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MMST, MBBS
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MD Pharmacology, MBBS
Last updated
23 Jan 2026 | 10:15 AM (IST)

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Sompraz 20 Tablet

rx_imgPrescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Sompraz 20 Tablet is used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. It reduces the amount of acid produced in the stomach and provides relief from symptoms and promotes healing.

Sompraz 20 Tablet can also be used to prevent stomach ulcers caused by certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Take it in the exact dose and duration prescribed by your doctor. It is usually taken on an empty stomach, preferably in the morning or at least 1 hour before a meal. Continue taking the medicine even if your symptoms disappear until the doctor says it is okay to stop. If you are taking this medicine for a long time, your doctor may carry out regular tests to check your levels of magnesium, which can fall with this medicine.


Common side effects include headache, constipation or diarrhea, stomach pain, and nausea. These tend to be mild, but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. You may be more likely to have a broken bone if you take it for a long time. It is best to avoid foods that seem to make your symptoms worse, such as rich, spicy, and fatty foods. Cutting down on caffeinated drinks, such as tea, coffee, and cola, as well as alcohol, may also help.


Sompraz 20 Tablet may not be suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have had an allergic reaction to similar medicines in the past, or have osteoporosis. Alcohol does not interfere with the way Sompraz 20 Tablet works; however, drinking alcohol makes your stomach produce more acid than normal. This medicine can make you feel dizzy, sleepy, or affect your vision. If this happens, do not drive, cycle, or use machinery or tools until you feel better. This medicine is not usually recommended during pregnancy and breastfeeding.


Uses of Sompraz Tablet

Benefits of Sompraz Tablet

In Acidity

Sompraz 20 Tablet helps relieve the discomfort caused by excessive stomach acid, such as burning sensations, sour stomach, or acid regurgitation. By reducing acid production, it soothes the stomach lining and prevents irritation, providing fast and lasting relief. For individuals suffering from frequent acidity, Sompraz 20 Tablet improves their quality of life by enabling them to enjoy meals and daily activities without the discomfort and inconvenience of acid-related symptoms.

In Gastroesophageal reflux disease (Acid reflux)

Sompraz 20 Tablet helps manage GERD by reducing the flow of stomach acid into the esophagus, which causes the burning sensation of heartburn and other acid reflux symptoms. This helps alleviate discomfort, protects the esophagus from long-term damage, and minimizes complications like inflammation or narrowing of the esophagus.

In Peptic ulcer disease

In individuals with peptic ulcer disease, Sompraz 20 Tablet helps reduce stomach acid levels, which allows the ulcers to heal more effectively and prevents further damage to the stomach lining. It also helps reduce symptoms like pain, nausea, and indigestion. By promoting healing and preventing the recurrence of ulcers, Sompraz 20 Tablet improves patients’ comfort and restores normal digestion, improving their overall well-being.

In Treatment of Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production can cause severe symptoms like diarrhea, abdominal pain, and ulcers. Sompraz 20 Tablet reduces this overproduction of acid, helping to control symptoms and prevent complications like bleeding ulcers. By managing acid levels effectively, the medicine allows patients to lead a more comfortable and active life without being constantly disrupted by severe digestive symptoms.

Side effects of Sompraz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sompraz

  • Vomiting
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Headache
  • Fundic gland polyps

How to use Sompraz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sompraz 20 Tablet is to be taken on an empty stomach.

How Sompraz Tablet works

Sompraz 20 Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sompraz 20 Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Sompraz 20 Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Sompraz 20 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Sompraz 20 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Sompraz 20 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Sompraz 20 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

What if you forget to take Sompraz Tablet?

If you miss a dose of Sompraz 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Sompraz 20 Tablet
₹7.13/Tablet
NexPRO 20 Tablet
Torrent Pharmaceuticals Ltd
₹7.67/tablet
8% costlier
Esoz 20 Tablet
Integrace Pvt Ltd
₹8.33/tablet
17% costlier
NexPRO Fast 20 Tablet
Torrent Pharmaceuticals Ltd
₹11.8/tablet
65% costlier
₹6.51/tablet
9% cheaper
Esofine 20mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹5.67/tablet
20% cheaper

Quick tips

  • Sompraz 20 Tablet is best taken 1 hour before a meal, preferably in the morning.
  • Avoid drinking alcohol, smoking cigarettes, and excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, and caffeinated beverages like tea and coffee.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days, as you may be suffering from some other problem that needs attention.
  • Long-term use of Sompraz 20 Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Chemical Class
Sulfinylbenzimidazoles
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors

Interaction with drugs

Taking Sompraz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Do not consume Erlotinib with Esomeprazole. Esomeprazole may reduce blood levels of Erlotinib.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Patient concerns

My ige level is 1600 and i feel uncomfortable in cold weather and facing problem of acid reflux also.what treatment i should take
Dr. Sunil Sekhri
Diabetology
send scan copy of reports. Take Tab Sompraz 20 1 empty stomach x 5 days
Many a times I feel acid reflux in the evening. Need help with diet to avoid that
Dr. Sfurti Mann
Internal Medicine
Avoid oily spicy food , eat small frequent meals can take tab sompraz IT before breakfast.

User feedback


FAQs

What is the best time to take Sompraz 20 Tablet?

Usually, Sompraz 20 Tablet is taken once a day, first thing in the morning. If you take Sompraz 20 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.

Can I take antacids along with Sompraz 20 Tablet?

Yes, you can take antacids along with Sompraz 20 Tablet. Take it 2 hours before or after you take Sompraz 20 Tablet.

Can I take Sompraz 20 Tablet for a long term?

Sompraz 20 Tablet is usually prescribed for short-term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger-Ellison syndrome (ZES), Sompraz 20 Tablet may be prescribed for a long-term duration as well. Long-term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Sompraz 20 Tablet as advised by your doctor and under their supervision.

Can I stop taking Sompraz 20 Tablet if I feel better?

If you have been taking Sompraz 20 Tablet for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Sompraz 20 Tablet.

What are the long term side effects of Sompraz 20 Tablet?

If Sompraz 20 Tablet is used for more than 3 months, certain long-term side effects may be seen. The most important of these is low magnesium levels in your blood, which may make you feel tired, confused, dizzy, or shaky. You may also have muscle twitches or an irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections, and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally, you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas), or nerve problems such as numbness, tingling, and problem in walking.

Can I take alcohol with Sompraz 20 Tablet?

No, alcohol intake is not advised with Sompraz 20 Tablet. Alcohol itself does not affect the working of Sompraz 20 Tablet, but it can increase the acid production. This may further cause worsening of your symptoms.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Esomeprazole [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals; 2014. [Accessed 28 Mar. 2019] (online) Available from: External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: External Link
  3. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from: External Link
  4. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from: External Link
  5. Esomeprazole [Summary of Product Characteristics]. Waterford, Ireland: Haleon Ireland Dungarvan Limited; 2025.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205
Country of origin: India
Expires on or after: April, 2026

A licensed vendor partner from your nearest location will deliver Sompraz 20 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP115.31  7% OFF
107
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15.0 tablets in 1 strip
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