Tepmetko 225mg Tablet

Tepotinib (225mg)

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Tepmetko 225mg Tablet is used to treat advanced non-small cell lung cancer in adult patients. It is used in patients in whom the cancer has either spread to other parts of the body or cannot be removed by surgery and previous treatment has not helped to stop the cancer.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 06 Aug 2026 | 01:09 AM (IST)

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General Information

Contains

Tepotinib (225mg)

Marketer

Merck Ltd

The content is shown in English

Product introduction

Tepmetko 225mg Tablet helps by slowing or stopping the cancer from growing. Tepmetko 225mg Tablet should be taken with food and swallowed as a whole. Do not crush or chew the tablet. The dose and duration of the treatment will depend on your condition and how well you respond to it. However, take it for as long as your doctor has prescribed. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless the doctor tells you to.

The most common side effects of Tepmetko 225mg Tablet include peripheral edema, nausea, hypoalbuminemia, diarrhea, and an increase in creatinine. If any of these side effects bother you, let your doctor know. They may also advise regular monitoring of liver function while you are taking this medicine.

Many other medicines can affect or be affected by this medicine, so let your doctor know about all the other medicines that you are using. Tepmetko 225mg Tablet is not recommended during pregnancy or while breastfeeding. Hence, it is important for both males and females of reproductive age to use effective contraception to avoid pregnancy during the treatment with this medicine.

Uses of Tepmetko Tablet

Treatment of Non-small cell lung cancer

Benefits of Tepmetko Tablet

Treatment of Non-small cell lung cancer
Tepmetko 225mg Tablet is used to treat a certain type of non-small cell lung cancer that has spread to other body parts in adults.

Side effects of Tepmetko Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tepmetko

Peripheral edema
Nausea
Low albumin level in blood
Diarrhea
Increased creatinine level in blood

How to use Tepmetko Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tepmetko 225mg Tablet should be taken with or after food.

How Tepmetko Tablet works

Tepmetko 225mg Tablet works by blocking the action of certain abnormal proteins that signal cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Quick tips

Women of childbearing potential should use effective contraception during the treatment and for at least 1 week after the last dose of Tepmetko 225mg Tablet.
To reduce nausea, take anti-nausea medications as prescribed by your doctor and eat small, frequent meals.
Swelling of the hands or feet is a common side effect of Tepmetko 225mg Tablet. Your doctor may suggest leg elevation or dietary salt modification to ease the symptoms of swelling.
Drink at least 7-8 large glasses of water every 24 hours, unless you are instructed otherwise.
Tepmetko 225mg Tablet is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Tepmetko 225mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Tepmetko 225mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CAUTION

Tepmetko 225mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Tepmetko 225mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Tepmetko 225mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Tepmetko 225mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Tepmetko with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Everolimus (Oral Route)

Do not consume Tepotinib with Everolimus. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Everolimus.

Severe

Fexofenadine (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.

Severe

Fexofenadine (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.

Severe

Fexofenadine (Oral Route)

Do not consume Tepotinib with Fexofenadine. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Fexofenadine.

Severe

Indinavir (Oral Route)

Do not consume Tepotinib with Indinavir. Indinavir may raise blood levels of Tepotinib.

Fact Box

Chemical Class

Quinoline derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Merck Ltd
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Vendor Details

Country of origin: Germany
A licensed vendor partner from your nearest location will deliver Tepmetko 225mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Tepmetko 225mg Tablet

Tepmetko 225mg Tablet

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General Information

Contains

Marketer

Product introduction

Uses of Tepmetko Tablet

Benefits of Tepmetko Tablet

Side effects of Tepmetko Tablet

How to use Tepmetko Tablet

How Tepmetko Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Everolimus (Oral Route)

Fexofenadine (Oral Route)

Fexofenadine (Oral Route)

Fexofenadine (Oral Route)

Indinavir (Oral Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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