Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Reben 20 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Reben Tablet works

Reben 20 mg Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

In Depth Information on Reben Tablet

Expert advice for Reben Tablet

Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Reben 20 mg Tablet can decrease magnesium levels in blood. Get your magnesium levels checked regularly. You may need a magnesium supplement or need to discontinue your medicine.
Inform your doctor if you are suffering from osteoporosis as Reben 20 mg Tablet can weaken your bones by decreasing calcium levels in blood. You may need a calcium supplement, preferably calcium citrate.
Reben 20 mg Tablet is a well-tolerated medicine and provides relief for a long time.
It may take a few days to show its effect. You can take an antacid for a quick relief during this time unless your doctor has asked you not to use them.
Once you start feeling better, do not stop taking your medicine. Take it for the duration as advised by your doctor

Reben Tablet related warnings

Special precautions for Reben Tablet

Alcohol

CAUTION

Pregnancy

WEIGH RISKS VS BENEFITS

Reben 20 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation

CAUTION

Reben 20 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.

Driving

Reben 20 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Kidney

SAFE

Reben 20 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Reben 20 mg Tablet is recommended.

Liver

Reben 20 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Reben 20 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Reben Tablet?

If you miss a dose of Reben 20 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Reben Tablet

Frequently asked questions about Rabeprazole

Q. Is Reben an over the counter product?

No, Reben is not an over the counter product, it is available when prescribed by a doctor.

Q. Is Reben an antacid?

Reben is not an antacid. It belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach while antacids only neutralize the stomach acid by coating the stomach.

Q. Does Reben cause osteoporosis (thinning of bones)?

Yes, long term use of Reben can cause osteoporosis (thinning of bones). It decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of hip, wrist or spine. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.

Q. Can I take aluminum hydroxide and magnesium carbonate or other antacids with Reben?

Reben can be taken with antacids like aluminum hydroxide, magnesium carbonate or sodium bicarbonate. Reben takes a few days to show its effect, so antacids can be taken during that time for relief of acidity and heartburn. However, antacids should be taken two hours before or one hour after taking Reben as antacids can increase the pH of the stomach and decrease the action of Reben which requires a lower pH for its action.

Q. Does Reben have addictive potential?

No, Reben has no addictive potential. It shows no withdrawal symptoms when you stop using this medicine.

Q. Is Reben safe?

Yes, Reben is safe if taken for prescribed duration in prescribed doses as advised by your doctor. However, there are some very common side effects that you can experience at effective doses like nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Reben cause hair loss?

No, hair loss has not been reported as a side effect of Reben. Talk to your doctor in case there is excessive hair fall as it could be due to some underlying problem that needs attention.

Q. Does Reben cause flatulence (gas or bloating)?

Flatulence (gas) has been reported as a common side effect of Reben. Although it would be mild to moderate in nature and transient.

Q. Does Reben cause tinnitus (ringing in the ears)?

Tinnitus (ringing sensation in the ears) has not been seen as a side effect with the use of Reben. Talk to your doctor in case you have this problem as it could be due to some underlying condition that needs attention.

Q. Does Reben cause weight gain?

Weight gain has been reported as a rare side effect of Reben. Weight gain can add to your problem of acidity and heartburn. So, you must try to do some exercise and make healthy changes in your diet to control your weight.

Q. Does Reben expire?

Yes, like any other medicine, Reben also expires. Always check the expiry date on the pack of the medicine before using it.

Q. Does Reben cause constipation?

Constipation is a common side effect seen in patients using Reben. Making healthy lifestyle changes like doing yoga, taking high fiber diet and plenty of fluids will prevent constipation.

Q. Does Reben cause high blood pressure?

Reben is not reported to cause high blood pressure. In case you experience high blood pressure, talk to your doctor as it may need attention. Common side effects seen with Reben includes nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Does Reben cause headache?

Headache is reported as one of the common side effects of Reben. Please consult your doctor in case you experience an intolerable headache for a prolonged duration while taking Reben.

