Proflox 0.3% Drop

Pefloxacin (0.3%)

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Proflox 0.3% Drop is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues, and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 10 Aug 2026 | 10:53 AM (IST)

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General Information

Contains

Pefloxacin (0.3%)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Proflox 0.3% Drop should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

You may experience nausea, headache, and dizziness as side effects of this medicine. These are usually temporary and resolve on their own. Consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.

Uses of Proflox Drop

Treatment of Bacterial infections

Benefits of Proflox Drop

Treatment of Bacterial infections
Proflox 0.3% Drop is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs, urinary tract, skin, and soft tissues in adults and children. It works by killing and stopping the growth of the bacteria causing the infection.
This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Proflox Drop

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Proflox

Nausea
Diarrhea
Headache
Dizziness

How to use Proflox Drop

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Proflox 0.3% Drop should be taken with or after food.

How Proflox Drop works

Proflox 0.3% Drop is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

Quick tips

Your doctor has prescribed Proflox 0.3% Drop to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Proflox 0.3% Drop and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor has prescribed Proflox 0.3% Drop to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Proflox 0.3% Drop and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Proflox 0.3% Drop. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Proflox 0.3% Drop is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Proflox 0.3% Drop may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Proflox 0.3% Drop may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Proflox 0.3% Drop in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Proflox 0.3% Drop should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Proflox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Pefloxacin. Please consult your doctor. Pefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).

Moderate

Acenocoumarol (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.

Moderate

Aceclofenac (Oral Route)

Do not consume Pefloxacin with Aceclofenac. If concurrent use is essential, watch out for convulsions and seizures and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations.

Moderate

Aceclofenac (Injection Route)

Frequently asked questions

Can the use of Proflox 0.3% Drop cause diarrhea?

Yes, the use of Proflox 0.3% Drop can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Can the use of Proflox 0.3% Drop increase the risk of muscle damage?

Yes, use of Proflox 0.3% Drop is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Proflox 0.3% Drop. Inform your doctor if you feel any kind of muscle pain while using this medicine.

Fact Box

Chemical Class

Quinoline carboxylic acids

Habit Forming

Therapeutic Class

OPHTHAL OTOLOGICALS

Action Class

Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

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Proflox 0.3% Drop

Proflox 0.3% Drop

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Proflox Drop

Benefits of Proflox Drop

Side effects of Proflox Drop

How to use Proflox Drop

How Proflox Drop works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Acenocoumarol (Oral Route)

Aceclofenac (Oral Route)

Aceclofenac (Injection Route)

Frequently asked questions

Can the use of Proflox 0.3% Drop cause diarrhea?

Can the use of Proflox 0.3% Drop increase the risk of muscle damage?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests