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Peptimide 100mg Tablet

Rebamipide (100mg)
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Peptimide 100mg Tablet is a medicine used to treat stomach ulcers and gastritis. It increases protective mucus in the stomach, improves blood flow, and reduces inflammation. This helps heal damage caused by acid, irritation, or infection and relieves symptoms like pain, burning, and discomfort.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Dec 2025 | 01:00 AM (IST)
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Peptimide 100mg Tablet
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General Information

The content is shown in English
Peptimide 100mg Tablet image
Peptimide 100mg Tablet image

Product introduction

Take Peptimide 100mg Tablet exactly as prescribed by your doctor, usually once or twice daily. It can be taken with or without food. To get the most benefit, follow your doctor’s instructions carefully and take the medicine regularly without missing doses. In addition to taking Peptimide 100mg Tablet, try to avoid spicy, oily, or acidic foods, limit alcohol intake, and manage stress, as these can irritate the stomach further. Quitting smoking, if you smoke, can also help improve your stomach health.


Some people may experience mild side effects like nausea, constipation, diarrhea, or abdominal discomfort. These usually go away on their own as your body adjusts to the medicine. If the symptoms bother you or persist, talk to your doctor. Serious side effects are rare, but if you experience any unusual symptoms such as severe abdominal pain, allergic reactions, or rash, seek medical help immediately.


Before starting Peptimide 100mg Tablet, tell your doctor if you are pregnant, breastfeeding, or have any liver or kidney problems. Do not take this medicine if you are allergic to rebamipide or any of its ingredients. While on treatment, avoid overuse of painkillers like ibuprofen or aspirin, as they can irritate the stomach lining and slow down healing. Always inform your doctor about any other medications or supplements you are taking to avoid possible interactions.

Uses of Peptimide Tablet

Benefits of Peptimide Tablet

Treatment of Mouth ulcers
Mouth ulcers are small painful sores on inner lips, gums, tongue, roof of the mouth or throat that may interfere with eating, drinking and even talking. Peptimide 100mg Tablet blocks chemicals in our brain that are responsible for pain sensation and inflammation. Therefore it provides relief from pain, discomfort and symptoms of inflammation such as redness or swelling due to mouth ulcers. This makes it easier for you to go about your daily activities. Continue using it as advised by the doctor to get maximum benefit.
Treatment of Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Peptimide 100mg Tablet reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
Treatment of Gastritis
In gastritis, Peptimide 100mg Tablet reduces inflammation of the stomach lining and restores its natural defense by increasing mucus production and suppressing harmful oxidative stress. This helps relieve common symptoms like bloating, burning sensation, nausea, and stomach discomfort. As a result, patients experience better digestion, improved appetite, and overall enhanced comfort, leading to a more balanced and symptom-free lifestyle.

Side effects of Peptimide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Peptimide
  • Abdominal pain
  • Taste change
  • Diarrhea
  • Vomiting
  • Constipation
  • Dizziness
  • Drowsiness
  • Heartburn
  • Decreased white blood cell count (lymphocytes)
  • Menstrual disorder
  • Burping
  • Nausea

How to use Peptimide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Peptimide 100mg Tablet may be taken with or without food.

How Peptimide Tablet works

Rebamipide promotes mucosal healing in stomach ulcers and gastritis by enhancing the production of prostaglandins, stimulating mucus and bicarbonate secretion, and increasing gastric mucosal blood flow. Its antioxidant properties also help reduce inflammation and oxidative damage. Additionally, rebamipide helps in maintaining epithelial integrity and promoting cell regeneration, contributing to mucosal protection and ulcer healing.

Quick tips

  • Peptimide 100mg Tablet can also be taken while you're taking NSAIDs (anti-inflammatory and analgesic drugs) to lower the chance of developing stomach ulcers.
  • Inform your doctor immediately if you develop rashes, itches, and hives.
  • Your doctor may perform routine blood tests to assess the functioning of your liver. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.
  • Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before taking this medicine.
  • Do not stop taking this medicine unless your doctor instructs you to do so.
  • Peptimide 100mg Tablet helps in the treatment of stomach, intestinal and mouth ulcers.
  • It can also be taken while you're taking NSAIDs (anti-inflammatory and analgesic drug) to lowers the chance of developing stomach ulcers.
  • Inform your doctor immediately if you develop symptoms such as rash, itch and hives.
  • Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not stop taking this medicine unless your doctor instructs you to do so.
  • Peptimide 100mg Tablet helps in the treatment of stomach, intestinal and mouth ulcers.
  • It can also be taken while you're taking NSAIDs (anti-inflammatory and analgesic drug) to lowers the chance of developing stomach ulcers.
  • Inform your doctor immediately if you develop symptoms such as rash, itch and hives.
  • Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Peptimide 100mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Peptimide 100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Peptimide 100mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Peptimide 100mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Peptimide 100mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Peptimide 100mg Tablet in patients with liver disease.

Frequently asked questions

Peptimide 100mg Tablet is mainly used for the treatment of gastric ulcers and gastritis. It helps protect the stomach lining, reduces inflammation, and supports the healing of ulcers.
Peptimide 100mg Tablet works by protecting the stomach lining from injury, increasing protective mucus, improving blood flow in the stomach, and reducing harmful substances that can damage the stomach wall. This helps in healing gastritis and gastric ulcers.
Peptimide 100mg Tablet should not be taken by people who have a known allergy to rebamipide or any of its ingredients. If you have had allergic reactions to similar stomach medicines before, inform your doctor.
Yes. Although they are rare, Peptimide 100mg Tablet may cause serious side effects such as allergic reactions (shock, rash, swelling, breathing difficulty), low white blood cell count (leukopenia), low platelets (thrombocytopenia), or liver problems (hepatitis, jaundice). Immediate medical attention is needed if such symptoms appear.
You should contact your doctor if you notice yellowing of the skin or eyes, unusual bleeding, bruising, persistent fever, severe rash, or trouble breathing while taking Peptimide 100mg Tablet.
Elderly patients may be more sensitive to Peptimide 100mg Tablet and are at a higher risk of gastrointestinal issues. Doctors usually prescribe Peptimide 100mg Tablet with caution in older adults and monitor them closely.
Clinical studies show that Peptimide 100mg Tablet is effective and safe for long-term use in treating gastric ulcers and gastritis, with a low recurrence rate of ulcers and good overall tolerability.

Fact Box

Chemical Class

Hippuric acids

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Gastric Mucosal Protective Agents
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cell Salve Pharmaceuticals
Address: C-2/7, Unit No. 12, Palghar Road, Trivedi Nagar, Boisar, Mumbai-401501

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Peptimide 100mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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