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Composition FOR THYROX 12.5mcg tablet

Thyroxine(12.5mcg)

food interaction for THYROX tablet

alcohol interaction for THYROX tablet

pregnancy interaction for THYROX tablet

lactation interaction for THYROX tablet

food
alcohol
pregnancy
lactation
It is better to take Thyrox - 12.5 tablet empty stomach (1 hour before food or 2 hours after food).
Interaction with alcohol is unknown. Please consult your doctor.
Thyrox - 12.5 tablet is safe to use during pregnancy.
Adequate and well-controlled human studies have shown low or no risk.
SAFE
Thyrox - 12.5 tablet is probably safe to use during breastfeeding. Please consult your doctor.
SAFE

SALT INFORMATION FOR THYROX 12.5mcg tablet

Thyroxine(12.5mcg)

Thyrox tablet uses

Thyrox - 12.5 tablet is used in the treatment of hypothyroidism and myxedema coma.

How thyrox tablet works

Thyrox - 12.5 tablet is similar in structure to the hormone naturally produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce and relieves the symptoms of hypothyroidism ( tiredness, weight gain, and depression).

Common side effects of thyrox tablet

Anxiety, Vomiting, Diarrhoea, Palpitations, Nervousness, Weight loss, Tremor.

COMMON DOSAGE FOR THYROX - 12.5 TABLET

Patients taking THYROX - 12.5 TABLET

  • 94%
    Once A Day
  • 4%
    Twice A Week
  • 2%
    Twice A Day

SUBSTITUTES FOR THYROX tablet

10 Substitutes
10 Substitutes
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  • UTHYROX 12.5MCG TABLET
    (50 tablets in bottle)
    Merck Ltd
    Rs. 1.32/tablet
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    Rs. 66.15
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Top Endocrinologists

Expert advice FOR THYROX tablet

  • Thyroxine must be taken on an empty stomach. No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
  • You may have to wait for 6 to 8 weeks to get the full effect.
  • Your doctor may ask you to continue it lifelong. You must not stop taking it or change the dose, without speaking to your doctor first.
  • Dose adjustments are usually needed when starting the medicine and when your health changes.
  • Tell your doctor if you are pregnant or planning to get pregnant or breastfeeding.
  • Inform your doctor if you have heart disease. You may require a lesser dose of the medicine.
  • Inform your doctor if you get diarrhoea, nervousness, rapid pulse, insomnia, tremors, or chest pain could indicate severe toxicity and should prompt immediate medical attention. Your doctor may adjust the dose.

