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MD (Pharmacology), MBBS
Last updated:
16 Jan 2020 | 04:22 PM (IST)
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Sirotem Injection


Overview

Introduction

Sirotem Injection is used as a chemotherapy agent for the treatment of kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells).

Sirotem Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

The common side effects of this medicine are rash, weakness, nausea, edema (swelling), loss of appetite, etc. It may also cause an injection site reaction (redness, pain, and swelling). If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.).

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body.

Uses of Sirotem Injection

Side effects of Sirotem Injection

Common
  • Rash
  • Nausea
  • Bacterial infection
  • Breathlessness
  • Constipation
  • Cough
  • Decreased potassium level in blood
  • Decreased white blood cell count
  • Decreased white blood cell count (neutrophils)
  • Diarrhea
  • Fatigue
  • Headache
  • Increased glucose level in blood
  • Insomnia (difficulty in sleeping)
  • Low blood platelets
  • Stomatitis (Inflammation of the mouth)
  • Taste change
  • Viral infection
  • Vomiting

How to use Sirotem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sirotem Injection works

Sirotem Injection is a kinase inhibitor. It shows its action by blocking the action of the abnormal protein that causes the multiplication of cancer cells. This may help slow the growth of tumors.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sirotem Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sirotem Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Sirotem Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Sirotem Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Sirotem Injection is safe to use in patients with kidney disease. No dose adjustment of Sirotem Injection is recommended.
Liver
CAUTION
Sirotem Injection should be used with caution in patients with liver disease. Dose adjustment of Sirotem Injection may be needed. Please consult your doctor.
Use of Sirotem Injection is not advised in some patients with moderate to severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Sirotem Injection
₹48000.0/ml of Injection
₹50000/Injection
4% costlier
Torisel Kit
Pfizer Ltd
₹74300/ml of Injection
55% costlier

Quick Tips

  • Temsirolimus contains high levels of alcohol and should be taken with caution if you take alcohol in large quantities or if you have to drive or operate heavy machinery

Patient Concerns

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Metastatic kidney cancer stage 4
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Thanks for reaching out to meHe has progressive disease on sorafenib
Kidney cancer solution & medison stage detail not clear detail
Dr. Vijay Sharnangat
Medical Oncology and Hematology
I don't know why but I am not able to see your downloaded reports, so please type your reports by only conclusion.
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FAQs

Q. Is temsirolimus a chemotherapy agent?

Yes, temsirolimus is a chemotherapy agent and is used in the treatment of certain types of cancers like kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells

Q. Is temsirolimus cytotoxic, a kinase inhibitor?

Yes, temsirolimus is cytotoxic and kinase inhibitor

Q. Is temsirolimus a vesicant?

Temsirolimus is not a vesicant (irritant) drug

Q. What is temsirolimus used for?

Temsirolimus is used to treat advanced kidney cancer and previously treated mantle cell lymphoma (a type of lung cancer affecting lymph nodes)

Q. How does temsirolimus work?

Temsirolimus works by inhibiting a human protein chemical called mammalian target of rapamycin (mTOR) thereby blocking tumor or cancer growth.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1743-45.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1325.
  3. Temsirolimus. Sandwich, Kent: Pfizer Limited; 2007 [revised Jan. 2019]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Temsirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc.; 2007 [revised Apr. 2007]. [Accessed 06 Apr. 2019] (online) Available from:External Link
  5. Drugs.com. Temsirolimus. [Accessed 06 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
A licensed pharmacy from your nearest location will deliver Sirotem Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
MRP
48000
1 ml in 1 vial
Add To Cart
Online payment only
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