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Ketoprofen (30mg)
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Ruplast 30 Plaster is a pain-relieving medicine. It is used to treat conditions such as painful flare-ups of rheumatism, arthritis, strained muscles and tendons, and gout. It also used to treat other painful conditions of the bone or muscle and pain and inflammation following orthopedic surgery.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
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General Information
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Product introduction
Ruplast 30 Plaster should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do.
The common side effects of this medicine include vomiting, stomach pain, nausea, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
This medicine is generally considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders, or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine.
The common side effects of this medicine include vomiting, stomach pain, nausea, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
This medicine is generally considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders, or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine.
Uses of Ruplast Pouch
Benefits of Ruplast Pouch
Pain relief
Ruplast 30 Plaster is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by arthritis and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Ruplast 30 Plaster is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by arthritis and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Ruplast Pouch
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ruplast
- Vomiting
- Nausea
- Indigestion
- Stomach pain
How to use Ruplast Pouch
Take the medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Ruplast 30 Plaster should be taken with or after food.
How Ruplast Pouch works
Ruplast 30 Plaster is a non-steroidal anti-inflammatory drug (NSAIDs). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Quick tips
- You have been prescribed Ruplast 30 Plaster to relieve pain and inflammation.
- Take it with food or milk to prevent upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- Do not take indigestion remedies (antacids) within two hours of taking Ruplast 30 Plaster.
- Avoid consuming alcohol while taking Ruplast 30 Plaster as it can increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ruplast 30 Plaster. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Ruplast 30 Plaster during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
Ruplast 30 Plaster should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Ruplast 30 Plaster may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
You may feel sleepy, dizzy, faint, your eyesight may be affected or you may have a fit while taking Ruplast 30 Plaster and this may affect your ability to drive.
You may feel sleepy, dizzy, faint, your eyesight may be affected or you may have a fit while taking Ruplast 30 Plaster and this may affect your ability to drive.

Kidney
CAUTION
Ruplast 30 Plaster should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test is advised while you are taking this medicine. Use of Ruplast 30 Plaster is not recommended in patients with severe kidney disease.
Regular monitoring of kidney function test is advised while you are taking this medicine. Use of Ruplast 30 Plaster is not recommended in patients with severe kidney disease.

Liver
CAUTION
Ruplast 30 Plaster should be used with caution in patients with liver disease. Dose adjustment may be needed.
Interaction with drugs
Taking Ruplast with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Tacrolimus (Oral Route)
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Frequently asked questions
In a few cases, Ruplast 30 Plaster may cause an increase in blood pressure. Before taking Ruplast 30 Plaster, you should inform your doctor if you have high blood pressure. Also, inform your doctor about the medicines that you might be taking for it. Doctors prescribe this medicine to people with high blood pressure only if the benefits outweigh the risks. In fact, patients with uncontrolled blood pressure should be very careful and should regularly monitor their blood pressure while on Ruplast 30 Plaster.
Taking Ruplast 30 Plaster on an empty stomach may cause nausea, vomiting, upset stomach, burning sensation in food pipe, and stomach pain. Therefore, Ruplast 30 Plaster should be taken with a glass of water either with meals or just after meals. Your doctor may also recommend taking an antacid with Ruplast 30 Plaster to avoid stomach upset.
If you are taking high doses of Ruplast 30 Plaster or a long-term treatment or both, then you should restrict or avoid alcohol. The reason being, taking both of them together increases your chances of ulcers and bleeding. It may also result in holes in the stomach and intestine (gastrointestinal perforation). These are serious side effects of Ruplast 30 Plaster which may be life-threatening. Discuss with your doctor if you are not sure.
Avoid taking Ruplast 30 Plaster during pregnancy as it may put your pregnancy and your unborn baby at risk. There have been reports of miscarriage and defects in the heart of the baby. But, if it is necessary to take it, then your doctor may prescribe a low dose for the shortest duration. This is applicable for the first 6 months of pregnancy. Ruplast 30 Plaster should not be given during the last 3 months of pregnancy as it may cause various defects in the baby and may also prolong labor.
Yes, Ruplast 30 Plaster may cause sleepiness. It may also cause dizziness, visual disturbances, drowsiness, fits, and spinning sensation. Do not drive or operate heavy machinery if you experience these symptoms. Consult your doctor if you are not sure.
Take Ruplast 30 Plaster only as long as advised by your doctor. Do not take it for longer than the recommended period of time. Long-term treatment with Ruplast 30 Plaster and at high doses can cause an increased risk of heart attack, stroke, ulcers, bleeding, or holes in the stomach and intestine. These symptoms can occur at any time without warning.
Fact Box
Chemical Class
Benzophenones
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 627.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 759-60.
- Ketoprofen. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc; 2007. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Rusan Pharma Ltd
Address: 58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai – 400 067 (India).
Address: 58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai – 400 067 (India).
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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