Pebact 400mg Tablet

Pefloxacin (400mg)

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Pebact 400mg Tablet is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues, and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

₹41.2 MRP ₹45.149% off

Gurgaon

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General Information

Contains

Pefloxacin (400mg)

Marketer

Sarabhai Chemicals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pebact 400mg Tablet should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

You may experience nausea, headache, and dizziness as side effects of this medicine. These are usually temporary and resolve on their own. Consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.

Uses of Pebact Tablet

Treatment of Bacterial infections

Benefits of Pebact Tablet

Treatment of Bacterial infections
Pebact 400mg Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs, urinary tract, skin, and soft tissues in adults and children. It works by killing and stopping the growth of the bacteria causing the infection.
This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Pebact Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pebact

Nausea
Diarrhea
Headache
Dizziness

How to use Pebact Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pebact 400mg Tablet should be taken with or after food.

How Pebact Tablet works

Pebact 400mg Tablet is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

All substitutes for Pebact 400mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor has prescribed Pebact 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Pebact 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor has prescribed Pebact 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Pebact 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

SAFE

Consuming alcohol with Pebact 400mg Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Pebact 400mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pebact 400mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Pebact 400mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Pebact 400mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Pebact 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pebact with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Pefloxacin. Please consult your doctor. Pefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Aminophylline (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Pefloxacin may raise blood levels of Aminophylline.

Moderate

Mycophenolate mofetil (Oral Route)

Your doctor may monitor the effects of Mycophenolate mofetil along with your overall treatment and adjust the doses as per the observations. Pefloxacin may reduce blood levels of Mycophenolate mofetil.

Moderate

Tizanidine (Oral Route)

Do not consume Tizanidine with Pefloxacin. If concurrent use is essential, watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Pefloxacin may raise blood levels of Tizanidine.

Frequently asked questions

Can the use of Pebact 400mg Tablet cause diarrhea?

Yes, the use of Pebact 400mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Can the use of Pebact 400mg Tablet increase the risk of muscle damage?

Yes, use of Pebact 400mg Tablet is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Pebact 400mg Tablet. Inform your doctor if you feel any kind of muscle pain while using this medicine.

Fact Box

Chemical Class

Quinoline carboxylic acids

Habit Forming

Therapeutic Class

OPHTHAL OTOLOGICALS

Action Class

Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sarabhai Chemicals Ltd
Address: Shantisadan, Mirzapur Road, Ahmedabad -380001

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Pebact 400mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pebact Tablet

Benefits of Pebact Tablet

Side effects of Pebact Tablet

How to use Pebact Tablet

How Pebact Tablet works

All substitutes for Pebact 400mg Tablet

Flox P 400mg Tablet

Cylox 400mg Tablet

Pefan 400mg Tablet

Plx 400mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Aminophylline (Oral Route)

Mycophenolate mofetil (Oral Route)

Tizanidine (Oral Route)

Frequently asked questions

Can the use of Pebact 400mg Tablet cause diarrhea?

Can the use of Pebact 400mg Tablet increase the risk of muscle damage?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests