Poscosafe Oral Suspension belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat fungal infection. It kills fungi by destroying the fungal cell membrane.
Poscosafe Oral Suspension should be taken in the dose and duration as prescribed by your doctor. They should be swallowed whole and taken with food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse.
The most common side effects of this medicine include headache, diarrhea, feeling sick (nausea), and low potassium level. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and sign of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. The drugs may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Uses of Poscosafe Oral Suspension
Severe fungal infections
Benefits of Poscosafe Oral Suspension
In Severe fungal infections
Poscosafe Oral Suspension is an antifungal medicine. It works by killing and stopping the growth of fungus that is causing the infection. It helps treat severe infections in severely immunocompromised patients, cancer patients, and those undergoing blood transfusion.
The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side effects of Poscosafe Oral Suspension
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Poscosafe
Headache
Rash
Fatigue
Decreased potassium level in blood
Increased liver enzymes
Insomnia (difficulty in sleeping)
Itching
Sleepiness
Taste change
Weakness
Decreased magnesium level in blood
Paresthesia (tingling or pricking sensation)
High blood pressure
Anorectal discomfort
Increased glucose level in blood
Hypoglycemia (low blood glucose level)
Hypotension (low blood pressure)
Anemia (low number of red blood cells)
Low blood platelets
Petechiae (red or purple spot caused by bleeding into the skin)
Vomiting
Cough
Abdominal pain
Constipation
Indigestion
Nosebleeds
Rigors
Swelling of legs
Breathlessness
Decreased appetite
Decreased white blood cell count (neutrophils)
Dizziness
Electrolyte imbalance
Fever
Nausea
Diarrhea
How to use Poscosafe Oral Suspension
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Poscosafe Oral Suspension is to be taken with food.
How Poscosafe Oral Suspension works
Poscosafe Oral Suspension is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Poscosafe Oral Suspension. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Poscosafe Oral Suspension may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Poscosafe Oral Suspension is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Poscosafe Oral Suspension may cause side effects which could affect your ability to drive. As you may feel dizzy, sleepy, or have blurred vision while taking Poscosafe Oral Suspension, which may affect your ability to drive.
Kidney
CAUTION
Poscosafe Oral Suspension should be used with caution in patients with kidney disease. Dose adjustment of Poscosafe Oral Suspension may be needed. Please consult your doctor. Regular monitoring of kidney function tests is advised while taking this medicine. Use of Poscosafe Oral Suspension is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Poscosafe Oral Suspension is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Poscosafe Oral Suspension may not be needed in these patients. Please consult your doctor.
What if you forget to take Poscosafe Oral Suspension?
If you miss a dose of Poscosafe Oral Suspension, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Your doctor has prescribed Poscosafe Oral Suspension to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Take it with food, preferably at the same time every day.
Do not take indigestion remedies (antacids) within two hours of taking Poscosafe Oral Suspension.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal ergosterol synthesis inhibitor
Interaction with drugs
Taking Poscosafe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause serious damage to muscles. Posaconazole may raise blood levels of Lovastatin.
Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, yo... More
Concurrent use may cause muscle damage. Posaconazole may raise blood levels of Simvastatin.
Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor ... More
Concurrent use may cause muscle damage.
Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and ... More
Concurrent use may cause life-threatening disturbances in the heart rhythm. Posaconazole may raise blood levels of Ranolazine.
Do not consume Ranolazine with Posaconazole. If concu... More
I have been experiencing fungal infections, I develop rings and rashes and they all itch like anything. I formed scars because of it. I have been taking Grisovin FP 250 mg however as long I take it I am relieved, even if I miss it for 1 day I start getting fungus back. On top of that Grisovin FP is difficult to find now, please suggest.
Dr. Atul Jain
Dermatology
You are having fungal infections severe, you need to change the medicine by skin specialistCan b prescribed under supervisionMeanwhile apply onabet cream twice a day
Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment
Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Test ? Blood sugar ( Fasting & PP) The treatment has to be complete otherwise it will be recur.
I am regularly using the cream cosmelite But now due to a fungal infection i have to use a antifungal cream fungicros So So i want to know whether i can apply the cream cosmelite after fungicros
Dr. Atul Jain
Dermatology
Pls tell me which part of body have fungal infections
Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching)
What is Poscosafe Oral Suspension and what is it used for?
Poscosafe Oral Suspension belongs to a class of medicines known as antifungal medicines. It is used to treat serious infections caused by various types of fungi such as Aspergillus and Candida, in patients who are at high risk of developing these infections. Poscosafe Oral Suspension is majorly prescribed to severely immunocompromised patients in cases of cancer or those undergoing blood transfusion or chemotherapy.
How to take Poscosafe Oral Suspension?
Poscosafe Oral Suspension should be taken with food to get maximum benefit. Follow your doctor’s instructions carefully and continue taking it in the dose and duration prescribed by the doctor. Do not stop taking it without discussing it with your doctor as it may worsen your symptoms.
I feel better now. Can I stop taking Poscosafe Oral Suspension?
No. You should not stop taking Poscosafe Oral Suspension without discussing it with your doctor even if you feel better. This is because if you stop taking it suddenly, it may worsen your symptoms and your infection may come back. Your doctor will decide for how long you need to continue taking this medicine. Consult your doctor if any of the side effects bother you. If you have completed your course of treatment, your doctor may decrease your dose gradually before taking you off this medicine. Follow your doctor’s instructions carefully.
What if I forget to take a dose of Poscosafe Oral Suspension?
If you have missed a dose of Poscosafe Oral Suspension, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Is Poscosafe Oral Suspension effective?
Poscosafe Oral Suspension is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Poscosafe Oral Suspension too early, the symptoms may return or worsen.
What are the side effects of Poscosafe Oral Suspension?
Some of the common side effects of Poscosafe Oral Suspension are cough, headache, nausea, and vomiting. However, these are usually not bothersome and usually resolve on their own. Please consult your doctor if any of thes side effects worry you or persist for a longer duration.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
Medscape. Posaconazole. [Accessed 29 Mar. 2019] (online) Available from:
Posaconazole. Kenilworth, New Jersey: Schering Plough; 2006. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
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