Posatral 300mg Injection is an antifungal medicine used to prevent and treat severe fungal infections, particularly in people with weakened immune systems. It is commonly prescribed to prevent invasive infections caused by Aspergillus and Candida species and to treat fungal infections of the mouth and throat.
Do not self-administer this medicine. Your doctor or nurse will teach you the correct way of injecting it. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.
The most common side effects of this medicine include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and signs of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Uses of Posatral Injection
Treatment of Severe fungal infections
Benefits of Posatral Injection
In Treatment of Severe fungal infections
Posatral 300mg Injection is an antifungal medicine used to treat serious fungal infections. It is especially beneficial for patients who are severely immunocompromised, such as those with cancer or those undergoing chemotherapy or blood transfusions. This medicine is administered by a doctor or a nurse and should not be self-administered. The dose and duration of treatment will be determined by your doctor based on your condition. It is important to complete the full course of treatment, even if you start feeling better, to ensure the infection is fully cleared and does not return.
Side effects of Posatral Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Posatral
Fever
Decreased potassium level in blood
Diarrhea
Vomiting
Headache
Nausea
Cough
Increased calcium level in blood
How to use Posatral Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Posatral Injection works
Posatral 300mg Injection is an antifungal that works by inhibiting the enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. It disrupts the production of ergosterol, damaging the fungal cell membrane, leading to cell death. This action makes it effective in preventing and treating invasive Aspergillus and Candida infections in immunocompromised patients, as well as treating oropharyngeal candidiasis, including cases resistant to other azoles like itraconazole or fluconazole.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Posatral 300mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Posatral 300mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Posatral 300mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Posatral 300mg Injection may cause side effects which could affect your ability to drive. As you may feel dizzy, sleepy, or have blurred vision while taking Posatral 300mg Injection, which may affect your ability to drive.
Kidney
CAUTION
Posatral 300mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Posatral 300mg Injection may be needed. Please consult your doctor. Regular monitoring of kidney function tests is advised while taking this medicine. Use of Posatral 300mg Injection is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Posatral 300mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Posatral 300mg Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Posatral Injection?
If you miss a dose of Posatral 300mg Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Do not skip any doses and finish the full course of treatment even if you feel better.
It is given as an injection under the supervision of a healthcare professional.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Action Class
Fungal Ergosterol Synthesis Inhibitor
Interaction with drugs
Taking Posatral with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Lovastatin. Posaconazole may raise blood levels of Lovastatin.
Concurren... More
Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Simvastatin. Posaconazole may raise blood levels of Simvastatin.
Concur... More
Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and consult your doctor if you experience the... More
Do not consume Ranolazine with Posaconazole. If concurrent use is essential, watch out for symptoms of Ranolazine side effects such as nausea, vomiting, headache, dizziness, consti... More
I have been experiencing fungal infections, I develop rings and rashes and they all itch like anything. I formed scars because of it. I have been taking Grisovin FP 250 mg however as long I take it I am relieved, even if I miss it for 1 day I start getting fungus back. On top of that Grisovin FP is difficult to find now, please suggest.
Dr. Atul Jain
Dermatology
You are having fungal infections severe, you need to change the medicine by skin specialistCan b prescribed under supervisionMeanwhile apply onabet cream twice a day
I am regularly using the cream cosmelite But now due to a fungal infection i have to use a antifungal cream fungicros So So i want to know whether i can apply the cream cosmelite after fungicros
Dr. Atul Jain
Dermatology
Pls tell me which part of body have fungal infections
Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Test ? Blood sugar ( Fasting & PP) The treatment has to be complete otherwise it will be recur.
Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment
Posatral 300mg Injection is administered under the supervision of a trained healthcare professional or a doctor and should not be self administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Posatral 300mg Injection.
What is Posatral 300mg Injection, and what is it used for?
Posatral 300mg Injection belongs to a class of medicines known as antifungal agents. It is used to treat serious fungal infections caused by organisms such as Aspergillus and Candida, particularly in patients who are at high risk of developing these infections. Posatral 300mg Injection is mainly prescribed to severely immunocompromised individuals, such as those with cancer or those undergoing chemotherapy or blood transfusions.
How is Posatral 300mg Injection administered?
Posatral 300mg Injection is administered under the supervision of a doctor or nurse and should not be self-administered. The dose depends on the condition being treated and will be determined by your doctor. It is important to follow your doctor’s instructions carefully to gain the maximum benefit from Posatral 300mg Injection.
Is Posatral 300mg Injection effective?
Posatral 300mg Injection is effective when used in the dose and duration prescribed by your doctor. Do not stop taking it even if your symptoms improve. Stopping the medication too early may cause the infection to return or worsen.
What are the side effects of Posatral 300mg Injection?
Some common side effects of Posatral 300mg Injection include cough, headache, nausea, and vomiting. These side effects are generally mild and tend to resolve on their own. However, consult your doctor if any of these symptoms persist or cause concern.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
Posaconazole. White House Station, New Jersey: Merck & Co.; 2015. [Accessed 29 Mar. 2019] (online) Available from:
Posaconazole. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2005 [revised 6 Jul. 2018]. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
Country of origin: India Expires on or after: December, 2025
A licensed vendor partner from your nearest location will deliver Posatral 300mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID:[email protected] Phone Number: 0124-4166666 Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India