Succin Injection

Suxamethonium (NA)

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Succin Injection belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)

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General Information

Contains

Suxamethonium (NA)

Marketer

Harson Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Succin Injection is administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include stomach pressure, excessive salivation, muscle twitching, and postoperative muscle pain. Other common side effects include increased intraocular pressure, slow heart rate, increased heart rate, flushing of the skin, high blood pressure, low blood pressure, rash, and increased potassium level in blood. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, to make sure it is safe for you, you should let your doctor know if you have any other medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Succin Injection

Skeletal muscle relaxation during surgery

Benefits of Succin Injection

Skeletal muscle relaxation during surgery
Succin Injection is used to relax muscles during anesthesia and surgical procedures. It works by blocking chemical messengers in the brain that are responsible for rigidity, inflammation, or swelling. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Succin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Succin

Excessive salivation
Muscle twitching
Postoperative muscle pain
Increased intraocular pressure
Slow heart rate
Increased heart rate
Flushing of skin
High blood pressure
Hypotension (low blood pressure)
Rash
Increased potassium level in blood

How to use Succin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Succin Injection works

Succin Injection relaxes the muscles by blocking the impulses from the nerves.

Quick tips

Succin Injection is given as an injection into vein under the supervision of a doctor.
It makes you feel dizzy or drowsy. Do not drive until you know how Succin Injection affects you.
Your doctor will monitor your blood pressure regularly as the medicine may lead to high blood pressure.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Succin Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Succin Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Succin Injection during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Succin Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Succin Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Succin Injection is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Succin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Digoxin (Oral Route)

If concurrent use is essential, watch out for symptoms such as fatigue, irregular heart rates, agitation, anxiety, or breathlessness, and consult your doctor if you experience them. They may monitor your ECG closely.

Moderate

Fentanyl (Injection Route)

You should be prepared for a longer than usual recovery time. Suxamethonium may raise blood levels of the active form of Fentanyl.

Moderate

Fentanyl (Transdermal Route)

You should be prepared for a longer than usual recovery time. Suxamethonium may raise blood levels of the active form of Fentanyl.

Moderate

Thalidomide (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations.

Moderate

Amikacin (Injection Route)

Your muscles may remain relaxed or weak for a longer than usual time.

Frequently asked questions

Why does Succin Injection cause bradycardia (abnormally slow heart beat)?

The initial metabolite of Succin Injection produces a transient negative chronotropic effect through its stimulation of sinus node muscarinic receptors. Repeated dosing or infusions of Succin Injection may lead to bradycardia that is appropriately treated with atropine

Why does Succin Injection cause fasciculation (twitching of muscles under the skin)?

Succin Injection cause fasciculation by an action on some distal part of motor nerve fibres

Is Succin Injection still used?

Succin Injection is still used during general anesthesia

Is Succin Injection reversible?

Succin Injection is a short-acting muscle relaxant which exerts a depolarizing effect at the neuromuscular junction. This effect is not reversible pharmacologically

Is Succin Injection is contraindicated in burned patients?

Yes, Succin Injection should not be used in burned patients

Does Succin Injection cross the placenta?

In normal therapeutic doses, Succin Injection does not cross the placental barrier in sufficient amounts.

Fact Box

Chemical Class

Acyl cholines

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Peripherally Acting Skeletal Muscle Relaxants

References

Suxamethonium. Co Dublin, Ireland: Mercury Pharma International Ltd.; 1990 [revised Jul. 2018]. [Accessed 02 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Harson Laboratories
Address: 12, R. C. Patel Industrial Estate, Akota, Baroda - 390 020., INDIA

Vendor Details

Country of origin: India

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Succin Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Succin Injection

Benefits of Succin Injection

Side effects of Succin Injection

How to use Succin Injection

How Succin Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Digoxin (Oral Route)

Fentanyl (Injection Route)

Fentanyl (Transdermal Route)

Thalidomide (Oral Route)

Amikacin (Injection Route)

Frequently asked questions

Why does Succin Injection cause bradycardia (abnormally slow heart beat)?

Why does Succin Injection cause fasciculation (twitching of muscles under the skin)?

Is Succin Injection still used?

Is Succin Injection reversible?

Is Succin Injection is contraindicated in burned patients?

Does Succin Injection cross the placenta?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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