Frequently asked questions FOR THYROX 12.5mcg tablet

Thyroxine

Q. Is Thyroxine a beta blocker?
No. Thyroxine is not a beta-blocker. It is a hormone synthesised by the thyroid gland present in the neck region. It maintains normal growth & development, body temperature & energy levels.
Q. Is Thyroxine a blood thinner?
No. Thyroxine is not a blood thinner. It is a hormone used for the treatment of hypothyroidism (decreased thyroid hormone). Blood thinners are medicines which prevent abnormal clot formation.
Q. What is the dose for Thyroxine?
The dose is individualised on the basis of clinical response and biochemical tests. Regular monitoring of thyroid stimulating hormone (TSH) and thyroxine is recommended when starting therapy or changing the dose. Do not change the dose or stop the medicine without consulting your doctor.
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Q. Is Thyroxine a growth hormone?
No. Thyroxine is a hormone synthesised by the thyroid gland present in the neck region. Growth Hormone, on the other hand, is secreted by the pituitary gland present in the brain. Thyroxine is required for the proper functioning of growth hormone.
Q. Is Thyroxine a neurotransmitter?
No. Thyroxine is not a neurotransmitter. Thyroxine is a hormone secreted directly into the blood by the thyroid gland. The blood then takes it to the target organs in the body. A neurotransmitter, on the other hand, transmits impulses from one nerve cell to the other in the brain.
Q. Is Thyroxine a tropic hormone?
Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the pituitary gland in the brain. The thyroid gland secretes thyroxine, which targets the hypothalamus and therefore can be considered a tropic hormone.
Q. Is Thyroxine a protein?
No. Thyroxine is not a protein. The normal thyroid gland secretes two thyroid hormones - triiodothyronine (T3) and tetraiodothyronine (T4 or thyroxine). More than 99% of these hormone circulating in the blood as bound to carrier proteins, thyroxine-binding globulin, synthesised in the liver.
Q. Is Thyroxine a peptide or steroid?
Thyroxine is neither a peptide nor a steroid. Thyroxine hormone is an amino acid (tyrosine) derived hormone. (Amino acids are tiny building blocks of proteins, but they cannot be called proteins by themselves unless a number of them are connected in a sequence).
Q. Does Thyroxine cause weight loss?
Yes. Thyroxine can produce side effect as weight loss. It is usually due to excessive dose. However, it should not be used for treat obesity.
Q. Can Thyroxine be used as hormone replacement therapy?
Yes. Thyroxine can be used as a hormone replacement therapy to compensate the deficiency of thyroid hormone in the body.
Q. Is Thyroxine a peptide hormone?
No. Thyroxine is an amino acid derieved hormone.
Q. Is Thyroxine a hormone?
Yes. Thyroxine is a hormone secreted from the thyroid gland. It causes increased oxygen consumption by most tissues of the body, increases the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins.
Q. Is Thyroxine a slowly acting drug?
Yes. Thyroxine is a slow-acting drug. It acts through receptors situated in the nucleus and results in a formation of various protein to target its action hence thyroxine takes a time to act.
Q. Is Thyroxine a diuretic?
No. Thyroxine is not a diuretic. It is a hormone secreted by the thyroid gland.
Q. Which organ does Thyroxine target?
Thyroxine targets all the cells in the body and helps in metabolism. It is also required for normal growth and development of the body.
Q. Which organ secretes Thyroxine and triiodothyronine?
The thyroid gland located in the neck secrete thyroid hormones (thyroxine and triiodothyronine).
Q. Which foods contain Thyroxine?
Foods which contains Thyroxine are green vegetables, sea fishes and seafoods.
Q. When is Thyroxine released into the blood?
When Thyroxine levels are low in the blood, the brain senses the signal and releases hormones (thyroid releasing hormone) to stimulate the thyroid gland to secrete thyroxine which is released into the blood.
Q. When does Thyroxine stop working?
If thyroxine is taken with food or even just before food the absorption of the thyroxine from the intestine decreases from the intestine and hence the desired effects are not seen. Similarly, if the dose of the thyroxine given is lesser than what is required by the body then it might not work.
Q. Why is Thyroxine taken in the morning?
Thyroxine absorption is maximum when taken in empty stomach and the absorption significantly decreases when taken with food, coffee or tea. So it is advised to take thyroxine in empty stomach in the morning.
Q. What are the storage conditions for Thyroxine?
It should be stored temperature range of 15°-30°C (59°-86°F).
Q. Why Thyroxine increase metabolic rate?
Thyroxine controls the basal metabolic rate of an individual. It increases the oxygen consumption and rates of ATP hydrolysis by increasing metabolism of carbohydrates and fats. It also increases the respiration and leads to heat generation.
Q. What is Thyroxine poisoning?
Thyroxine poisoning occur if an excessive dose is taken. It present as a headache, hyperactivity, nervousness, anxiety, irritability, heat intolerance, fever, excessive sweating, palpitations, tachycardia, arrhythmias, increased pulse and blood pressure. Inform your doctor as soon as possible.
Q. Why is Thyroxine called personality hormone?
Thyroxine is responsible for the metabolism of carbohydrate, fats and proteins which maintain the basal metabolic rate and normal growth and development of the body. Thyroid hormone is also responsible for the growth of bones and nerve cells. As the growth of the body is dependent on the thyroid hormone so it is called the personality hormone.
Q. Why is Thyroxine called calorigenic hormone?
Thyroxine is called as a calorigenic hormone because it increases oxygen consumption by most tissues of the body, increases the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins.
Q. How quickly does Thyroxine work?
Thyroxine is a slow acting hormone and due to the long half-life of levothyroxine, the peak therapeutic effect at a given dose of levothyroxine can only be seen after 4-6 weeks.
Q. How thyroxine modulate erythropoiesis?
Thyroxine is required for the normal functioning of the body. Research has shown that thyroid hormone significantly affects the erythropoiesis and increases red blood cell synthesis. Thyroxine is not approved to treat anemia (decreased red cell count).
Q. How are Thyroxine levels measured?
Thyroid stimulating hormone (TSH) is used as the main guide to dosing Thyroxine. It is elevated due to loss of negative feedback of T4 on the pituitary. With adequate Thyroxine replacement, TSH should return to normal or low-normal concentration. Thyroxine blood level is not measured as a guide to dosing of Thyroxine.
