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Ostioxen Nasal Solution

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 26 Dec 2025 | 07:44 PM (IST)
Ostioxen Nasal Solution is a medicine used for the treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures. It may also be used for bone pain associated with Paget's disease.
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Ostioxen Nasal Solution
Ostioxen Nasal Solution
bottle of 6 ml Nasal Solution
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General Information

Contains

Calcitonin (Salmon) (200IU)

Marketer

Adexa Pharma Private Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

Preservative

Benzalkonium chloride
The content is shown in English
Ostioxen Nasal Solution image
Ostioxen Nasal Solution image
Ostioxen Nasal Solution image
Ostioxen Nasal Solution image
Ostioxen Nasal Solution image
Ostioxen Nasal Solution image

Product introduction

Ostioxen Nasal Solution should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.

The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Ostioxen Nasal Solution

Benefits of Ostioxen Nasal Solution

Post menopausal osteoporosis
Postmenopausal osteoporosis is a condition where bones become weak and fragile due to decreased estrogen levels after menopause, increasing the risk of fractures. Ostioxen Nasal Solution helps slow bone loss by inhibiting the activity of cells that break down bone, supporting bone strength and reducing fracture risk.
Paget's disease
Paget’s disease is a disorder that causes abnormal bone remodeling, leading to enlarged and weakened bones that may cause pain and deformities. Ostioxen Nasal Solution helps regulate bone turnover by slowing down excessive bone breakdown, reducing pain, and improving bone structure and strength.

Side effects of Ostioxen Nasal Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ostioxen
  • Runny nose
  • Nosebleeds
  • Nasal irritation
  • Back pain
  • Joint pain
  • Headache

How to use Ostioxen Nasal Solution

Use it as advised by your doctor or check the label for directions before use.

How Ostioxen Nasal Solution works

Ostioxen Nasal Solution is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.

Quick tips

  • You have been prescribed Ostioxen Nasal Solution to make your bones stronger, and lower the risk of fractures.
  • It is used in women with osteoporosis who have undergone menopause.
  • It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
  • Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
  • Discontinue Ostioxen Nasal Solution and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ostioxen Nasal Solution during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ostioxen Nasal Solution may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Yes, an unopened bottle of Ostioxen Nasal Solution need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Ostioxen Nasal Solution, store it at room temperature between 15°C and 30°C.
Ostioxen Nasal Solution contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Ostioxen Nasal Solution decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.
Yes, Ostioxen Nasal Solution can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.
Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.
Generally, Ostioxen Nasal Solution is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Ostioxen Nasal Solution causing birth defects or miscarriage in pregnant women. Ostioxen Nasal Solution should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone Resorption Inhibitors- Calcitonin

Related lab tests

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.
  4. Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from:
  5. Calcitonin-salmon [Prescribing Information]. Stein, Switzerland: Novartis Pharma Stein AG; 2017. [Accessed 28 Mar. 2023] (online) Available from:
  6. Calcitonin-salmon. Rockford, IL: Mylan Institutional LLC.; 2017 [Accessed 03 Nov. 2025] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Adexa Pharma Private Ltd
Address: #318, US Complex, Jasola , New Delhi-110076

Vendor Details

Country of origin: India
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