Q. Can I take Reben with ranitidine?

Yes, Reben can be taken with ranitidine. As Reben show its effect after some days, Ranitidine can be taken for immediate relief. No drug-drug interactions or change in side effect profile has been reported when they are used together compared to either drug alone.

Q. Can I take Reben with ibuprofen?

Reben can be taken with ibuprofen. Reben is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. Can I take Reben with paracetamol?

Reben can be taken with paracetamol. Reben is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

Q. How is Reben metabolized?

Reben is metabolized in the liver mainly by microsomal CYP450 enzymes (CYP2C19 and CYP3A4). Patients with poor CYP2C19 enzymatic activity will have higher levels of Reben for a long time and a better suppression of stomach acid.

Q. Can Reben be used for the treatment of throat infection?

No, Reben is not meant for throat infections. However, it may be given along with antibiotics and other drugs to protect the stomach from excessive acid secretion.

Q. Why is Reben used with cinitapride for some conditions?

Cinitapride increases the movement of the gut and is useful in the treatment of conditions like heartburn, dyspepsia and is also useful in the treatment of reflux esophagitis. It has much better efficacy when it is used with Reben.

Q. Does Reben play any role in treating ulcerative colitis?

Reben does not have any role in the treatment of ulcerative colitis. However, it can be given if there is associated dyspepsia or increased stomach acid secretion. Talk to your doctor before taking any treatment for ulcerative colitis.

Q. Can Reben be used for reflux esophagitis?

Yes, Reben is effective in the treatment of reflux esophagitis. It is a disease in which stomach acid or bile irritates and inflames the lining of the food pipe. Reben decreases the production of acid in the stomach and can help in healing the inflamed and eroded esophagus.The efficacy is better when it is given in combination with a prokinetic agent like domperidone.

Q. Is Reben being used for treating weight loss?

No, Reben is not used for the treatment of weight loss. It is a proton pump inhibitor and is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

Q. Is there any role of Reben in treating hiatus hernia?

A hiatus hernia is the bulging of the stomach into the chest through an esophageal opening in the diaphragm which is larger than the normal size. A hiatus hernia is associated with acidity and heartburn. Reben does not play any role in treating hiatus hernia, however, it can help in relieving the symptoms of acidity, heartburn and acid reflux.

Q. Can I take Reben with vitamin D?

Yes, vitamin D can be taken with Reben. Vitamin D is generally advised to be taken as a supplement with Reben as its long-term use decreases the absorption of calcium and cause calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist and spine fractures.

Q. How is Reben useful in the treatment of H. pylori?

Reben is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in the symptomatic relief by decreasing associated acidity, reflux, and heartburn.

Q. Can I take Reben with domperidone?

Reben can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone increases gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Q. Can long term use of Reben cause magnesium deficiency?

Long-term use of Reben can lower magnesium levels in patients taking multiple daily doses for a year or longer (at least 3 months). Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures, dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches or spasm of the voice box.

Severely interacts with other drugs like

Taking Reben with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Reben with Ritonavir

LIFE-THREATENING

Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax

Reben with Cilostazol

LIFE-THREATENING

Medicines with composition Cilostazol: Pencil, Zilast, Stozic, Preclaud, Pletoz

Reben with Indinavir

LIFE-THREATENING

Medicines with composition Indinavir: Indivan

Reben with Nitrazepam

SERIOUS

Medicines with composition Nitrazepam: Konit, Zipam, Enzed, Nitrosh, Nap, Nitraz, Nzm, Sopor, N Tra, Hypnoril, Nitab, Hypnocent, Nite, Nitrosun

