1mg, best e pharmacy in India




Pemetrexed is used in the treatment of a type of lung cancer called non-squamous non-small cell lung cancer and in the treatment of another cancer called malignant pleural mesothelioma (a type of cancer that originates from the lining of the various organs of the body).

How it works

Pemetrexed belong to class of chemotherapy drugs called folate antimetabolites. It disrupts certain metabolic processes essential for cancer cell replication and multiplication.

Common side effects

Nausea, Muscle pain, Joint pain, Shortness of breath, Chest pain, Constipation, Depression, Fatigue, Dizziness, Headache, Insomnia, Decreased white blood cell count, Loss of appetite, Mood changes, Vomiting, Weight loss


Showing 10 of 18

Expert advice

  • You should always take vitamin B12, folic acid, and corticosteroids along with pemetrexed.
  • Tell your doctor, if you have been recently vaccinated. 
  • Tell your doctor if you have heart disease or history of heart disease, kidney or liver disorder.
  • Your blood samples will be evaluated to check kidney and liver function and blood cell count before each pemetrexed infusion.
  • If you have had or are going to have radiation therapy, tell your doctor, as there may be an early or late radiation reaction with pemetrexed. 
  • Consult your doctor regarding contraception and ensure to use contraception when on treatment with Pemetrexed and up to 6 months thereafter.
  • Tell your doctor if you are pregnant or think you may become pregnant or breast-feeding.

Frequently asked questions


Q. Is pemetrexed a vesicant?
No. Pemetrexed is not a vesicant.
Q. Is pemetrexed a chemotherapy/ cytotoxic?
Yes. Pemetrexed is chemotherapy and a cytotoxic drug.
Q. Is pemetrexed safe?
Pemetrexed is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Does pemetrexed cause hair loss?
Yes. Pemetrexed is a prescription chemotherapy medication and hair loss is one of the possible side effects.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)