Prothipin 50 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 22 Feb 2026 | 06:32 PM (IST)

Prothipin 50 Tablet is a medicine used to treat depression and anxiety. It helps improve mood, reduce feelings of sadness or worry, and restore interest in daily activities. It works by increasing the levels of certain natural chemicals in the brain, which help improve mood and relieve anxiety.

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General Information

Contains

Dothiepin (50mg)

Marketer

Eventus Biotech Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Prothipin 50 Tablet should be taken exactly as prescribed by your doctor. It may be taken with or without food. Take it regularly and take it at the same time every day. Do not stop taking the medicine suddenly without your doctor's advice, as this can cause withdrawal symptoms or worsen your condition. Along with taking the medicine, follow a healthy lifestyle, get enough sleep, and attend regular follow-up appointments.

Some common side effects of Prothipin 50 Tablet include dry mouth, drowsiness, dizziness, constipation, and weight gain. These usually get better as your body adjusts to the medicine. Drinking plenty of water, eating a high-fibre diet, and avoiding alcohol may help reduce these side effects. If you feel extremely sleepy or dizzy, avoid driving or operating machinery. If any side effects become bothersome or do not go away, let your doctor know.

Before taking Prothipin 50 Tablet, inform your doctor if you have any heart, liver, or kidney problems, or a history of seizures or glaucoma. This medicine may not be suitable for people with certain medical conditions. Avoid drinking alcohol while taking Prothipin 50 Tablet, as it can increase drowsiness and worsen side effects. Let your doctor know about all the medicines you are taking, as some medicines may interact with Prothipin 50 Tablet. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Prothipin Tablet

Benefits of Prothipin Tablet

Treatment of Anxiety
Anxiety is a condition where a person feels constant worry, nervousness, or fear that can interfere with daily activities. Prothipin 50 Tablet helps calm the mind, reduces excessive worry, and promotes a sense of relaxation. With continued use, it improves sleep, focus, and overall quality of life by reducing the emotional burden of anxiety.

Treatment of Depression
Depression is a mental health condition that causes persistent sadness, low energy, and loss of interest in daily activities. Prothipin 50 Tablet helps improve mood, boosts emotional well-being, and restores interest in daily life, making it easier to function and cope with everyday challenges. Over time, it brings a sense of stability and positivity to people living with depression.

Side effects of Prothipin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prothipin

Dryness in mouth
Constipation
Weight gain
Headache
Low sexual desire

How to use Prothipin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothipin 50 Tablet may be taken with or without food.

How Prothipin Tablet works

Prothipin 50 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Quick tips

Take Prothipin 50 Tablet at bedtime, as it may cause drowsiness and help improve sleep in people with depression or anxiety.
Avoid alcohol while on this medicine, as it can increase sedation and worsen side effects like dizziness or confusion.
Inform your doctor if you experience dry mouth, blurred vision, or constipation, as these are common side effects that are usually manageable but should be monitored.
Do not stop Prothipin 50 Tablet suddenly. Your doctor will guide a tailored dose reduction to prevent withdrawal symptoms.
Let your doctor know if you have a heart condition, as this medicine can affect heart rhythm, especially in higher doses.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Prothipin 50 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Prothipin 50 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Prothipin 50 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Prothipin 50 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Prothipin 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Prothipin 50 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is Prothipin 50 Tablet and why is it prescribed?

Prothipin 50 Tablet is a tricyclic antidepressant used to treat major depressive disorder and the anxiety that often comes with it. It works by balancing certain brain chemicals that affect mood. Additionally, it may be used to manage certain types of nerve pain.

Who should not take Prothipin 50 Tablet?

Individuals should not take Prothipin 50 Tablet if they have epilepsy, are recovering from a recent heart attack, or have severe liver problems. Use is also not recommended in those currently taking or who have recently (within the past 14 days) taken MAOI medications. Prothipin 50 Tablet should be avoided in individuals who are allergic to dothiepin or any of the ingredients present in the formulation.

Can I stop taking Prothipin 50 Tablet suddenly?

No, stopping Prothipin 50 Tablet abruptly may cause withdrawal symptoms like headache, nausea, insomnia, irritability, or even seizures. Your doctor will always taper the dose gradually based on how well you respond to the medicine.

What are the most serious side effects of Prothipin 50 Tablet?

Although rare but serious effects of Prothipin 50 Tablet include suicidal thoughts especially in young adults, heart arrhythmias, liver problems, seizures, psychosis or mania, etc. If you experience any of these serious side effects, reach out to your doctor at the earliest.

How long does it take for Prothipin 50 Tablet to work?

The exact time Prothipin 50 Tablet takes to work is not known. It may take 2 to 4 weeks to feel the full effect. However, early signs of improvement can occur within the first two weeks. Keep taking it even if you do not feel better right away.

Can Prothipin 50 Tablet cause suicidal thoughts?

Yes, Prothipin 50 Tablet may cause suicidal thoughts, particularly in young adults (18 to 24 years of age). Close monitoring is crucial during the first few weeks or after any dose changes. You should report mood changes, agitation, or suicidal thoughts immediately to your doctor or your care taker.

What should I do in case of Prothipin 50 Tablet overdose?

Prothipin 50 Tablet overdose can be life-threatening with symptoms like irregular heartbeat, seizures, or coma. You should reach out to your doctor immediately if overdose is suspected. Do note that even small overdoses can be fatal.

Fact Box

Chemical Class

Dibenzothiepins

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Tricyclic Antidepressants (TCAs)

References

Dothiepin [Product Information]. NSW, Australia: Viatris; 2022.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eventus Biotech Pvt Ltd
Address: Khasra No 40//22/1,20/147 Part Village Mohra Ambala Cantt 133004

Vendor Details

Country of origin: India

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Prothipin 50 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Prothipin Tablet

Benefits of Prothipin Tablet

Side effects of Prothipin Tablet

How to use Prothipin Tablet

How Prothipin Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Prothipin 50 Tablet and why is it prescribed?

Who should not take Prothipin 50 Tablet?

Can I stop taking Prothipin 50 Tablet suddenly?

What are the most serious side effects of Prothipin 50 Tablet?

How long does it take for Prothipin 50 Tablet to work?

Can Prothipin 50 Tablet cause suicidal thoughts?

What should I do in case of Prothipin 50 Tablet overdose?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

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Disclaimer

Marketer details

Vendor Details

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