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MD Pharmacology, MBBS
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Ostioxen Nasal Solution

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
Preservative
Benzalkonium chloride
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Product introduction

Ostioxen Nasal Solution is a medicine used for the treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures. It may also be used for bone pain associated with Paget's disease.

Ostioxen Nasal Solution should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.

The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.


Uses of Ostioxen Nasal Solution


Side effects of Ostioxen Nasal Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ostioxen

  • Runny nose
  • Nosebleeds
  • Nasal irritation
  • Back pain
  • Joint pain
  • Headache

How to use Ostioxen Nasal Solution

Use it as advised by your doctor or check the label for directions before use.

How Ostioxen Nasal Solution works

Ostioxen Nasal Solution is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.

Safety advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Ostioxen Nasal Solution may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Ostioxen Nasal Solution is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Ostioxen Nasal Solution?

If you miss a dose of Ostioxen Nasal Solution, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Ostioxen Nasal Solution
₹1134/Nasal Solution
Ostospray
Sun Pharmaceutical Industries Ltd
₹1515/nasal solution
28% costlier
Calspray Nasal Solution
Macleods Pharmaceuticals Pvt Ltd
₹2108/nasal solution
79% costlier
Gemitrol NS Nasal Solution
Torrent Pharmaceuticals Ltd
₹2473/nasal solution
110% costlier
Calcisome Nasal Spray
Krinon Remedies Pvt Ltd
₹2088/nasal solution
77% costlier
Knoglina Nasal Spray
Progress Pharma Private Limited
₹2200/nasal solution
86% costlier

Quick tips

  • You have been prescribed Ostioxen Nasal Solution to make your bones stronger, and lower the risk of fractures.
  • It is used in women with osteoporosis who have undergone menopause.
  • It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
  • Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
  • Discontinue Ostioxen Nasal Solution and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Fact Box

Chemical Class
Hormones
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone Resorption Inhibitors- Calcitonin

Patient concerns

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Ovaries taken out chest pain and intense sweat high heart beats
Dr. Suman Rao
Obstetrics and Gynaecology
These are the symptoms of menopause. Consult a gynaec nearby and discuss about post menopausal therapy
Details About osteoporosis treatment
Dr. Akshat Goel
Orthopaedics
Take Calcium and Vitamin-D3 supplements
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FAQs

Does Ostioxen Nasal Solution need to be refrigerated?

Yes, an unopened bottle of Ostioxen Nasal Solution need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Ostioxen Nasal Solution, store it at room temperature between 15°C and 30°C.

Does Ostioxen Nasal Solution increase bone density?

Ostioxen Nasal Solution contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Ostioxen Nasal Solution decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.

Can Ostioxen Nasal Solution reduce the calcium levels in blood?

Yes, Ostioxen Nasal Solution can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.

How should I use Ostioxen Nasal Solution?

Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.

Is it fine to use Ostioxen Nasal Solution in pregnant women?

Generally, Ostioxen Nasal Solution is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Ostioxen Nasal Solution causing birth defects or miscarriage in pregnant women. Ostioxen Nasal Solution should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.
  4. Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. Calcitonin-salmon [Prescribing Information]. Stein, Switzerland: Novartis Pharma Stein AG; 2017. [Accessed 28 Mar. 2023] (online) Available from: External Link

Marketer details

Name: Adexa Pharma Private Ltd
Address: #318, US Complex, Jasola , New Delhi-110076
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

1134
Inclusive of all taxes
MRP1180  4% OFF
3.0 ml in 1 bottle
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