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Ranojar Tablet 1000mg

Ranolazine (1000mg)
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Ranojar Tablet 1000mg is used for the management of angina (heart-related chest pain). It helps prevent new attacks of angina but does not stop an acute attack once started. It relieves chest pain by making the heart work more efficiently.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 19 Dec 2025 | 12:55 PM (IST)
₹266 MRP ₹294.3810% off 
 
 
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General Information

The content is shown in English
Ranojar Tablet 1000mg image
Ranojar Tablet 1000mg image

Product introduction

Ranojar Tablet 1000mg should be taken in the dose as advised by your doctor, at the same time each day. It can be taken with or without food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It prevents future harm. If you stop taking it, your chest pain may come back.


You can improve the health of your heart by making some lifestyle changes, such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, headache, dizziness, and constipation. Talk to your doctor if these bother you or do not go away.


Ranojar Tablet 1000mg may not be suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also, let your doctor know all other medications you are using, as some may affect or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.

Benefits of Ranojar Tablet

Treatment of Angina (heart-related chest pain)
Ranojar Tablet 1000mg reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions in the amount of oxygen supply available without causing stress on heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Side effects of Ranojar Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ranojar
  • Nausea
  • Headache
  • Dizziness
  • Constipation

How to use Ranojar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ranojar Tablet 1000mg may be taken with or without food.

How Ranojar Tablet works

Ranojar Tablet 1000mg is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing the heart muscle.

All substitutes for Ranojar Tablet 1000mg

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Ranojar Tablet 1000mg improves HbA1c and blood sugar levels in diabetes patients.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Notify your doctor if you are taking any other medications along with Ranojar Tablet 1000mg.
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ranojar Tablet 1000mg. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ranojar Tablet 1000mg during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ranojar Tablet 1000mg may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Ranojar Tablet 1000mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Ranojar Tablet 1000mg should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Ranojar Tablet 1000mg is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Ranojar Tablet 1000mg should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Ranojar Tablet 1000mg is not recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Ranojar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Apomorphine (Injection Route)

Do not consume Ranolazine with Apomorphine.
Life-threatening

Apomorphine (Sublingual route)

Do not consume Ranolazine with Apomorphine.
Life-threatening

Aripiprazole (Oral Route)

Do not consume Ranolazine with Aripiprazole.
Life-threatening

Atazanavir (Oral Route)

Do not consume Ranolazine with Atazanavir.
Life-threatening

Darunavir (Oral Route)

Do not consume Ranolazine with Darunavir.

Frequently asked questions

Ranojar Tablet 1000mg may cause changes in the electrical activity of the heart, which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint or lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Ranojar Tablet 1000mg may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.
Dark urine while taking Ranojar Tablet 1000mg is not a common side effect, but it can sometimes happen. Monitor for other symptoms like yellowing of the skin/eyes (jaundice), severe fatigue, nausea, or unusual muscle pain. Consult your doctor as soon as possible to rule out any liver- or kidney-related issues. Check if you’re taking other medications that could cause urine discoloration, such as vitamins, antibiotics, or certain foods like beets.
An excess of Ranojar Tablet 1000mg can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking, and you can even faint. If you have taken an excess of Ranojar Tablet 1000mg by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.
Yes, it is safe to take the Ranojar Tablet 1000mg and metoprolol together. Ranojar Tablet 1000mg has minimal effect on blood pressure in patients with angina.
If you are taking metformin along with Ranojar Tablet 1000mg, you have to be careful since Ranojar Tablet 1000mg may increase the levels of metformin in the body, which can lead to metformin toxicity. Talk to your doctor, who will modify the dose of metformin.
It is recommended not to take simvastatin and Ranojar Tablet 1000mg together because it may cause simvastatin toxicity, which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take it, then take it exactly as advised by the doctor.

Fact Box

Chemical Class

Anisoles

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Late Sodium channel blocker- angina

References

  1. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
  3. Ranolazine [Prescribing Information]. Mahwah, NJ: Lifestar Pharma LLC; 2025. [Accessed 09 Apr. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Agrosaf Pharmaceuticals
Address: Raman Tower, 2ND FLOOR, Sanjay Place, Agra, Uttar Pradesh 282002

Vendor Details

Country of origin: India
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