Renolzin 500 SR Tablet
Prescription Required
Product introduction
Renolzin 500 SR Tablet is used for the management of angina (heart-related chest pain). It helps prevent new attacks of angina but does not stop an acute attack once started. It relieves chest pain by making the heart work more efficiently.
Renolzin 500 SR Tablet should be taken in the dose as advised by your doctor, at the same time each day. It can be taken with or without food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It prevents future harm. If you stop taking it, your chest pain may come back.
You can improve the health of your heart by making some lifestyle changes, such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, headache, dizziness, and constipation. Talk to your doctor if these bother you or do not go away.
Renolzin 500 SR Tablet may not be suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also, let your doctor know all other medications you are using, as some may affect or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.
Uses of Renolzin Tablet SR
Benefits of Renolzin Tablet SR
In Treatment of Angina (heart-related chest pain)
Renolzin 500 SR Tablet reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions with the amount of oxygen supply available without causing stress on the heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.
Side effects of Renolzin Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Renolzin
- Nausea
- Headache
- Dizziness
- Constipation
How to use Renolzin Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Renolzin 500 SR Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Renolzin Tablet SR works
Renolzin 500 SR Tablet is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing the heart muscle.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Renolzin 500 SR Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Renolzin 500 SR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Renolzin 500 SR Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Renolzin 500 SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Renolzin 500 SR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Renolzin 500 SR Tablet may be needed. Please consult your doctor.
Use of Renolzin 500 SR Tablet is not recommended in patients with severe kidney disease.
Use of Renolzin 500 SR Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Renolzin 500 SR Tablet should be used with caution in patients with liver disease. Dose adjustment of Renolzin 500 SR Tablet may be needed. Please consult your doctor.
Use of Renolzin 500 SR Tablet is not recommended in patients with moderate to severe liver disease.
Use of Renolzin 500 SR Tablet is not recommended in patients with moderate to severe liver disease.
What if you forget to take Renolzin Tablet SR?
If you miss a dose of Renolzin 500 SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Renolzin 500 SR Tablet improves HbA1c and blood sugar levels in diabetes patients.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Notify your doctor if you are taking any other medications along with Renolzin 500 SR Tablet.
- It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.
Fact Box
Chemical Class
Acetanilide & piperazine derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Late Sodium channel blocker- angina
Interaction with drugs
Taking Renolzin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Ranolazine with Aripiprazole.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ranolazine with Atazanavir.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ranolazine with Apomorphine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ranolazine with Apomorphine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ranolazine with Darunavir.
Concomitant use may affect heart rhythm and may be fatal.
Patient concerns
FAQs
What are the serious side effects of Renolzin 500 SR Tablet?
Renolzin 500 SR Tablet may cause changes in the electrical activity of the heart, which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint or lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Renolzin 500 SR Tablet may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.
I started taking Renolzin 500 SR Tablet about a week ago. Now I have noticed that my urine has become very dark, though I am taking plenty of fluids. Is there anything to worry about?
Dark urine while taking Renolzin 500 SR Tablet is not a common side effect, but it can sometimes happen. Monitor for other symptoms like yellowing of the skin/eyes (jaundice), severe fatigue, nausea, or unusual muscle pain. Consult your doctor as soon as possible to rule out any liver- or kidney-related issues. Check if you’re taking other medications that could cause urine discoloration, such as vitamins, antibiotics, or certain foods like beets.
In case I accidentally take an excess of Renolzin 500 SR Tablet, what will happen?
An excess of Renolzin 500 SR Tablet can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking, and you can even faint. If you have taken an excess of Renolzin 500 SR Tablet by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.
Is it safe to take Renolzin 500 SR Tablet if I am already taking metoprolol?
Yes, it is safe to take the Renolzin 500 SR Tablet and metoprolol together. Renolzin 500 SR Tablet has minimal effect on blood pressure in patients with angina.
I am a diabetic and am taking metformin. My doctor has prescribed Renolzin 500 SR Tablet, is it safe to take both together?
If you are taking metformin along with Renolzin 500 SR Tablet, you have to be careful since Renolzin 500 SR Tablet may increase the levels of metformin in the body, which can lead to metformin toxicity. Talk to your doctor, who will modify the dose of metformin.
I have been taking simvastatin to keep my cholesterol levels in check. Can I take Renolzin 500 SR Tablet with it?
It is recommended not to take simvastatin and Renolzin 500 SR Tablet together because it may cause simvastatin toxicity, which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take it, then take it exactly as advised by the doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
- Ranolazine [Prescribing Information]. Mahwah, NJ: Lifestar Pharma LLC; 2025. [Accessed 09 Apr. 2025] (online) Available from:
Marketer details
Name: Knoll Pharmaceuticals Ltd
Address: M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042
Country of origin: India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Renolzin 500 SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Renolzin 500 SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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