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Predemed 125mg Injection

Methylprednisolone (125mg)
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Predemed 125mg Injection is a type of medicine called a steroid. It is used to treat different conditions including rheumatic disorder, asthma, severe allergic reactions and conditions that affect your eyes and skin.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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Predemed 125mg Injection image
Predemed 125mg Injection image

Product introduction

Predemed 125mg Injection is usually given as an injection by your doctor into a vein, joint, or muscle. The amount you are given will depend on what you are being treated for and how much you need to control your symptoms. If you are using this medication at home, learn exactly how to do it correctly from your doctor. You should always take the amount prescribed. Do not take a larger dose or use it more often. Taking a higher dose will not improve your condition faster, and your risk of side effects will increase. Keep taking it regularly even if you feel well. Do not suddenly stop this medication as your condition may become worse. It should always be stopped gradually.

The most common side effects of this medicine include nausea, headache, dizziness, sweating, and swelling in your hands or ankles (edema). If these side effects bother you or will not go away, your doctor may suggest ways of preventing or reducing them. Steroids may also lower your ability to fight infections so avoid being near people who might pass on infections such as measles, chickenpox, or flu. Do not receive a live vaccine while using this medicine. Steroids can affect growth in children.

Before using this medicine, you should tell your doctor if you have brittle bones (osteoporosis), mood disorders, high blood pressure, or liver disease. Also, tell your doctor if you have diabetes, this medicine may increase blood glucose levels which can worsen diabetes. Many other drugs may affect, or be affected by, this medicine so let your doctor know all other medicines you are using. This is done to make sure it is safe to use. You should also tell your doctor if you are pregnant, planning to become pregnant or breastfeeding. If this medicine is used for a long time you will be asked for regular monitoring of blood sugar, blood pressure, bone density as well as an eye examination.

Uses of Predemed Injection

Benefits of Predemed Injection

Treatment of Allergic conditions
Predemed 125mg Injection is used to treat different inflammatory and allergic conditions including arthritis, lupus, psoriasis, ulcerative colitis which affect the skin, blood, eyes, lungs, stomach, and nervous system. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching and other allergic-type reactions.
This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Treatment of Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Predemed 125mg Injection prevents the release of substances in the body that cause inflammation. It lowers your immune system’s response and reduces symptoms such as swelling, pain, itching and other allergic-type reactions.
Treatment of Skin disorders
Predemed 125mg Injection prevents the release of substances in the body that cause inflammation. It can be used to treat different inflammatory and allergic conditions of the skin such as eczema and psoriasis. It works by lowering your immune system’s response to these conditions thereby relieving symptoms such as swelling, pain, itching and other allergic-type reactions.
Treatment of Eye disorders
Predemed 125mg Injection helps relieve symptoms of eye infections such as redness, swelling, itching and watering of eyes. This medicine works by decreasing the production of certain chemicals that cause inflammation of the eyes. This will make it easier for you to go about your daily activities. Use it as prescribed to get the most benefit. If you see no improvement even after a week, talk to your doctor.
Treatment of Rheumatic disorder
Rheumatic disorder is an autoimmune condition where your body’s immune system (which usually fights bacteria and viruses) attacks your body’s own cells. Predemed 125mg Injection stops that from happening and can relieve the symptoms of this condition such as pain, swelling, and stiffness in your joints. It can also slow down joint damage, reduce disability, and enable you to be as active for as long as possible. It can take several weeks or months to notice the effect of the medicine. You should continue taking it until your doctor says it is okay to stop using the medicine.

Side effects of Predemed Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Predemed
  • Nausea
  • Behavioral changes
  • Sweating
  • Edema (swelling)
  • Mood changes
  • Upset stomach
  • Thinning of skin
  • Increased risk of infection
  • Reduction in bone density

How to use Predemed Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Predemed Injection works

Predemed 125mg Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

Quick tips

  • Predemed 125mg Injection helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Predemed 125mg Injection can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Do not stop taking Predemed 125mg Injection suddenly without talking to your doctor first as it may worsen your symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Predemed 125mg Injection
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Predemed 125mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Predemed 125mg Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Predemed 125mg Injection may cause side effects that could affect your ability to drive.
Undesirable effects, such as dizziness, vertigo, visual disturbances and fatigue are possible after treatment with Predemed 125mg Injection. This may affect your driving ability.
Kidney

Kidney

SAFE IF PRESCRIBED
Predemed 125mg Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Predemed 125mg Injection in patients with liver disease.

Interaction with drugs

Taking Predemed with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Methylprednisolone may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Methylprednisolone with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Methylprednisolone may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Methylprednisolone before taking Purified Vi Polysaccharide Typhoid Vaccine.
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Loperamide (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Predemed 125mg Injection works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. In addition to that, it stops the autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.
Yes, Predemed 125mg Injection is a steroid medicine also known as corticosteroids which occur naturally in the body. These corticosteroids help to maintain health and wellbeing. Predemed 125mg Injection increases the levels of corticosteroids in the body by treating various illnesses involving inflammation (redness, tenderness, heat and swelling).
Predemed 125mg Injection has anti-inflammatory and immunosuppressant properties. It is used to treat conditions like allergic conditions, anaphylaxis, asthma, rheumatoid arthritis and inflammatory skin diseases. It is also helpful in treating autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage) and certain eye disorders.
Predemed 125mg Injection should be administered by a doctor or under the supervision of a healthcare professional and should not be self-administered. Usually, it is given into a muscle (intramuscular), joint (intra-articular), directly into a vein (direct intravenous), infusion or into the area being treated (soft tissue infiltration). The doctor will decide the dose based on the condition you are being treated for and also your body weight. Follow your doctor’s instructions carefully to get maximum benefit from Predemed 125mg Injection.
Clinical studies have shown that Predemed 125mg Injection is more strong and efficient than Prednisone. It stays in our body for a longer duration and is better tolerated when used in the treatment of inflammatory conditions. However, consult your doctor for the right treatment of your condition.
Predemed 125mg Injection can cause weight gain especially when high doses taken for a long time or repeated short courses are taken. Please consult your doctor if you experience weight gain after taking Predemed 125mg Injection.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medmom Pharmaceuticals LLP
Address: CO 36, Sector 3, Panchkula, Haryana 134109

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Predemed 125mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Why we need a prescription?
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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