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Sirotem Injection

Prescription Required
Store below 30°C

Product introduction

Sirotem Injection is used as a chemotherapy agent for the treatment of kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells). It works by blocking abnormal proteins that causes the multiplication of cancer cells. This helps in slowing the growth of tumors.

Sirotem Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

Some common side effects of this medicine include rash, weakness, nausea, edema, loss of appetite, anemia, increased glucose level in the blood,  increased blood lipid level, and increased alkaline phosphatase level in blood. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, and swelling.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body.

Benefits of Sirotem Injection

In Treatment of Kidney cancer

Sirotem Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Treatment of Mantle-cell lymphoma

Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Sirotem Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Sirotem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sirotem

  • Rash
  • Weakness
  • Nausea
  • Edema (swelling)
  • Decreased white blood cell count
  • Increased glucose level in blood
  • Anemia (low number of red blood cells)
  • Loss of appetite
  • Increased blood lipid level
  • Increased alkaline phosphatase level in blood

How to use Sirotem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sirotem Injection works

Sirotem Injection is a kinase inhibitor. It shows its action by blocking the action of the abnormal protein that causes the multiplication of cancer cells. This may help slow the growth of tumors.

Safety advice

It is not known whether it is safe to consume alcohol with Sirotem Injection. Please consult your doctor.
Sirotem Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
Sirotem Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Sirotem Injection does not usually affect your ability to drive.
Sirotem Injection is safe to use in patients with kidney disease. No dose adjustment of Sirotem Injection is recommended.
Sirotem Injection should be used with caution in patients with liver disease. Dose adjustment of Sirotem Injection may be needed. Please consult your doctor.
Use of Sirotem Injection is not advised in some patients with moderate to severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Sirotem Injection
4% costlier
Torisel Kit
Pfizer Ltd
55% costlier

Quick tips

  • Sirotem Injection is given for the treatment of kidney cancer.
  • Sirotem Injection interferes with wound healing, so it is advisable to use with caution if you have any scheduled surgery.
  • Inform your doctor if you have diabetes as the use of Sirotem Injection might increase the level of blood sugar. Report excessive thirst or any increase in the volume or frequency of urination.
  • Report immediately for the occurrence of infections or any new or worsening abdominal pain or blood in their stools after using Sirotem Injection.
  • Your doctor will monitor your cholesterol level as Sirotem Injection might increase the level of serum triglycerides and cholesterol.
  • The use of live vaccines, and close contact with those who have received live vaccines, while on Sirotem Injection should be avoided.

Fact Box

Chemical Class
Macrolide Lactams
Habit Forming
Therapeutic Class
Action Class
Immunosuppressant- mTOR inhibitors

Patient concerns

Symptoms of lymphoma And blood cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms could be like fever, weight loss, anorexia, lymphadenopathy.
Can we take homeopathic and ayurveda medicines together to cure lymphoma hockings cancer
Dr. Manju Singh
No. You can one pathy as supportive treatment with allopathy treatment.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1743-45.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1325.
  3. Temsirolimus. Sandwich, Kent: Pfizer Limited; 2007 [revised Jan. 2019]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Temsirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc.; 2007 [revised Apr. 2007]. [Accessed 06 Apr. 2019] (online) Available from:External Link
  5. Temsirolimus. [Accessed 06 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Country of origin: India
Inclusive of all taxes
1 ml in 1 vial
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