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Ramiven 50mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Ramiven 50mg Tablet is an anti-cancer medicine used in the treatment of metastatic breast cancer. It helps slow down the growth of cancer cells and eventually kill them. This way it treats the symptoms of breast cancer, such as breast lumps, bloody discharge from nipples, or changes in the breast shape.
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General Information

Contains

Abemaciclib (50mg)

Marketer

Eli Lilly and Company India Pvt Ltd
The content is shown in English
Ramiven 50mg Tablet image
Ramiven 50mg Tablet image

Product introduction

Ramiven 50mg Tablet may be taken with or without food and usually taken in combination with another medicine. The duration of treatment varies on the basis of an individual's need and response to the treatment. Take it in the exact dose and duration prescribed by your doctor. You may be asked for regular blood tests while taking this medication.

Common side effects of this medicine include hair loss, headache, cough, joint pain, dizziness, fatigue, and diarhhea. Neutropenia is a well-recognized adverse effect in which the number of your white blood cells gets reduced and the immune system gets weakened. As a result, you may be at greater risk of getting an infection. However, this side effect disappears rapidly once you stop taking the medicine.

Before using this medicine, let your doctor know if you have any pre-existing medical conditions. Also inform them about all the medications you are taking. Additionally, inform them if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Ramiven Tablet

  • Metastatic breast cancer

Benefits of Ramiven Tablet

Metastatic breast cancer
Ramiven 50mg Tablet helps treat breast cancer and may be used alone or in combination with other medicines or treatment modalities, like chemotherapy. This medicine is used when other medicines have not shown significant improvement and the cancer has spread to other parts as well. It relieves the symptoms of breast cancer, such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. Ramiven 50mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of such cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Ramiven Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ramiven
  • Fatigue
  • Infection
  • Abnormal blood cell count
  • Increased creatinine level in blood
  • Gastrointestinal toxicity
  • Weight loss
  • Stomatitis (Inflammation of the mouth)
  • Headache
  • Cough
  • Joint pain
  • Hair loss
  • Dizziness
  • Decreased white blood cell count (neutrophils)
  • Increased liver enzymes

How to use Ramiven Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ramiven 50mg Tablet may be taken with or without food.

How Ramiven Tablet works

Ramiven 50mg Tablet works by blocking the action of an abnormal protein that triggers the multiplication of cancer cells. This helps slow or prevent the spread of cancer cells.

Quick tips

  • Take Ramiven 50mg Tablet at the same time every day with or without food, but stick to one routine to keep drug levels steady in your body.
  • If you vomit after taking the dose, do not take another one. You should just wait for the next scheduled dose, unless your doctor advises otherwise.
  • Drink plenty of fluids daily to help your body process the medicine and stay hydrated, especially if you have diarrhea.
  • Avoid grapefruit or grapefruit juice, as it can increase the risk of side effects by interfering with how the medicine is broken down.
  • Use effective birth control while taking Ramiven 50mg Tablet and for at least 3 weeks after the last dose, as it may harm an unborn baby.
  • Ramiven 50mg Tablet is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ramiven 50mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ramiven 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ramiven 50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Ramiven 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Ramiven 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CAUTION
Ramiven 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Ramiven with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Atazanavir (Oral Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may adjust the dose or recommend a substitute of either of these medicines. Atazanavir may raise blood levels of Abemaciclib.
Severe

Clarithromycin (Oral Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may adjust the dose or recommend a substitute of either of these medicines. Clarithromycin may raise blood levels of Abemaciclib.
Severe

Clarithromycin (Injection Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may adjust the dose or recommend a substitute of either of these medicines. Clarithromycin may raise blood levels of Abemaciclib.
Severe

Clarithromycin (Oral Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may adjust the dose or recommend a substitute of either of these medicines. Clarithromycin may raise blood levels of Abemaciclib.
Severe

Clarithromycin (Oral Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may adjust the dose or recommend a substitute of either of these medicines. Clarithromycin may raise blood levels of Abemaciclib.

Frequently asked questions

Ramiven 50mg Tablet is a targeted therapy medicine used to treat hormone receptor-positive (HR+), HER2-negative breast cancer that has spread to other parts of the body (metastatic). It is often used in combination with other medications like fulvestrant or aromatase inhibitors.
Ramiven 50mg Tablet works by blocking CDK4 and CDK6 enzymes, which are responsible for the growth of cancer cells. By slowing down cell division, it helps control tumor growth, delay cancer progression, and improve survival in patients with hormone receptor-positive breast cancer.
Yes, diarrhea is a very common side effect of Ramiven 50mg Tablet and usually occurs in the first week of treatment. Your doctor may advise you to start anti-diarrheal medicine at the first sign of loose stools and drink plenty of fluids. If diarrhea persists or becomes severe, consult your doctor immediately.
Yes, serious side effects of Ramiven 50mg Tablet include lung inflammation (ILD/pneumonitis), blood clots (VTE), severe liver enzyme increase, and severe neutropenia (low white blood cell count). Symptoms like shortness of breath, chest pain, high fever, or yellowing of the eyes require urgent medical attention.
People who are allergic to Ramiven 50mg Tablet or any of its ingredients should not take Ramiven 50mg Tablet. Also, those with severe liver disease, a history of blood clots, or lung conditions should use it cautiously under a doctor’s supervision.
Yes, Ramiven 50mg Tablet can lower white blood cells (leading to a higher risk of infections) and increase liver enzymes (ALT/AST). Your doctor will monitor your blood tests regularly during treatment to ensure your safety.
The time Ramiven 50mg Tablet takes to show results varies from person to person. Your doctor will monitor your progress through regular check-ups, blood tests, and scans.
No, do not stop taking Ramiven 50mg Tablet without consulting your doctor. Stopping the medication abruptly can cause the cancer to grow or spread. Always follow your doctor’s instructions.
Avoid grapefruit or grapefruit juice, as it can increase the level of Ramiven 50mg Tablet in your body and raise the risk of side effects. Avoid activities that require alertness until you know how Ramiven 50mg Tablet affects you. Limit exposure to sunlight, as Ramiven 50mg Tablet may make your skin more sensitive to UV rays.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

  1. Abemaciclib [Prescribing Information]. Indianapolis, IN: Lilly USA, LLC; 2021. [Accessed 20 Feb. 2024] (online) Available from:
  2. Abemaciclib [Prescribing Information]. Madrid, Spain: Eli Lilly and Company (Ireland) Ltd.; [Accessed 14 Oct. 2025] (online)
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eli Lilly and Company India Pvt Ltd
Address: Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA

Vendor Details

Country of origin: India

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