Thalide 50mg Capsule

Thalidomide (50mg)

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Thalide 50mg Capsule is used in the treatment of multiple myeloma and lepra reaction. This medicine belongs to a group of medicines which affect how your immune system works.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 14 Apr 2026 | 04:21 PM (IST)

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General Information

Contains

Thalidomide (50mg)

Marketer

United Biotech Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Thalide 50mg Capsule should be taken in the exact dose and duration recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Before taking Thalide 50mg Capsule inform your doctor if you are suffering from any heart disease. Your doctor may get regular blood tests to check number of blood cells during your treatment. It may reduce white blood cells thereby, increasing the susceptibility to infections.

Common side effects of this medicine include nausea, rash, breathlessness, dizziness, edema (swelling), fatigue, and confusion. Let your doctor know if any of these side effects bothers you or get worse. They may be able to suggest ways to treat or prevent them. You should not drive or operate machinery as Thalide 50mg Capsule may makes you feel sleepy. Women or men who are undergoing treatment should use effective contraception method and avoid pregnancy till doctor recommends it.

Uses of Thalide Capsule

Multiple myeloma
Lepra reaction

Benefits of Thalide Capsule

Lepra reaction
Lepra reactions are complicated inflammatory reactions that may occur before, during or after the treatment for leprosy, a serious bacterial skin disease. These reactions increase nerve damage and worsen disability in leprosy patients. Therefore lepra reactions need treatment with medicines such as Thalide 50mg Capsule in order to stimulate the immune system and aid in recovery. This medicine will also prevent further damage due to lepra reactions. Take it as prescribed by the doctor to get the most benefit.

Side effects of Thalide Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Thalide

Nausea
Rash
Breathlessness
Dizziness
Edema (swelling)
Fatigue
Muscle weakness
Anxiety
Confusion
Constipation
Tremors
Sensory neuropathy
Change in body weight
Thromboembolism
Muscle pain
Anaphylactic reaction
Decreased potassium level in blood
Headache
Sleepiness

How to use Thalide Capsule

Take this medicine in the dose and duration as advised by your doctor. Thalide 50mg Capsule is to be taken on an empty stomach.

How Thalide Capsule works

Thalide 50mg Capsule modulates the activity of body's immune system and helps indirectly attacking the cancer cells. It also stops the growth of blood vessels in cancer.

All substitutes for Thalide 50mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Thalide 50mg Capsule should be taken on an empty stomach, try to take it at same time every day.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Do not donate blood during or after 7 days of the treatment with this medicine.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Thalide 50mg Capsule may cause excessive drowsiness when taken with alcohol.

Pregnancy

UNSAFE

Thalide 50mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Thalide 50mg Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Thalide 50mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
You may experience side effects, such as dizziness, tiredness, sleepiness or blurred vision with Thalide 50mg Capsule and this may affect your ability to drive.

Kidney

CAUTION

Thalide 50mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Thalide 50mg Capsule in patients with liver disease.

Interaction with drugs

Taking Thalide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Pegylated Interferon Alpha 2A (Injection Route)

Your doctor may monitor your blood cell count frequently and adjust the doses as per the observations.

Moderate

Zoledronic acid (Injection Route)

If concurrent use is essential, your doctor may monitor kidney function and other treatment outcome and may modify the treatment protocol as per the observation.

Moderate

Dienogest (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Dehydroepiandrosterone (Micronized) (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Acrivastine (Oral Route)

If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

What is Thalide 50mg Capsule used for?

Thalide 50mg Capsule is used to treat multiple myeloma, a type of blood cancer. It is also used to treat moderate to severe skin lesions caused by leprosy (erythema nodosum leprosum).

Can Thalide 50mg Capsule cause birth defects?

Yes, Thalide 50mg Capsule can cause severe birth defects or death of an unborn baby. Even a single dose during pregnancy can be dangerous. Women must use two reliable forms of birth control before, during, and after treatment, and undergo frequent pregnancy testing.

Is Thalide 50mg Capsule safe for use in women who are pregnant or may become pregnant?

No, Thalide 50mg Capsule must never be used during pregnancy. Women of childbearing potential must follow strict pregnancy prevention programs and avoid pregnancy for at least four weeks before starting and four weeks after stopping the medicine.

What are the serious side effects of Thalide 50mg Capsule?

Serious side effects of Thalide 50mg Capsule include severe blood clots, nerve damage (peripheral neuropathy), low white blood cell count, liver problems, and serious skin rashes such as Stevens-Johnson Syndrome. Medical help should be sought immediately if any of these occur.

Who should not take Thalide 50mg Capsule?

Individuals should not take Thalide 50mg Capsule if they are pregnant, breastfeeding, or unable to follow the birth control requirements. People allergic to Thalide 50mg Capsule or who have had serious blood clots or nerve damage should consult a doctor before use.

What precautions should be taken to avoid nerve damage from Thalide 50mg Capsule?

Patients should be regularly monitored for numbness, tingling, or pain in the hands and feet during Thalide 50mg Capsule treatment. If signs of nerve damage appear, the doctor may reduce the dose or stop the medicine to prevent permanent nerve problems.

Fact Box

Chemical Class

Phthalimides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Thalidomide & Its Immunomodulatory Derivatives (IMiDs)

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1740-42.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 973-74.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1342-50.
Thalidomide. Stockley Park, Uxbridge: Celgene Ltd.; 2008 [revised 8 Aug. 2018]. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Thalidomide [Prescribing Information]. Summit, NJ: Celgene Corporation; 2014. [Accessed 28 Mar. 2023] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Thalide 50mg Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Thalide Capsule

Benefits of Thalide Capsule

Side effects of Thalide Capsule

How to use Thalide Capsule

How Thalide Capsule works

All substitutes for Thalide 50mg Capsule

THalix 50 Capsule

Thycad 50mg Capsule

Redemide 50mg Capsule

Adthal 50 Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegylated Interferon Alpha 2A (Injection Route)

Zoledronic acid (Injection Route)

Dienogest (Oral Route)

Dehydroepiandrosterone (Micronized) (Oral Route)

Acrivastine (Oral Route)

Frequently asked questions

What is Thalide 50mg Capsule used for?

Can Thalide 50mg Capsule cause birth defects?

Is Thalide 50mg Capsule safe for use in women who are pregnant or may become pregnant?

What are the serious side effects of Thalide 50mg Capsule?

Who should not take Thalide 50mg Capsule?

What precautions should be taken to avoid nerve damage from Thalide 50mg Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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