Riopah 0.5mg Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It helps to improve your exercising ability and will prevent the disease from getting worse.

Riopah 0.5mg Tablet can be taken with or without food. Take it regularly and take it at the same time each day to help you remember. Do not skip any doses and finish the full course of treatment even if you feel better. Do not stop taking the medicine suddenly without talking to your doctor.

Common side effects of this medicine include headache, indigestion, dizziness, nausea, diarrhea, hypotension, vomiting, anemia, gastroesophageal reflux, and constipation. Avoid driving or doing anything that requires mental focus until you know how this medicine affects you. Generally, most of its side effects usually resolve on their own and do not need any medical attention. However, you should consult with the doctor if you are bothered by any of the side effects.

Before using this medicine, let your doctor know if you have any preexisting medical conditions. Let your doctor also know about all the other medicines you are taking. Additionally, if you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. As it may cause harmful effects to the developing baby.

Uses of Riopah Tablet

Treatment of Pulmonary arterial hypertension (PAH)

Benefits of Riopah Tablet

In Treatment of Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Riopah 0.5mg Tablet relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.

Side effects of Riopah Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Riopah

Headache
Vomiting
Nausea
Constipation
Hypotension (low blood pressure)
Diarrhea
Dizziness

How to use Riopah Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Riopah 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Riopah Tablet works

Riopah 0.5mg Tablet is a vasodilator. It works by widening the blood vessels that connect the heart to the lungs. This increases the blood supply to the lungs, which reduces the workload of the heart.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Riopah 0.5mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Riopah 0.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Riopah 0.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Riopah 0.5mg Tablet may cause side effects which could affect your ability to drive.
It may cause dizziness in some people. If this happens you should not drive or use machines.

Kidney

CAUTION

Riopah 0.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Riopah 0.5mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Riopah 0.5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Riopah 0.5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Riopah Tablet?

If you miss a dose of Riopah 0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Riopah 0.5mg Tablet

₹17.5/Tablet

Rioci 0.5mg Tablet

MSN Laboratories

₹25.8/tablet

47% costlier

Rioteph 0.5mg Tablet

Cipla Ltd

₹21.8/tablet

25% costlier

Quick tips

Your doctor has prescribed Riopah 0.5mg Tablet to treat high pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs.
It can help improve your quality of life and exercise ability.
Monitor your blood pressure regularly to help your doctor decide the correct dose for you.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Don't drive or do anything requiring concentration until you know how Riopah 0.5mg Tablet affects you.
Do not take Riopah 0.5mg Tablet if you are pregnant as it can cause serious birth defects.
Do not take Riopah 0.5mg Tablet if you are also taking a nitrate medicine such as nitroglycerin to treat high blood pressure or heart disease.

Fact Box

Chemical Class

Pyrazolopyridine Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Soluble guanylate cyclase (sGC) stimulator

Interaction with drugs

Taking Riopah with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Dipyridamole (Oral Route) Severe

Concurrent use may cause low blood pressure. Do not consume Riociguat with Dipyridamole.

Aminophylline (Oral Route) Severe

Concurrent use may cause low blood pressure. Do not consume Riociguat with Aminophylline.

Aminophylline (Injection Route) Severe

Concurrent use may cause low blood pressure. Do not consume Riociguat with Aminophylline.

Avanafil (Oral Route) Severe

Concurrent use may cause low blood pressure. Do not consume Riociguat with Avanafil.

Sildenafil (Oral Route) Severe

Concurrent use may cause low blood pressure. Do not consume Riociguat with Sildenafil.

View all drug interactions

Patient concerns

Having high Pulmonary Atrial Hypertension

Dr. Nabajit Talukdar

Cardiology

What medicines r u on

Hiii my wife having hurt patient ( pulmonary hypertension ) she's taking pulmonext 5mg tablet but this tablet is very costly for me of Rs. 1450/- 10tab. I want to know any another tablet available in same drugs with low price

Dr. Sfurti Mann

Internal Medicine

This can't be decided online Your doctor is the best judge about your patients pulmonary hypertension

Hello Dr. My Dad is facing High Pulmonary Hypertension of 63 and average is 32. He has liver cirrhosis as well, he is advised for liver transplant. As the PAH is high cannot proceed with the surgery. Can you please advise if there is any way out. Age : 49yrs. Medicines for heart taken at present is : Ambrisentan 5mg Assurance 20mg Trimium Inhaler.

Dr. Nabajit Talukdar

Cardiology

Currently no other treatment apart from ambrisantan n assurance will have to wait n see response to medicines if pulmonary pressure comes down only then surgery possible

User feedback

Patients taking Riopah 0.5mg Tablet

Thrice A Day

62%

Twice A Day

38%

How much was the improvement?

Average

100%

What were the side-effects while using Riopah 0.5mg Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Riopah Tablet?

With food

100%

Please rate Riopah 0.5mg Tablet on price

Expensive

67%

Average

33%

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Riociguat [FDA Label]. 2018 [Accessed 03 Dec. 2020]. (online) Available from:
Riociguat [EMC SmPC]. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2019 [Accessed 03 Dec. 2020]. (online) Available from:
Riociguat [Prescribing Information]. Whippany, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2017. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Lupin Ltd

Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.