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Paclieva Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Mar 2026 | 11:29 AM (IST)
Paclieva Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.
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Paclieva Injection is currently sold out
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Paclitax 260mg Injection
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Paclieva Injection
Paclieva Injection
vial of 43.4 ml Injection
₹8329
₹9364.69
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Same composition
Paclitax 260mg Injection
Paclitax 260mg Injection
vial of 43.4 ml Injection
by Cipla Ltd
Get by 11pm
₹8408
₹195.53 per ml

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General Information

The content is shown in English
Paclieva Injection image
Paclieva Injection image

Product introduction

It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Paclieva Injection

Breast cancer
Paclieva Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Paclieva Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Paclieva Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Paclieva Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Paclieva Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paclieva
  • Nausea
  • Vomiting
  • Weakness
  • Low blood platelets
  • Rash
  • Upper respiratory tract infection
  • Urinary tract infection
  • Bleeding
  • Anemia (low number of red blood cells)
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Hair loss
  • Decreased blood pressure
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Diarrhea
  • Decreased white blood cell count (neutrophils)

How to use Paclieva Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Paclieva Injection works

Paclieva Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

Quick tips

  • Paclieva Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
  • It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
  • Do not take Paclieva Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
  • Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
  • Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Paclieva Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Paclieva Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Paclieva Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Paclieva Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As there is no reason why you cannot continue driving between courses of Paclieva Injection but you should remember that this medicine contains some alcohol and it may be unwise to drive
Kidney

Kidney

CAUTION
Paclieva Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Paclieva Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Paclieva Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Paclieva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Darunavir (Oral Route)

Caution is advised when taking Paclitaxel with Darunavir. Your doctor may closely monitor the effects of Paclitaxel if used concurrently with Darunavir and adjust the dose if needed.
Severe

Tepotinib (Oral Route)

Do not consume Tepotinib with Paclitaxel. If concurrent use is essential, please consult your doctor. Tepotinib may raise blood levels of Paclitaxel.
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Paclitaxel may reduce efficacy of Cholera Vaccine (Inactivated). Paclitaxel may reduce efficacy of Cholera Vaccine (Inactivated).
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Paclitaxel may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). Paclitaxel may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Paclitaxel may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Paclitaxel may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Frequently asked questions

Yes, Paclieva Injection is generic/ taxane/ FDA approved/ cytotoxic
Paclieva Injection is usually a vesicant (irritant)
Yes, Paclieva Injection is light sensitive/ hydrophobic/ cardiotoxic
Yes, Paclieva Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Paclieva Injection therapy
Paclieva Injection is derived from bark of the Pacific yew, Taxus brevifolia.

Fact Box

Chemical Class

Taxane derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimicrotubule agents- Taxanes

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1707-709.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 949.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1044-46.
  4. Paclitaxel. Hurley, Maidenhead: Hospira UK Ltd.; 2005 [revised Dec. 2016]. [Accessed 24 Jan. 2019] (online) Available from:
  5. Paclitaxel. Summit, New Jersey: Celgene Corporation; 2005 [revised Oct. 2012]. [Accessed 26 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paclitaxel. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Allieva Pharma
Address: 14/16/1, GROUND FLOOR, SAHIBABAD INDUSTRIAL AREA, GHAZIABAD, U.P.-201010

Vendor Details

Country of origin: India
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