Reben with Alprazolam

SERIOUS

Medicines with composition Alprazolam: Eurolam, Alwel, Tenzo, Indolam, Alzopam, Tensfree, Ezoprax, Aryalam, Lamad, Nucalm, Altok, Sozox, Sedate, P Zolam, Silam, Alprawin, Alcicalm, Alzom, Sinozol, Alzot, Romipraz, Wycalm, Avizolem, Reclam, Zopain, Acalm, Alzorix, Aldip, Zola, Alprogard, Rozin, Alprasan, Alz, Triota, Suzilam, Altrex, Zorest, Pax, Zolark, Sleepex, Zoem, Endep, Actirax, Tenso-F, Balzam, Prazil, Alproz, Trika, Anxinil, Nulam, Lampoz, Meriproz, Alprasafe, Tranquil, Enzitan, Norex, Nat, P Calm, P Kalm, Zolent, Exal, Alam, Alpose, Zenax, Zolorel, Arkalam, Alprocam, Alzonex, Tryzo, Bliz, D.D.Lam, Manorest, Prosanti, Notence, Texidep, Zolam, Zolipax, Alora, Eldezolam, Becalm, Alzokam, Aleez, Alprazol, Alprater, Nindra, Endax, Pacyl, Kaprolam, Adzolam, Alarm, Trapose, Xycalm, Ancolam, Alzex, Alprazone, Procalm, Alltop, Alpviram, Joliday, Zolin

Reben with Midazolam

SERIOUS

Medicines with composition Midazolam: Medzol, Mezolam, Midfast, Fulsed, Midosed, Midzee, Benzosed

Reben with Clobazam

SERIOUS

Medicines with composition Clobazam: Risure, Boze, Clobazed, Solzam, Clozop, Sloba, Clobakon, Oresta, Adinep, Clobakem, Bazzy, Kivizam, Clobanil, Adobe, Lobachek, C Baz, Lobaz, Cloam, Epiba

Reben with Clonazepam

SERIOUS

Medicines with composition Clonazepam: Panik, Klojet, Sezolan, Calm, Brispam, Naze, Clono, Sonazep, Closis, Ubitpam, Clonarey, Benzopin, Clona, Clozorix, Clonetic, Zemed, Klopam, Clonark, Clonar, Lonator, Klowin, CNZ, Lonin, Biopam, Zepam, Klon, Clozepam, Halopam, Clonzy, Clone, Lonapam, Q Zepam, Sezopam, Xenotril SL, Zapiz, Melzap, Petril, Ona, Onapil, Clonogem, Catier, Clonotril, Ozepam, Clonam IR, Monazepam, Calmstay, Prozepton, Emcloz, Ecotril, Epitril, Czam, Clonaxyl, Clonopam, Clonapik, Restovis, Norep, Liberta, Clozy, Restovel, Clovas

Reben with Sodium Bicarbonate

SERIOUS

Medicines with composition Sodium Bicarbonate: Sodamax, Sobinix, Sobimed, Soda Bicarb Glycerin

Reben with Flurazepam

SERIOUS

Medicines with composition Flurazepam: Nindral

Reben with Lorazepam

SERIOUS

Medicines with composition Lorazepam: Psycopan, Loract, Urpam, Loram, Anxionil, Biokalm, Larosh, Loranxit, Larox, Agipam, Loripam, Lorapax, Loxum, Tanzepam, Almazine, L. Pam, Lorvan, Lorazine, Loren

Reben with Magnesium Hydroxide

SERIOUS

Medicines with composition Magnesium Hydroxide: Mgmax

Reben with Etizolam

SERIOUS

Medicines with composition Etizolam: Etizom, Etimax, Etezole, Etilax, Etirest, Etimark, Etizep, Etilaam, Solopose, Lam ET, Suprabenz, Sylkam, Etizoram, New Zomnia

Reben with Chlordiazepoxide

SERIOUS

Medicines with composition Chlordiazepoxide: Equblam, Zepox, Raipox, Equiliser, Anxibrium, Poxid, Peaceoxide, Anxon H, Equilibrium, Cloxide, Librel, Anxizide

Reben with Diazepam

SERIOUS

Medicines with composition Diazepam: Dizapam, Zeopse, Karpam, Osopose, Peptica, Placidox, Anxol, D P M, Juniz Rds