Q. Where are Thyroxine receptors located?
The receptors for Thyroxine are located in the nucleus. It goes and binds to them and leads to various changes in the synthesis of proteins and signalling molecules.
Q. Is thyroid medication Gluten Free?
Yes. Thyroid medication is gluten free.
Q. Are Thyroxine and Levothyroxine the same?
No. Thyroxine is a hormone which is produced naturally by the thyroid gland. Levothyroxine is a synthetic form of thyroxine which is used as a medication to treat hypothyroidism.
Q. How long can a body survive without Thyroxine?
There are no such reports of how long a body survives but Thyroxine is an essential hormone for maintaining the metabolism, growth and development of the body and its deficiency leads to hypothyroidism which if left untreated can lead to severe disease.
Q. When is Thyroxine used along with carbimazole?
Thyroxine is used with carbimazole in the treatment of Graves disease or hyperthyroidism. Studies have shown it is used as block–replace regimen which means the option of maintaining the high dose of antithyroid drugs along with adding levothyroxine to maintain normal thyroid state.
Q. Can I take an antidepressant along with Thyroxine?
No. There are noted interactions between Thyroxine and few antidepressants which lead to increased adverse effects of both the drugs so consult your doctor and do inform him before prescribing any of the medication.
Q. What is the effect of grapefruit juice on the absorption of Thyroxine?
Grapefruit juice slightly decreases the absorption of levothyroxine when taken together otherwise there is no major interaction between these two.
Q. Can I take thyroxine with tea?
No. Thyroxine cannot be taken with tea. Though major interactions are not noted when taken with together the absorption of the thyroxine from the intestine decreases and hence the desired effects are not achieved.
Q. Can I take vitamins with Thyroxine and what it's effect?
Yes. Vitamins can be added to your diet and can be taken with levothyroxine, but you should not take vitamin supplement within four hours of taking your thyroid medication.
Q. Can I take omeprazole along with Thyroxine?
No. Omeprazole should not be taken with Thyroxine. Omeprazole increases the gastric pH and interferes with the absorption of the Thyroxine.
Q. What is the effect of iodine while I take thyroxine?
Iodine, when given with Thyroxine, may increase thyroid hormone secretion, which may result in hyperthyroidism. Hyperthyroidism may develop over several weeks and may persist for several months after therapy discontinuation.
Q. Can I take Thyroxine with iron tablets?
No. Thyroxine should not be taken with the iron tablet. The absorption of Thyroxine is decreased when taken together. You should take them with a gap of 4 hours between them.
Q. Which is the correct way to take Thyroxine, with or without food and why?
If thyroxine is taken with food or even just before food the absorption of the Thyroxine from the intestine decreases and hence the desired effects are not seen. So thyroxine should always be taken in empty stomach preferably one-half to one-hour before breakfast.
Q. Can I take Thyroxine with milk?
No. Thyroxine should not be taken with milk. The absorption of Thyroxine is decreased when taken with milk. It should be taken 1 hour before and 2 hours after taking milk.
Q. Can I take Thyroxine with calcium?
No. Thyroxine should not be taken with calcium. The absorption of Thyroxine is decreased when taken with calcium. You should take them with a gap of 4 hours between them.
Q. Can I take Thyroxine with coffee?
No. Thyroxine should not be taken with coffee. The absorption of thyroxine is decreased when taken with coffee. It should be taken 1 hour before and 2 hours after taking coffee.
Q. Can I take Thyroxine with food?
No. Thyroxine should not be taken with food. The absorption of Thyroxine is decreased when taken with food. It should be taken 1 hour before and 2 hours after taking food.
Q. Can Thyroxine used in the treatment obesity?
No. Thyroxine should not be used to treat obesity. It can cause weight loss as a side effect but it should not be used for the treatment of obesity as it can cause serious life-threatening side effects if given with other weight reducing medications.
Q. Can Thyroxine be used in the treatment of depression?
No. Thyroxine is not approved for use in depression. But some of the research studies have shown that adding Thyroxine to the antidepressant medication therapy has increased the effectiveness of antidepressant therapy in the patients.
Q. Can Thyroxine help you get pregnant?
Thyroxine treats hypothyroidism (decreased thyroid hormone) and associated complications leading to increases chances of conceiving. Consult your doctor before starting thyroxine as failure to conceive is not merely due to decreased thyroid hormone but due to several other factors. Always start the medicine consulting with the doctor.
Q. Should I take Thyroxine in morning or evening?
It is preferred to take Thyroxine in morning on empty stomach. Research has shown that even if it is given in the evening, it shows the same effects as compared to morning. It is not practised because of ensuring an empty stomach by the patient.
Q. Should I take Thyroxine if I have a cardiac disease?
Yes. Thyroxine can be used but at a lower dose or given on an alternate day. There are high chances of side effects in a person with the cardiac disease like an increase in heart rate, cardiac wall thickness, and cardiac contractility and it may precipitate angina or irregular heart rhythms. Inform your doctor if you have heart disease. You may adjust the dose.
Q. What are the serious side effects of Thyroxine?
The serious side effects of Thyroxine are usually due to excessive doses, so symptoms are similar to hyperthyroidism. It may cause diarrhoea, vomiting, weight loss with increased appetite, palpitations, angina, insomnia and restlessness. Inform your doctor if you have these symptoms.
Q. Can I take antacids with Thyroxine?
No. Thyroxine should not be taken with an antacid. The absorption of Thyroxine is decreased when taken together. You should take them with a gap of 4 hours between them.
Q. When should I get thyroid function test (TSH) after starting Thyroxine?
Thyroid function test should be measured three months after starting treatment or change in dose.
Q. Can Thyroxine be taken along with MAO inhibitor?
Yes. Thyroxine can be taken with MAO inhibitors. Consult your doctor before starting these medications.

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Content on this page was last updated on 10 June, 2017, by Dr. Varun Gupta (MD Pharmacology)