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Last updated:
31 Jul 2020 | 04:08 PM (IST)
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S-Amlosafe 5 Tablet

Prescription Required
SALT COMPOSITION
Salt Synonyms
Storage
Store at room temperature (10-30°C)
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Overview

Introduction

S-Amlosafe 5 Tablet is a medicine used to treat high blood pressure (hypertension) and to prevent angina (heart-related chest pain). It is a calcium channel blocker which helps to lower blood pressure and reduce the workload of the heart. This helps prevent heart attacks and strokes.

S-Amlosafe 5 Tablet may be prescribed alone or along with other medicines. The dose depends on what you are taking it for and the severity of your condition. You can take it at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

The most common side effects include fatigue, swelling in the feet or ankles, sleepiness, dizziness, flushing, and headache. Consult your doctor If any of these bother you, or get worse, or won't go away.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking – especially those used to treat high blood pressure or heart conditions. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Benefits of S-Amlosafe Tablet

In Hypertension (high blood pressure)

S-Amlosafe 5 Tablet is a calcium channel blocker. It works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. Take regularly, as prescribed for this medicine to be most effective, even if you feel better.

In Prevention of Angina (heart-related chest pain)

S-Amlosafe 5 Tablet belongs to a class of medicines known as a calcium channel blockers. It works by relaxing blood vessels so that blood can flow more easily around your body. This means that more oxygen gets to your heart and reduces the risk of getting chest pain (angina). This medicine should not be used to treat chest pain which is already happening. It is used to prevent or reduce the frequency of angina attacks. This medicine needs to be taken regularly as prescribed for it to work effectively. So, it is important to keep taking it even if you feel well and have no symptoms.

Side effects of S-Amlosafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of S-Amlosafe

  • Dizziness
  • Headache
  • Palpitations
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Fatigue

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Palpitations
    If this happens regularly after you take your medicine, try to take the medicine at a time when you can sit or lie down when the symptoms are worse. It may help to cut down on alcohol, smoking, caffeine and big meals as these might make the problem worse. If you are still having problems after a week, speak to your doctor as you may be offered a different type of medicine.
  • Coping with Flushing (sense of warmth in the face, ears, neck and trunk)
    Sip cold or iced drinks. Try cutting down on coffee, tea and alcohol. It might help to keep the room cool and use a fan. You could also spray cool water on your face. Wear layers of light clothing that you can easily take off if you overheat. Breathe deeply and try to relax. Have a lukewarm shower or bath instead of a hot one. Avoid smoking and cut down on alcohol. The flushing should go away after a few days. If it does not go away or causes problems, contact your doctor. There may be medicines that can help.
  • Coping with Fatigue
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.

How to use S-Amlosafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. S-Amlosafe 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How S-Amlosafe Tablet works

S-Amlosafe 5 Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with S-Amlosafe 5 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
S-Amlosafe 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
S-Amlosafe 5 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether S-Amlosafe 5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
S-Amlosafe 5 Tablet is safe to use in patients with kidney disease. No dose adjustment of S-Amlosafe 5 Tablet is recommended.
Liver
CAUTION
S-Amlosafe 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of S-Amlosafe 5 Tablet may be needed. Please consult your doctor.

What if you forget to take S-Amlosafe Tablet?

If you miss a dose of S-Amlosafe 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
S-Amlosafe 5 Tablet
₹4.6/Tablet
S-Amcard 5 Tablet
Systopic Laboratories Pvt Ltd
₹2.5/Tablet
save 46%
S-Amlong 5 Tablet
Micro Labs Ltd
₹8.9/Tablet
93% costlier
Eslo 5 Tablet
Zuventus Healthcare Ltd
₹9.46/Tablet
106% costlier
Asomex 5 Tablet
Emcure Pharmaceuticals Ltd
₹9.48/Tablet
106% costlier
Esam 5 Tablet
Torrent Pharmaceuticals Ltd
₹10.87/Tablet
136% costlier

Quick Tips

  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking S-Amlosafe 5 Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how S-Amlosafe 5 Tablet affects you. 
  • Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. 

Fact Box

Chemical Class
Dihydropyridinecarboxylic acids derivatives
Habit Forming
No

Interaction with Drugs

Taking S-Amlosafe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Samlodon, Amodep, Amleod
SERIOUS
Brand(s): Aprepit, Aprepep, Fos-Aprepitant
SERIOUS
Brand(s): Atazor, Atavir, Virataz
SERIOUS
Brand(s): Etovas
SERIOUS

Patient Concerns

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What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
Cardiology
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Heart pain blood pressure high blood sugar high
Dr. Saurabh Arora
Cardiology
Consult physician near u for proper examination and blood work up
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Do you have any questions related to S-Amlosafe 5 Tablet ?

User Feedback


FAQs

Q. How long does it take for S-Amlosafe to work?

S-Amlosafe starts working on the day it is taken. However, it may take weeks to see the full effect. You should continue taking the medicine even if you feel better or if you do not notice any considerable difference. Consult your doctor if you have any concerns or you feel worse after taking the medicine.

Q. Is S-Amlosafe bad for the kidneys?

No, there is no evidence that S-Amlosafe causes deterioration of kidney problems. S-Amlosafe can be used in normal doses in patients with kidney problems. In fact, its blood pressure-lowering effect helps to prevent injury to the kidneys due to hypertension.

Q. Should I take S-Amlosafe in the morning or at night?

S-Amlosafe can be taken anytime in the morning or evening, usually prescribed once daily. Take the medicine as advised by the doctor. It is advised to take it at the same time each day so that you remember to take it and consistent levels of medicine are maintained in the body.

Q. How long do I need to take S-Amlosafe?

You should keep on taking S-Amlosafe for as long as your doctor has recommended you to take it. You may need to take it lifelong. Do not stop taking it, even if you feel well or your blood pressure is well controlled. If you stop taking S-Amlosafe, your blood pressure may increase again and your condition may worsen.

Q. I have been told that I have to take S-Amlosafe for several years. Is it safe to take it for a long time?

S-Amlosafe is a blood pressure-lowering medicine. It does not cure hypertension but helps to keep the blood pressure under control for as long as you take. For this reason, blood pressure-lowering medicines may need to be taken for a long period of time or even life long. S-Amlosafe is safe and well tolerated by most people and does not have any lasting toxicity when taken for a long time. For best results, take it exactly as advised by the doctor. Do not stop taking this medicine without consulting your doctor first.

Q. I have developed swelling over my ankles after using S-Amlosafe. What should I do?

S-Amlosafe can cause ankle or foot swelling. Raise your legs while you are sitting down. Talk to your doctor if it does not go away.

Q. Do I need to change my diet while using S-Amlosafe?

Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking S-Amlosafe. Take a low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  2. Galappatthy P, Waniganayake YC, Sabeer MI, et al. Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: A randomized double blind controlled clinical trial. BMC Cardiovasc Disord. 2016;16:168. [Accessed 31 Jul. 2020]. (online) Available from:External Link
  3. Şen S, Demir M, Yiğit Z, et al. Efficacy and Safety of S-Amlodipine 2.5 and 5 mg/d in Hypertensive Patients Who Were Treatment-Naive or Previously Received Antihypertensive Monotherapy. J Cardiovasc Pharmacol Ther. 2018;23(4):318-328. [Accessed 31 Jul. 2020]. (online) Available from:External Link

Manufacturer/Marketer Address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
A licensed vendor partner from your nearest location will deliver S-Amlosafe 5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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