Paroxib 40mg Injection

Parecoxib (40mg)

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Paroxib 40mg Injection is a pain-relieving medicine. It is used for short-term treatment of postoperative pain. It is given in cases where oral administration of pain killers is unsuitable. It provides only temporary relief and does not cure the condition.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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General Information

Contains

Parecoxib (40mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Paroxib 40mg Injection is generally administered by a healthcare professional. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.

The most common side effect of this medicine is nausea. You may also experience other side effects like changes in blood pressure, back pain, fluid retention, numbness, vomiting, stomach ache, indigestion, constipation, and bloating among others. If any of these side effects persist or get worse, you should let your doctor know.

Before taking it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine.

Uses of Paroxib Injection

Pain relief

Benefits of Paroxib Injection

Pain relief
Paroxib 40mg Injection is used for short term relief of pain in cases where it is not possible to take a pain killer by mouth like in the case of surgery. It works by blocking chemical messengers in the brain that tell us we have pain.

It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Paroxib Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Paroxib

Nausea
Change in blood pressure
Back pain
Numbness
Constipation
Indigestion
Stomach pain
Vomiting
Bloating

How to use Paroxib Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Paroxib Injection works

Paroxib 40mg Injection is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).

Quick tips

Paroxib 40mg Injection helps relieve pain and inflammation.
It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
Do not take Paroxib 40mg Injection if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Paroxib 40mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

Paroxib 40mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Paroxib 40mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Paroxib 40mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Paroxib 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Paroxib 40mg Injection is unsafe to use in patients with liver disease and should be avoided.
Use of Paroxib 40mg Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Paroxib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

What is Paroxib 40mg Injection used for?

Paroxib 40mg Injection is used in adults for short term treatment of pain after surgery

How does Paroxib 40mg Injection work?

Paroxib 40mg Injection belongs to class of medications called cyclo-oxygenase-2 (COX-2) inhibitors. It works by inhibiting the enzyme COX-2 that reduces the formation of chemicals called prostaglandins in the body, thereby reducing pain and inflammation.

Fact Box

Chemical Class

Benzenesulfonamides

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's -Selective COX-2 Inhibitors

References

Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 991-92.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Parecoxib [Package leaflet: Information for the user]. Kent, UK: Pfizer Limited; 2020. [Accessed 17 Dec. 2020] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Paroxib 40mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Paroxib Injection

Benefits of Paroxib Injection

Side effects of Paroxib Injection

How to use Paroxib Injection

How Paroxib Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

What is Paroxib 40mg Injection used for?

How does Paroxib 40mg Injection work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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