Temozolomide

Information about Temozolomide

Temozolomide Uses

Temozolomide is used in the treatment of brain tumor.

How Temozolomide works

Temozolomide is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Common side effects of Temozolomide

Nausea, Vomiting, Constipation, Headache, Fatigue, Convulsion, Coordination disorder, Diarrhea, Dizziness, Fever, Hair loss, Hemiparesis (weakness on one side of the body), Insomnia (difficulty in sleeping), Loss of appetite, Memory loss, Rash, Viral infection, Weakness
CONTENT DETAILS
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
23 Mar 2020 | 11:26 AM (UTC)
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Available Medicine for Temozolomide

GliozDr Reddy's Laboratories Ltd
2386 to ₹254423 variant(s)
TemonatNatco Pharma Ltd
6300 to ₹237953 variant(s)
NublastZydus Cadila
2100 to ₹180003 variant(s)
TemodalFulford India Ltd
2905 to ₹228283 variant(s)
TemolonCelon Laboratories Ltd
1809 to ₹206253 variant(s)
TemoteroHetero Drugs Ltd
1779 to ₹202473 variant(s)
TemosideCipla Ltd
539 to ₹56253 variant(s)
TemotrustPanacea Biotec Ltd
1970 to ₹213233 variant(s)
GliotemSun Pharmaceutical Industries Ltd
439 to ₹47093 variant(s)
GlistromaAlkem Laboratories Ltd
2534 to ₹197153 variant(s)

Expert advice for Temozolomide

  • Temozolomide should be taken on an empty stomach.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
  • Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.

Frequently asked questions for Temozolomide

Temozolomide

Q. What is Temozolomide used for/ what does Temozolomide treat/ Is Temozolomide chemotherapy/ is Temozolomide cytotoxic/ is Temozolomide a radiosensitizer?

Temozolomide is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer

Q. Is Temozolomide effective/ does Temozolomide work?

Temozolomide is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor

Q. How is Temozolomide given/administered/ metabolized/ how long does Temozolomide stay in the body?

Temozolomide is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours

Q. How does Temozolomide cross the blood-brain barrier?

Temozolomide because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid

Q. Does Temozolomide cause hair loss?

Hair loss is a side effect of using Temozolomide. Always follow doctor's advice regarding its use

Q. Is Temozolomide FDA approved?

Temozolomide is a FDA approved drug.

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