Torisel Kit

Temsirolimus (25mg/ml)

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Prescription

required

Torisel Kit is used as a chemotherapy agent for the treatment of kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells). It works by blocking abnormal proteins that causes the multiplication of cancer cells. This helps in slowing the growth of tumors.

Written By Dr. Nitika Makhija, MDS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Aug 2025 | 01:41 PM (IST)

₹67680 MRP ₹743009% off

Gurgaon

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General Information

Contains

Temsirolimus (25mg/ml)

Marketer

Pfizer Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Torisel Kit is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

Some common side effects of this medicine include rash, weakness, nausea, edema, loss of appetite, anemia, increased glucose level in the blood, increased blood lipid level, and increased alkaline phosphatase level in blood. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, and swelling.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body.

Uses of Torisel Injection

Benefits of Torisel Injection

Treatment of Mantle-cell lymphoma
Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Torisel Kit helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Torisel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Torisel

Rash
Weakness
Nausea
Edema (swelling)
Decreased white blood cell count
Increased glucose level in blood
Anemia (low number of red blood cells)
Loss of appetite
Increased blood lipid level
Increased alkaline phosphatase level in blood

How to use Torisel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Torisel Injection works

Torisel Kit is a kinase inhibitor. It shows its action by blocking the action of the abnormal protein that causes the multiplication of cancer cells. This may help slow the growth of tumors.

Quick tips

Torisel Kit is given for the treatment of kidney cancer.
Torisel Kit interferes with wound healing, so it is advisable to use with caution if you have any scheduled surgery.
Inform your doctor if you have diabetes as the use of Torisel Kit might increase the level of blood sugar. Report excessive thirst or any increase in the volume or frequency of urination.
Report immediately for the occurrence of infections or any new or worsening abdominal pain or blood in their stools after using Torisel Kit.
Your doctor will monitor your cholesterol level as Torisel Kit might increase the level of serum triglycerides and cholesterol.
The use of live vaccines, and close contact with those who have received live vaccines, while on Torisel Kit should be avoided.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Torisel Kit. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Torisel Kit is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Torisel Kit is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Torisel Kit does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Torisel Kit is safe to use in patients with kidney disease. No dose adjustment of Torisel Kit is recommended.

Liver

CAUTION

Torisel Kit should be used with caution in patients with liver disease. Dose adjustment of Torisel Kit may be needed. Please consult your doctor.
Use of Torisel Kit is not advised in some patients with moderate to severe liver disease.

Interaction with drugs

Taking Torisel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Everolimus (Oral Route)

Concurrent use should be avoided.

Severe

Aprepitant (Oral Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.

Severe

Aprepitant (Injection Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.

Severe

Atazanavir (Oral Route)

Please consult with your doctor. If safer alternative of Temsirolimus is not available, your doctor may adjust the dose.

Severe

Bosentan (Oral Route)

Please consult with your doctor. If suitable alternative of Temsirolimus is not available, your doctor may adjust the dose. Bosentan may reduce blood levels of active form of Temsirolimus.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors

Related lab tests

Complete Blood Count

Cyclin D1

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1743-45.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1325.
Temsirolimus. Sandwich, Kent: Pfizer Limited; 2007 [revised Jan. 2019]. [Accessed 24 Jan. 2019] (online) Available from:
Temsirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc.; 2007 [revised Apr. 2007]. [Accessed 06 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Torisel Kit

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Torisel Injection

Benefits of Torisel Injection

Side effects of Torisel Injection

How to use Torisel Injection

How Torisel Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Everolimus (Oral Route)

Aprepitant (Oral Route)

Aprepitant (Injection Route)

Atazanavir (Oral Route)

Bosentan (Oral Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Cyclin D1

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests