


Protobid Plus Tablet
Methylpolysiloxane (50mg)+ Dicyclomine (6mg)+ Diloxanide (250mg)+ Tinidazole (300mg)
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Protobid Plus Tablet is used to treat diarrhea and abdominal pain. It works effectively to reduce abdominal pain, bloating, and cramps by relaxing the muscles of the stomach and gut. It neutralizes excessive acid in the stomach and helps in easy passage of gas. It also kills diarrhea-causing bacteria.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Sep 2025 | 03:31 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Sep 2025 | 03:31 PM (IST)
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General Information
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Product introduction
Protobid Plus Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, metallic taste, diarrhea, dryness in mouth, vomiting, stomach pain, flatulence, weakness, nervousness, headache, and blurred vision. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Immediately consult your doctor if you experience any allergic reactions such as skin rash, swelling, and itching.
The most common side effects are nausea, metallic taste, diarrhea, dryness in mouth, vomiting, stomach pain, flatulence, weakness, nervousness, headache, and blurred vision. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Immediately consult your doctor if you experience any allergic reactions such as skin rash, swelling, and itching.
Uses of Protobid Plus Tablet
Benefits of Protobid Plus Tablet
Abdominal pain
Protobid Plus Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation. This helps to treat abdominal pain (or stomach pain) as well as cramps, bloating and discomfort. Take Protobid Plus Tablet as prescribed to get maximum benefit. Eventually, it will help you to go about your daily activities more easily and have a more active and better quality of life.
Protobid Plus Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation. This helps to treat abdominal pain (or stomach pain) as well as cramps, bloating and discomfort. Take Protobid Plus Tablet as prescribed to get maximum benefit. Eventually, it will help you to go about your daily activities more easily and have a more active and better quality of life.
Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Protobid Plus Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Protobid Plus Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Side effects of Protobid Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Protobid Plus
- Nausea
- Dryness in mouth
- Metallic taste
- Vomiting
- Diarrhea
- Stomach pain
- Flatulence
- Sleepiness
- Weakness
- Nervousness
- Headache
- Dizziness
- Blurred vision
How to use Protobid Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Protobid Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Protobid Plus Tablet works
Protobid Plus Tablet is a combination of four medicines: methylpolysiloxane, dicyclomine, diloxanide and tinidazole.
Quick tips
- You have been prescribed Protobid Plus Tablet for the treatment of diarrhea and to get relief from abdominal pain.
- It is best to take it when the first sign of pain occurs.
- Diarrhea can cause water loss and electrolyte imbalance. Drink plenty of fluids especially ORS (oral rehydration solution) to help keep you hydrated.
- Consult your doctor if your diarrhea lasts for more than 48 hours even after taking Protobid Plus Tablet.
- Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Do not take any indigestion remedies (antacids) within two hours of taking this medicine.
Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Protobid Plus Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy
CONSULT YOUR DOCTOR
Protobid Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Protobid Plus Tablet during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Protobid Plus Tablet may cause side effects which could affect your ability to drive.
Protobid Plus Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.
Protobid Plus Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.

Kidney
CAUTION
Protobid Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Protobid Plus Tablet may be needed. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Protobid Plus Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Protobid Plus Tablet may not be needed in these patients. Please consult your doctor.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Related lab tests
References
- MedIndia. Methylpolysiloxane. [Accessed 24 Apr. 2019] (online) Available from:
- Dicyclomine. Birmingham, Alabama: Axcan Scandipharm Inc.; 2005. [Accessed 24 Apr. 2019] (online) Available from:
- Tinidazole. Atlanta, Georgia: Mikart Inc; 2004 [revised May 2007]. [Accessed 24 Apr. 2019] (online) Available from:
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User feedback
Abdominal pain
43%
Others
29%
Diarrhea
14%
Worm infections
14%
Poor
67%
Average
33%
Abdominal pain
100%
With food
100%
Average
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Iatros Pharmaceuticals Pvt Ltd
Address: Iatros Pharmaceuticals, Sonigra Chambers, Gultekadi, Market Yard Road, PB No 1416, Pune - 411037 (Maharashtra) India
Address: Iatros Pharmaceuticals, Sonigra Chambers, Gultekadi, Market Yard Road, PB No 1416, Pune - 411037 (Maharashtra) India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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