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Pentaveri-IV Injection

Pantoprazole (40mg)
Pentaveri-IV Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 Oct 2026 | 01:02 AM (IST)
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Pentaveri-IV Injection 1
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Product introduction

Pentaveri-IV Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.

The most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, stomach pain, and thrombophlebitis (pain, redness, and swelling of the vein). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

Pentaveri-IV Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.

Uses of Pentaveri Injection

Benefits of Pentaveri Injection

Treatment of Acidity
Acidity occurs when excess acid in the stomach causes burning, discomfort, or bloating. Pentaveri-IV Injection helps by reducing acid production in the stomach, offering quick and lasting relief from heartburn and indigestion. Regular use helps maintain a healthy digestive balance and improves comfort after meals.
Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) happens when stomach acid frequently flows back into the food pipe, causing heartburn and irritation. Pentaveri-IV Injection reduces this acid reflux by controlling acid levels, helping the food pipe heal, and preventing further damage. It eases symptoms like burning, chest discomfort, and sour taste, improving daily comfort and sleep quality.
Treatment of Peptic ulcer disease
Peptic ulcers are painful sores in the stomach or intestine caused by excess acid or infection. Pentaveri-IV Injection helps by lowering acid production, allowing the ulcers to heal faster and reducing pain, bloating, and nausea. Continued use helps prevent ulcer recurrence and promotes long-term stomach health.
Treatment of Zollinger-Ellison syndrome
Zollinger–Ellison syndrome is a condition in which tumors in the pancreas or small intestine cause the stomach to produce excessive acid. Pentaveri-IV Injection helps control this acid overproduction, protecting the stomach lining from damage and ulcers. It eases symptoms such as pain and indigestion, improving comfort and quality of life for those living with this condition.

Side effects of Pentaveri Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pentaveri
  • Fever
  • Headache
  • Diarrhea
  • Dizziness
  • Joint pain
  • Nausea
  • Abdominal pain
  • Vomiting
  • Flatulence

How to use Pentaveri Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pentaveri Injection works

Pentaveri-IV Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.

Quick tips

  • Pentaveri-IV Injection is administered into the veins under the supervision of the doctor.
  • Some healthy tips to prevent acidity from happening include avoiding excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, and caffeinated beverages like tea and coffee. Also, avoid alcohol, smoking, and eating late at night.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, rash, or fever. These could be signs of a kidney problem.

Fact Box

Chemical Class

Sulfinylbenzimidazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Proton-Pump Inhibitors
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