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Metformin + Teneligliptin

Information about Metformin + Teneligliptin

How Metformin + Teneligliptin works

Metformin + Teneligliptin is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Common side effects of Metformin + Teneligliptin

Diarrhea, Nausea, Vomiting, Hypoglycemia (low blood glucose level), Decreased appetite, Abdominal bloating, Flatulence, Constipation
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MD (Pharmacology), MBBS
Last updated
25 Jun 2020 | 09:15 AM (UTC)

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Available Medicine for Metformin + Teneligliptin

Zita-Met PlusGlenmark Pharmaceuticals Ltd
2632 variant(s)
Ziten-MGlenmark Pharmaceuticals Ltd
263 to ₹2882 variant(s)
Tendia MEris Lifesciences Ltd
130 to ₹2284 variant(s)
Dynaglipt-MMankind Pharma Ltd
109 to ₹1192 variant(s)
Tenglyn MZydus Cadila
204 to ₹2102 variant(s)
Tenepride MMicro Labs Ltd
144 to ₹2263 variant(s)
Afoglip MTorrent Pharmaceuticals Ltd
141 to ₹2674 variant(s)
T Glip-MIntas Pharmaceuticals Ltd
128 to ₹3366 variant(s)
Tenlimac MMacleods Pharmaceuticals Pvt Ltd
105 to ₹1774 variant(s)
Teneza-MTorrent Pharmaceuticals Ltd
155 to ₹2674 variant(s)

Expert advice for Metformin + Teneligliptin

  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metformin + Teneligliptin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Frequently asked questions for Metformin + Teneligliptin

Metformin + Teneligliptin

Q. Is it safe to use Metformin+Teneligliptin?

Yes, it is safe to use Metformin+Teneligliptin if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Metformin+Teneligliptin in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.

Q. Can the use of Metformin+Teneligliptin lead to hypoglycemia?

The use of Metformin+Teneligliptin does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Metformin+Teneligliptin cause nausea and vomiting?

Yes, the use of Metformin+Teneligliptin can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.

Q. Are there any specific contraindications associated with the use of Metformin+Teneligliptin?

The use of Metformin+Teneligliptin should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Can the use of Metformin+Teneligliptin cause lactic acidosis?

Yes, the use of Metformin+Teneligliptin can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Metformin+Teneligliptin and immediately consult your doctor.

Q. Can the use of Metformin+Teneligliptin lead to Vitamin B12 deficiency?

Yes, the use of Metformin+Teneligliptin can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.

Q. What is the storage condition for the Metformin+Teneligliptin?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.


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