Reben with Dipyridamole

MODERATE

Medicines with composition Dipyridamole: Cardiwell, Thrombonil

Reben with Methotrexate

MODERATE

Medicines with composition Methotrexate: Methosis, Metrex, Rhutrex, Meditrex, Mext, Vibzi, Meth

Reben with Phenytoin

MODERATE

Medicines with composition Phenytoin: Stoin, Marantin, Notian, Phenytoin Sodium, Phenozed, Episol, Neptoin, C-Toin, Protoin, Pna, Seztin, Atoin, Phenos

Reben with Spiramycin

MINOR

Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox

Reben with Erythromycin

MINOR

Medicines with composition Erythromycin: Arthrox, Ciresto, Eromax, Eromycin, Avithrocin, Denthrocin, E Cin, T Mycin, Suzithrocin, Methro, Erypsin, Eryn, Enzycare, Erigyn, Osomycin, Althrocin, Acnetoin, Eryster, Eryspic, Elthrocin, Etomin, Erythrocin, Erypal, Erythrokem, Agrocin, Eltocin, Eryspans, Elucin, EB, Erycon, Q Mycin, Erythrotone, Erythrol, Citamycin, Eroate, Erythromark, Citamycin P, E Mycin, Erytho

Reben with Digoxin

MINOR

Medicines with composition Digoxin: Digon, Cardioxin

Reben with Clopidogrel

MINOR

Medicines with composition Clopidogrel: Clopinorm, Hanatrel, Clopido, Klopy, Flo, Clopizen, Clopilet, Clopifine, Clopace, MYO, Clotnil, Clopicure, Deplatt, Plavix, Plagerine, Klotfree, Cloflow, Cidogrel, Adgril, Clopact, Aclotil, Ceruvin, Delgrel, Antiban, Superclop, Clolyse, C Grel, Clop, Cloprez, Nugrel, Carpigrel, Torplatt, Clopicheck, Clobest, Clopijoy

Reben with Roxithromycin

MINOR

Medicines with composition Roxithromycin: Zuroxy, Roxilim, Rox Thro, Ani Rox, Enirox, Serox, Marox, Roxup, Roxiden, Adrox, P Rox, Roxro, Cidocin, Roxall, Roxipax, Throxid, Ruben, Alrox, Karoxy, Ethirox, RO, Grox, Tilide, Tikrox, Roxcol, Roximin, Roxyron, Roxin, Rxn, Uthrox, Roxicon, J Roxy, Roxiwin, Roxson, Roxipol, Roxymycin, Starox, Indarox, RXT, V Rox, Roxalgo, Roxina, Altrox, Roxirap, Viroxx, Lomin, Virrox, Turex, Roxt, Veerox, Roxiba, Entrox, Remycin, Santrox, Roxtri, Biolide, Vonmycin, Throxin, Roxica, Bythro, M Rox, Roxitin, Synrox, Roxid, Roxilac, Vilrox, Roxeptin, Roxyrol, Q Rox, Aurox, Roxygo, Romithrax, Raxitid, Roxy, Roxikem, Roxywin, Rekthro, Xthrocin, Roxibest, Roxychem, Bactimycin, Roxipil, Roxicate, Roxikind, Throx, Roxibid, Roxith, Roxitec, G Rox, Roxywok, Roxigull, Ecrobid, Rokim, Roxon, Roxivista, Rithro, Ziroxy, Roxicard, Eroxy, Roxem, Roxinga, Roxiron, RT Cure, D Throcine, Sirox, Roxetomin

Reben with Clarithromycin

MINOR

Medicines with composition Clarithromycin: Clarimac, CLR, Claripax, O Clar, Clarinic, C Cin, Klarim, Klarinton, Cloff, Clavid, Mythrocin, Frank, Clarsaf, Calrcin, Clarcin, Clarital, Truclar, Claricin, Bioclar, Claribid, Klarcid, Clarie, Clarigard, Macrobid

Check Reben Tablet Interactions with other drugs

Information last updated by Dr. Varun Gupta, MD Pharmacology on 6th Feb 2018.

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