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Ruplast 20 Plaster

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 14 Dec 2025 | 01:00 AM (IST)
Ruplast 20 Plaster is a pain-relieving medicine. It is used to treat pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation.
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General Information

The content is shown in English
Ruplast 20 Plaster image
Ruplast 20 Plaster image
Ruplast 20 Plaster image

Product introduction

Your doctor will explain how to use Ruplast 20 Plaster. Follow the instructions carefully to get the most benefit. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you to stop using it.

The most common side effect of this medicine is application site reactions such as redness and swelling. These are usually mild and resolve with time. If they do not go away or bother you, you should remove your patch and contact your doctor.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by some other medicines you are using. Let your doctor know all the other medicines you are taking or using to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Ruplast Transdermal Patch

Benefits of Ruplast Transdermal Patch

Pain relief
Ruplast 20 Plaster is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis. Use it as advised by the doctor to get the most benefit.

Side effects of Ruplast Transdermal Patch

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ruplast
  • Erythema (skin redness)
  • Inflammation

How to use Ruplast Transdermal Patch

Use this medicine in dose and duration as advised by your doctor. Check the label before use. Make sure the skin is clean and dry. Remove the protective liner of the patch. Do not touch the sticky side. With sticky side down, place the patch evenly onto the skin.

How Ruplast Transdermal Patch works

Ruplast 20 Plaster is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

Quick tips

  • Apply Ruplast 20 Plaster only on clean, dry, and non-irritated skin, preferably on your upper arm, chest, or back, where it will not rub off easily.
  • Do not apply heat (like a heating pad or hot water bottle) near the patch, as it can increase medicine absorption from Ruplast 20 Plaster and raise the risk of side effects.
  • Avoid direct sunlight on the Ruplast 20 Plaster area during use and for 2 weeks after removing it, since it can trigger serious skin reactions (photosensitivity).
  • Rotate application sites each time to avoid skin damage or irritation in the same spot.
  • If the Ruplast 20 Plaster loosens, press it back gently. Do not tape it or try to reapply a used patch, as this may affect medicine release.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Ruplast 20 Plaster during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Ruplast 20 Plaster during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Ruplast 20 Plaster in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Ruplast 20 Plaster in patients with liver disease.

Interaction with drugs

Taking Ruplast with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Ruplast 20 Plaster is a medication used to relieve pain and inflammation in muscles, joints, and soft tissues. It is commonly used for conditions like arthritis, sprains, strains, and back pain. It is applied as a patch to the skin that delivers the active substance.
You should wash and dry the affected area thoroughly. Apply the prescribed Ruplast 20 Plaster to the affected skin and gently press the patch firmly. Wash your hands after application, unless your hands are being treated. Also, avoid covering the area with tight bandages unless directed by your doctor.
The common side effects of Ruplast 20 Plaster may include skin irritation, redness, or itching at the application site, dryness or peeling of the skin, mild burning or stinging sensation, etc. If you experience severe side effects like rash, swelling, or difficulty breathing, stop using the medication and seek medical help immediately.
No, avoid applying Ruplast 20 Plaster to broken, infected, or irritated skin. This can increase the absorption of the medication and raise the risk of side effects.
You may start feeling pain relief within a few hours of application. However, it may take a few days of regular use to see the full benefits.
No, Ruplast 20 Plaster is only for external use on the skin. It is not effective for headaches or internal pain.

Fact Box

Chemical Class

Benzophenones

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 627.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 759-60.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Rusan Pharma Ltd
Address: 58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai – 400 067 (India).

Vendor Details

Country of origin: India
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