Drink 3-4 litters of water.Be active whole day for personalized diet chart write to me on [email protected] do minimum 45 min exercise everyday like yoga, cardio or weights
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Do you have any questions related to Trendset M 500mg/20mg Tablet ?

User Feedback


FAQs

Q. What are the instructions for the storage and disposal of Trendset M?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Trendset M?

Trendset M is a combination of two medicines: Metformin and Teneligliptin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Teneligliptin inhibits the enzyme DP4 inhibitor and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Trendset M?

The use of Trendset M is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious, but rare side effect like lactic acidosis. On long-term use it can also lead to vitamin B12 deficiency.

Q. Are there any specific conditions in which Trendset M should not be taken?

The use of Trendset M should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Trendset M?

No, it is not safe to take Trendset M along with alcohol. It can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or hepatic impairment.

Q. Can the use of Trendset M cause hypoglycemia?

The use of Trendset M does not usually cause hypoglycemia (low blood sugar level). However, hypoglycemia may occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Trendset M lead to Vitamin B12 deficiency?

Yes, the use of Trendset M can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Capital Pharma, No 28, Lakshmipuram Main Road, Poombukar Nagar, Edayarpalayam, Coimbatore - 641038
Best Price
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