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Cycloserine is used as second line of treatment for tuberculosis of lungs or any other organs. It is generally given in combination with other anti-tuberculosis medications. Cycloserine is also used for urinary tract infection when other drugs are ineffective.

How it works

Cycloserine is an antibiotic that prevents the infection by inhibiting the essential enzyme required for bacterial growth.

Common side effects

Numbness, Tingling sensation, Abnormal behavior, Acne-like rash, Memory loss, Anemia, Difficulty in speaking, Confusion, Convulsion, Dizziness, Drowsiness, Headache, Insomnia, Irritation, Suicidal behaviors, Vertigo


Expert advice

  • During cycloserine therapy, you should regularly monitor your blood cell counts, kidney and liver functions . 
  • Seek medical attention if you develop any severe allergic skin reactions. 
  • Do not drive or operate machinery as cycloserine may cause dizziness 
  • Do not consume alcohol along with cycloserine as it may worsen the side effects.
  • Do not consume this drug if you are allergic to cycloserine or any of its ingredients.
  • Do not consume this drug if you have severe kidney disorder, history of depression, severe anxiety, psychosis, fits, alcohol dependence, acute porphyria (a rare blood pigment disorder that affects skin and other organs).
  • Tell your doctor if you are pregnant, planning to get pregnant or breastfeeding.

Frequently asked questions


Q. Is cycloserine a beta lactam?
No, cycloserine does not belong to the beta lactam class of antibiotics.
Q. Does cycloserine affect the cell wall?
Cycloserine inhibits bacterial growth by acting on bacterial cell wall. It does not affect human cells.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)