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Staphonex 500mg Injection

Flucloxacillin Sodium (500mg)

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Staphonex 500mg Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin, and soft tissue, bones and joints, and blood.

Written By Dr. Mayank, Pharm.D,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 Sep 2025 | 12:11 AM (IST)

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General Information

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The content is shown in English

Product introduction

Staphonex 500mg Injection is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional.

This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine.

Allergic reactions, injection site reactions like pain, swelling or redness, vomiting, nausea, and diarrhea may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

Uses of Staphonex Injection

Bacterial infections

Benefits of Staphonex Injection

Bacterial infections
Staphonex 500mg Injection is an antibiotic medicine that works by killing the infection-causing bacteria in your body. It is effective for bacterial infections of the throat, ears, urinary tract, skin, and soft tissues. Staphonex 500mg Injection is given by a doctor or a nurse and should not be self-administered. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.

Side effects of Staphonex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Staphonex

Gastrointestinal disturbance

How to use Staphonex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Staphonex Injection works

Staphonex 500mg Injection is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive. This treats your infection.

Quick tips

You have been prescribed Staphonex 500mg Injection for the treatment of bacterial infections.
It is given by an injection into a vein or muscle, or via a drip into a vein.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
You have been prescribed Staphonex 500mg Injection for the treatment of bacterial infections.
It is given by an injection into a vein or muscle, or via a drip into a vein.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Staphonex 500mg Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Staphonex 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

Staphonex 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

SAFE

Staphonex 500mg Injection does not usually affect your ability to drive.

Kidney

CAUTION

Staphonex 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Staphonex 500mg Injection may be needed. Please consult your doctor.

Liver

CAUTION

Staphonex 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Staphonex 500mg Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Staphonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Flucloxacillin Sodium. Please consult your doctor. Flucloxacillin Sodium may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Flucloxacillin Sodium may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Flucloxacillin Sodium may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Amikacin (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Pemetrexed (Injection Route)

Your doctor may monitor your creatinine clearance along with your overall treatment and adjust the doses as per the observations. Flucloxacillin Sodium may slow down the removal of Pemetrexed from the body.

Moderate

Kanamycin (Injection Route)

Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.

Frequently asked questions

Can Staphonex 500mg Injection cause allergic reaction?

Although it is rare but yes, Staphonex 500mg Injection can cause allergic reaction and is harmful in patients with known allergy to penicillins. Get emergency medical help if you have any of the signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Fact Box

Chemical Class

Penicillins {Antibiotic analog of cloxacillin}

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Penicillinase-Resistant Penicillins

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

What are you using Staphonex Injection for?

Bacterial infections

100%

How much was the improvement?

Poor

83%

Average

17%

What were the side-effects while using Staphonex 500mg Injection?

No Side Effect

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fusion Healthcare Pvt Ltd
Address: Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Staphonex 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Staphonex 500mg Injection

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Expiry after

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Staphonex Injection

Benefits of Staphonex Injection

Side effects of Staphonex Injection

How to use Staphonex Injection

How Staphonex Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Amikacin (Injection Route)

Pemetrexed (Injection Route)

Kanamycin (Injection Route)

Frequently asked questions

Can Staphonex 500mg Injection cause allergic reaction?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

What are you using Staphonex Injection for?

How much was the improvement?

What were the side-effects while using Staphonex 500mg Injection?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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