Medicine Overview of Razine Tablet
Nausea, Vomiting, Headache, Dizziness, Constipation, Weakness.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Razine 500mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Taking it with food may lessen the chance the Razine 500mg Tablet will upset the stomach.
Razine 500mg Tablet is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.
In Depth Information on Razine Tablet
Razine prevents new attacks of angina but does not stop an acute attack.
- Does not affect heart rate, blood pressure at rest or during exercise.
Improves HbA1c and blood sugar levels in diabetes patients.
- Avoid driving or using machinery if you feel dizzy after taking Razine.
May produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done 1 to 2 weeks after starting Razine.
- Notify your doctor if you are taking any other medications along with Razine
Razine Tablet related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Razine 500mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Razine 500mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
It is not known whether Razine 500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Razine 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Razine 500mg Tablet may be needed. Please consult your doctor.
Use of Razine 500mg Tablet is not recommended in patients with severe kidney disease.
Razine 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Razine 500mg Tablet may be needed. Please consult your doctor.
Use of Razine 500mg Tablet is not recommended in patients with moderate to severe liver disease.
If you miss a dose of Razine 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Frequently asked questions about Razine Tablet
Razine extended release (ER) means the pill is formulated in such a manner that the drug is released slowly over time and blood levels of a drug are more consistent. This has the advantage of taking fewer pills and also with a lesser gastrointestinal side effect.
Q. Do Razine and trimetazidine act in the same way?
No. Both Razine and trimetazidine are used for the treatment of angina but they work by a different mechanism. Razine works by blocking late sodium current channel during ischemia and thereby lessens the intracellular sodium and calcium overload. This relaxes heart muscles and decreases the oxygen requirement. This helps to prevent angina. Trimetazidine works by improves glucose utilisation of heart cells through inhibition of fatty acid metabolism.
The researcher has studied Razine in patients with non-ST-elevation coronary artery disease. It did not reduce the risk of death or recurrent heart attacks in patients, but it improves angina symptoms. It is approved for use in angina.
Q. Can I use rivaroxaban with Razine?
Yes. Combining these medications can increase the blood levels of rivaroxaban and increase the risk of serious bleeding complications. You may need a dose adjustment. If you have kidney disease, you should inform your doctor before using rivaroxaban together with Razine.
No. Razine is not approved for treatment of type 2 diabetes. Study have demonstrated its ability to decrease HbA1c (glycosylated haemoglobin) in patients with or without diabetes. This property may be useful in the treatment of patients having diabetes mellitus and angina.
Q. Can I take Razine with quetiapine?
No. Using Quetiapine with Ranolazine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.
Razine is used in a disease of the heart known as angina. It has been shown to improve exercise-induced chest pain and severity of angina.
Yes, there are alternative to Razine e.g.Ivabradine, nicorandil and trimetazidine for effective control of anginal symptoms.
Q. Can I take Razine with atorvastatin?
Yes. Razine may significantly increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and the breakdown of skeletal muscle tissue. It can be used with atorvastatin but with dose limitation (atorvastatin) and appropriate clinical monitoring. In some cases, this can cause kidney damage and even death.
No. Razine is not approved for treatment of atrial fibrillation (AF). The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.
No, Razine is not a beta blocker. It is used in the treatment of angina.
Q. Can I take Razine with haloperidol?
No. Razine should not be used with haloperidol. It may increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.
No. Razine is not approved for use in any of arrhythmia. The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.
Razine is contraindicated in patients with liver damage (cirrhosis). It should not be given with medicine like ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, saquinavir, carbamazepine, phenobarbital, phenytoin, rifampin.
No. Razine is not used in the treatment of diastolic heart failure. It is used in the treatment of angina.
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