Pamserine 250mg Tablet is an antibiotic medicine used to treat drug-resistant tuberculosis. It is generally used in combination with other medicines. This medicine is used when the bacteria have developed resistance to other antibiotics.

Pamserine 250mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the dose and schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back.

The most common side effects of this medicine include memory loss, confusion, insomnia (difficulty sleeping), and dizziness. Inform your doctor if you experience skin rashes, tremors, fits, problems with speech or movement, depression, or other changes in mood, thoughts, or behavior.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Pregnant and breastfeeding mothers should not take this medicine. Your doctor may get regular blood and urine tests while undergoing treatment with this medicine.

Uses of Pamserine Tablet

Tuberculosis (TB)

Benefits of Pamserine Tablet

In Tuberculosis (TB)

Pamserine 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills the infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

How to use Pamserine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pamserine 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pamserine Tablet works

Pamserine 250mg Tablet is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is required for their survival in the human body.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Pamserine 250mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Pamserine 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Pamserine 250mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Pamserine 250mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pamserine 250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pamserine 250mg Tablet may be needed. Please consult your doctor.
Use of Pamserine 250mg Tablet is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Pamserine 250mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Pamserine Tablet?

If you miss a dose of Pamserine 250mg Tablet, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Pamserine 250mg Tablet is used in combination with other medicines for the treatment of tuberculosis.
Take it at the same time every day to help you remember to take it.
Pamserine 250mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid drinking alcohol while taking Pamserine 250mg Tablet as this may worsen the side effects.
During treatment, you will need to have regular blood tests to monitor your kidney and liver function, blood cell counts and the amount of medicine in your blood.
Stop taking Pamserine 250mg Tablet and inform your doctor if you experience skin rashes, headaches, tremor, fits, problems with speech or movement, depression, or other changes in mood, thoughts or behavior.
Do not stop taking this medicine until your doctor tells you to.

Fact Box

Chemical Class

Isoxazolines derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Cell wall active agent

Interaction with drugs

Taking Pamserine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Alfuzosin

Brand(s): Efzu, Alfuzee, Alfuflo

Serious

View all interactions

Patient concerns

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav

Paediatrics

Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.

Extra pulmonary tuberculosis mdr tb for spinal card treatment

Dr. Sunil Sekhri

Diabetology

This needs to be examined and treated in the clinic

Doctor asked me to do TB GOLD test. But there is no lab test on 1mg with so name. Finally I searched for tuberculosis test and I found two test. 1 is Mycobacterium tuberculosis and other 1 is Mycobacterium tuberculosis sputum. Kindly tell me which test is to be selected and proceeded further.

Dr. Gopal Bansilal Samdani

Paediatrics

Please follow your doctors advise as he has clinical examination data with him. He can advise you for place where you can do TB gold

User feedback

What are you using Pamserine Tablet for?

Tuberculosis *

100%

*Tuberculosis (TB)

FAQs

Q. Should Pamserine 250mg Tablet be taken with or without food?

Take Pamserine 250mg Tablet by mouth with or without food as directed by your doctor, usually twice daily (every 12 hours) for the first 2 weeks. Dosage is based on your medical condition and response to treatment. Always follow your doctor's advice while taking this medicine.

Q. Who should not take Pamserine 250mg Tablet?

Pamserine 250mg Tablet should not be taken by people who have a history of seizures or psychiatric disorders, as it may worsen these conditions. It should also be used with caution in people with kidney or liver disease.

Q. Is a prescription required for buying Pamserine 250mg Tablet?

Yes, Pamserine 250mg Tablet is a prescription drug and can only be obtained with a doctor's prescription.

Q. Can Pamserine 250mg Tablet cause anemia?

Yes, Pamserine 250mg Tablet has been associated in a few instances with vitamin B and/or folic–acid deficiency, megaloblastic anemia, and sideroblastic anemia. If evidence of anemia develops during treatment, appropriate studies, and therapy should be instituted.

Q. Can I take alcohol while taking Pamserine 250mg Tablet?

No, avoid alcohol while on treatment with Pamserine 250mg Tablet since it increases the risk of seizures.

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Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1562-63.
Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 789.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 339-40.
DailyMed. Cycloserine. [Accessed 01 Apr. 2019] (online) Available from:
Drugs.com. Cycloserine. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:

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Pamserine 250mg Tablet

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