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18 Feb 2020 | 05:26 PM (IST)
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Prescription Required
Store in a refrigerator (2 - 8°C). Do not freeze.


Ostospray is a medicine used for treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures.

Ostospray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.

The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Ostospray Nasal Solution

Side effects of Ostospray Nasal Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ostospray

  • Runny nose
  • Nasal irritation

How to use Ostospray Nasal Solution

Use it as advised by your doctor or check the label for directions before use.

Safety Advice

No interaction found/established
Ostospray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Ostospray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
No interaction found/established
No interaction found/established
No interaction found/established

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
₹421.0/ml of Nasal Solution
Gemitrol NS Nasal Solution
Torrent Pharmaceuticals Ltd
₹309.43/ml of Nasal Solution
save 9%
Calspray Nasal Solution
Macleods Pharmaceuticals Pvt Ltd
₹428.38/ml of Nasal Solution
25% costlier

Quick Tips

  • You have been prescribed Ostospray to make your bones stronger, and lower the risk of fractures.
  • It is used in women with osteoporosis who have undergone menopause.
  • It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
  • Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
  • Discontinue Ostospray and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Fact Box

Chemical Class
Habit Forming
Therapeutic Class

Patient Concerns

I had hot flash, sweating and ganrahat
Dr. Pushkar Mani
Seems like post menopausal syndrome. Visit a gynaecologist.
Ovaries taken out chest pain and intense sweat high heart beats
Dr. Suman Rao
Obstetrics and Gynaecology
These are the symptoms of menopause. Consult a gynaec nearby and discuss about post menopausal therapy
Do you have any questions related to Ostospray ?

User Feedback


Q. Does Ostospray need to be refrigerated?

Yes, an unopened bottle of Ostospray need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Ostospray, store it at room temperature between 15°C and 30°C.

Q. Does Ostospray increase bone density?

Ostospray contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Ostospray decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.

Q. Can Ostospray reduce the calcium levels in blood?

Yes, Ostospray can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.

Q. How should I use Ostospray?

Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.

Q. Is it fine to use Ostospray in pregnant women?

Generally, Ostospray is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Ostospray causing birth defects or miscarriage in pregnant women. Ostospray should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.
  4. Calcitonin. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. Calcitonin. Spring Valley, New York: PAR PHARMACEUTICAL COMPANIES, INC.; 2014. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Expires on or after: January, 2021

A licensed vendor partner from your nearest location will deliver Ostospray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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