Role 0.25mg Tablet

Ropinirole (0.25mg)

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Role 0.25mg Tablet is used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2025 | 05:06 PM (IST)

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General Information

Contains

Ropinirole (0.25mg)

Marketer

D D Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Role 0.25mg Tablet is taken by mouth preferably before bedtime with food to avoid nausea. However, take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as may result in harmful effects.

Some common side effects of this medicine includes headache, hallucination and confusion. Initially this medicine may cause sudden drop in the blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

It is important to inform doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful.

Uses of Role Tablet

Benefits of Role Tablet

Parkinson's disease
Parkinson’s disease is a progressive neurological disorder that affects movement, often causing tremors, stiffness, and difficulty with balance and coordination. Role 0.25mg Tablet helps manage these motor symptoms by supporting the brain’s dopamine activity, which is typically reduced in Parkinson’s. This can improve movement control, reduce tremors, and enhance daily functioning.

Restless leg syndrome
Restless leg syndrome causes an uncontrollable urge to move the legs, especially at night, often disturbing sleep. Role 0.25mg Tablet helps reduce these uncomfortable sensations and the urge to move, allowing for better sleep quality and improved comfort during rest periods.

Side effects of Role Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Role

Sleepiness
Vomiting
Weakness
Nausea
Edema (swelling)
Abnormality of voluntary movements
Indigestion
Confusion
Viral infection
Headache
Dizziness
Fainting
Hallucination

How to use Role Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Role 0.25mg Tablet should be taken with or after food.

How Role Tablet works

Role 0.25mg Tablet works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

All substitutes for Role 0.25mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Role 0.25mg Tablet to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
It can be taken with or without food. Taking it with food may reduce nausea.
For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
When you first start taking Role 0.25mg Tablet, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
Talk to your doctor in case you develop hallucinations or other changes in your behavior.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Role 0.25mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Role 0.25mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Role 0.25mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Role 0.25mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Role 0.25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Role 0.25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Role with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Ziprasidone (Oral Route)

If concurrent use is essential, please consult your doctor, they may monitor your treatment and adjust the doses as per the observations. Ziprasidone may reduce efficacy of Ropinirole.

Moderate

Leflunomide (Oral Route)

Your doctor may monitor the effects of Leflunomide when taken concurrently with Ropinirole. Leflunomide may reduce blood levels of Ropinirole.

Moderate

Asenapine (Oral Route)

If concurrent use is essential, please consult your doctor, they may monitor your treatment and adjust the doses as per the observations. Asenapine may reduce efficacy of Ropinirole.

Moderate

Estriol (Vaginal Route)

Your doctor may adjust the dose of Ropinirole according to the initiation or discontinuation of hormone replacement therapy (HRT). Estriol may slow down the removal of Ropinirole from the body.

Moderate

Allylestrenol (Oral Route)

Your doctor may adjust the dose of Ropinirole according to the initiation or discontinuation of hormone replacement therapy (HRT). Allylestrenol may slow down the removal of Ropinirole from the body.

Frequently asked questions

What are the warning symptoms that should prompt me to discontinue therapy?

You may develop several warning symptoms that would suggest that the treatment needs to be discontinued. You may develop compulsive behavior such as gambling, increase in sex drive, compulsive shopping and eating. You may notice that your symptoms are getting worse (start earlier than usual or are more intense, affect other parts of the body, such as the arms, and symptoms return early in morning). If you notice these symptoms, consult your doctor immediately.

How long does Role 0.25mg Tablet take to work?

You may be able to see improvement within a week. However, it may take longer and differs from individual to individual.

Can I stop taking Role 0.25mg Tablet if I do not see any improvement in my symptoms?

No, you should not stop taking Role 0.25mg Tablet on your own as you may experience anxiety, depression, lack of interest, tiredness, sweating and severe pain in the leg. The dose should be reduced slowly. In some patients, it may take longer to see improvement but not beyond 12 weeks. Talk to your doctor if you want to stop it.

Can I take gabapentin and Role 0.25mg Tablet together?

Yes, you can take gabapentin and Role 0.25mg Tablet together. However, be careful as taking these two medicines together may cause excessive drowsiness, dizziness and decrease your mental alertness. So, you may have to avoid driving, operating machinery or working at heights while taking the two medicines together.

Is Role 0.25mg Tablet used for pain?

No, Role 0.25mg Tablet is not used to relieve pain. It acts by increasing the levels of a chemical messenger (dopamine) in the brain, which is deficient in case of restless leg syndrome. This, in turn, relieves the discomfort and reduces the involuntary limb movements that disrupt night-time sleep.

How often can I take Role 0.25mg Tablet?

For restless leg syndrome, take Role 0.25mg Tablet once a day. It is usually taken just before bedtime, but you can take it up to 3 hours before going to bed. For Parkinson’s disease, it is usually taken three times a day.

Is Role 0.25mg Tablet safe?

Yes, Role 0.25mg Tablet is safe if taken in the dose and duration advised by your doctor. It is a well-tolerated medicine. The common side effects of Role 0.25mg Tablet are nausea, dizziness, headache, and sleepiness which are typically worse during the first two weeks of treatment and may require dose reduction but rarely discontinuation of drug.

Fact Box

Chemical Class

Indolines Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Dopamine Agonists

References

Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 475.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1234-35.
Ropinirole. Research Triangle Park, North Carolina: GlaxoSmithKline; 1997 [revised Aug. 2014]. [Accessed 23 Jan. 2019] (online) Available from:
Ropinirole. Burgos, Spain: Glaxo Wellcome S.A; 2017. [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ropinirole. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Ropinirole [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2014. [Accessed 20 Feb. 2024] (online) Available from:
Ropinirole. Bidminter, NJ: Alembic Pharmaceuticals Ltd.; 2025. [Accessed 08 Nov. 2025] (online). Available from:

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Restless leg syndrome

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: D D Pharmaceuticals
Address: G-1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur (Rajasthan)-302022

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Role 0.25mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Role Tablet

Benefits of Role Tablet

Side effects of Role Tablet

How to use Role Tablet

How Role Tablet works

All substitutes for Role 0.25mg Tablet

Ropark 0.25 Tablet

Adrole 0.25mg Tablet

Ropzee 0.25 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ziprasidone (Oral Route)

Leflunomide (Oral Route)

Asenapine (Oral Route)

Estriol (Vaginal Route)

Allylestrenol (Oral Route)

Frequently asked questions

What are the warning symptoms that should prompt me to discontinue therapy?

How long does Role 0.25mg Tablet take to work?

Can I stop taking Role 0.25mg Tablet if I do not see any improvement in my symptoms?

Can I take gabapentin and Role 0.25mg Tablet together?

Is Role 0.25mg Tablet used for pain?

How often can I take Role 0.25mg Tablet?

Is Role 0.25mg Tablet safe?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Role Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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