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Tagrisso 80mg Tablet

Osimertinib (80mg)
Genuine
Authenticity Assured
Prescription
required
Tagrisso 80mg Tablet is a protein kinase inhibitor used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain estimated glomerular filtration rate (EGFR) mutations.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Apr 2026 | 03:57 PM (IST)
₹124934
₹138830.83
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10 tablets
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General Information

The content is shown in English
Tagrisso 80mg Tablet image
Tagrisso 80mg Tablet image
Tagrisso 80mg Tablet image
Tagrisso 80mg Tablet image

Product introduction

Tagrisso 80mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea is a very common side effect of this medicine, so drink plenty of fluids. Other common side effects of this medicine are dry skin, anemia, fatigue, musculoskeletal pain, and rash. You must have to inform your doctor if you experience difficulty in breathing along with fever and cough, or severe peeling of the skin. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby increasing your susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Tagrisso Tablet

Benefits of Tagrisso Tablet

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Tagrisso 80mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Tagrisso Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tagrisso
  • Decreased white blood cell count (lymphocytes)
  • Lymphopenia
  • Diarrhea
  • Rash
  • Decreased white blood cell count (neutrophils)
  • Stomatitis (Inflammation of the mouth)

How to use Tagrisso Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tagrisso 80mg Tablet may be taken with or without food.

How Tagrisso Tablet works

Tagrisso 80mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Quick tips

  • Take Tagrisso 80mg Tablet at the same time every day, with or without food, to maintain steady levels of medicine in your body.
  • Swallow the medicine whole and do not crush or split it, unless your doctor tells you otherwise.
  • Let your doctor know right away if you develop shortness of breath, chest pain, or a cough that worsens.
  • Avoid grapefruit and grapefruit juice, as they can affect how the medicine works in your body.
  • Do not skip routine heart and lung checks, as Tagrisso 80mg Tablet may affect both over time.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tagrisso 80mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Tagrisso 80mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Tagrisso 80mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Tagrisso 80mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Tagrisso 80mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Tagrisso 80mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Tagrisso with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Fluconazole (Oral Route)

Do not consume Fluconazole with Osimertinib.
Life-threatening

Tetrabenazine (Oral Route)

Do not consume Tetrabenazine with Osimertinib.
Life-threatening

Fluconazole (Injection Route)

Do not consume Fluconazole with Osimertinib.
Life-threatening

Hydroxychloroquine (Oral Route)

Do not consume Hydroxychloroquine with Osimertinib.
Life-threatening

Sevoflurane (Oral Route)

Do not consume Sevoflurane with Osimertinib.

Frequently asked questions

Tagrisso 80mg Tablet is a targeted cancer medication used to treat non-small cell lung cancer (NSCLC). It is prescribed when the cancer has a specific genetic change (EGFR mutation) and has either spread to other parts of the body or cannot be removed by surgery. It works by blocking signals that make cancer cells grow and spread.
Yes, Tagrisso 80mg Tablet can affect your heart function. Your doctor will check your heart health before and during treatment. Tell your doctor right away if you notice a fast or irregular heartbeat, dizziness, shortness of breath, chest pain, or fainting.
Your doctor will schedule regular scans and tests to check how well the treatment is working. You may also notice improvements in symptoms like breathing or coughing. However, everyone responds differently to treatment, so regular check-ups are important.
The serious side effects of Tagrisso 80mg Tablet include lung inflammation (ILD or pneumonitis), heart failure (cardiomyopathy), QTc prolongation (irregular heartbeat), severe skin reactions, and aplastic anemia (bone marrow failure).
There are no absolute contraindications of Tagrisso 80mg Tablet listed, but it should be used cautiously in patients with heart problems, liver disease, and severe infections. Always tell your doctor about any medical history.
While taking Tagrisso 80mg Tablet, avoid St. John's Wort supplements, strong CYP3A4 inducer drugs, other QT-prolonging drugs, etc., and check with your doctor before taking any new medications. You should protect your skin from the sun and avoid activities that might cause injury, as the medication can slow wound healing.
Contact your doctor right away if you experience severe breathing problems or shortness of breath, fever with cough and chest pain, severe skin reactions or blistering, heart symptoms (irregular heartbeat, chest pain), eye problems or vision changes, etc.
Tagrisso 80mg Tablet does not cure lung cancer but is highly effective at slowing the disease, improving survival, and shrinking tumors in patients with specific EGFR mutations.

Fact Box

Chemical Class

N- alkylindoles

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)
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User feedback

Once A Day
100%
Non-small cell lung cancer
94%
Others
6%
Average
58%
Excellent
21%
Poor
21%
No Side Effect
67%
Diarrhea
17%
Rash
17%
With or without food
60%
With food
40%
Expensive
67%
Not Expensive
20%
Average
13%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: Sweden
A licensed vendor partner from your nearest location will deliver Tagrisso 80mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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