Temokem 100mg Injection
Prescription Required
Product introduction
Temokem 100mg Injection is used in the treatment of a specific type of brain cancer. It is used to treat brain tumors if they return or get worse after standard treatment. It may be also used to treat other conditions, as determined by the doctor.
Temokem 100mg Injection is given by a nurse or a doctor. You should not self-administer this medicine. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on the severity of your condition and may change from time to time. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, constipation, headache, and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver, and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Temokem 100mg Injection is given by a nurse or a doctor. You should not self-administer this medicine. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on the severity of your condition and may change from time to time. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, constipation, headache, and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver, and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Temokem Injection
Benefits of Temokem Injection
In Brain tumor
Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Temokem 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Temokem Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Temokem
- Memory loss
- Rash
- Headache
- Dizziness
- Convulsion
- Coordination disorder
- Insomnia (difficulty in sleeping)
- Vomiting
- Weakness
- Nausea
- Loss of appetite
- Hair loss
- Fatigue
- Fever
- Diarrhea
- Constipation
- Hemiparesis (weakness on one side of the body)
- Viral infection
How to use Temokem Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Temokem Injection works
Temokem 100mg Injection is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Temokem 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Temokem 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Temokem 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Temokem 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Temokem 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Temokem 100mg Injection may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking Temokem 100mg Injection.
Cautious use is advised in patients with severe kidney disease while they are taking Temokem 100mg Injection.
Liver
CAUTION
Temokem 100mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Temokem 100mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Temokem 100mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Temokem 100mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Temokem Injection?
If you miss a dose of Temokem 100mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Temokem 100mg Injection
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Quick tips
- Temokem 100mg Injection is given as an injection into the vein under the supervision of a doctor only.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
- Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
- Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.
Fact Box
Chemical Class
Dacarbazine Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent
Interaction with drugs
Taking Temokem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Temozolomide from 1 day before until 1 day after taking Molgramostim.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Temozolomide from 14 days before until 24 days after taking Pegfilgras
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Temozolomide from 1 day before until 1 day after taking Sargramostim.
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Temozolomide.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
- Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
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