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Oncotar 500mg Injection

Cytarabine (500mg)
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Oncotar 500mg Injection is used to treat some kinds of cancers of blood. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
₹451 MRP ₹4959% off 
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General Information

The content is shown in English
Oncotar 500mg Injection image
Oncotar 500mg Injection image

Product introduction

Oncotar 500mg Injection is given as an injection into the vein or under skin by the healthcare professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include rash, skin ulcer, nausea, vomiting, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice chills, unusual bleeding or bruising and black and tarry stools. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Oncotar Injection

Benefits of Oncotar Injection

Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Oncotar 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Oncotar Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oncotar
  • Rash
  • Skin ulcer
  • Nausea
  • Vomiting
  • Hair loss
  • Abdominal pain
  • Anal ulcers
  • Anemia (low number of red blood cells)
  • Decreased white blood cell count
  • Fever
  • Infection
  • Abnormal liver function
  • Low blood platelets
  • Mouth ulcer
  • Pneumonia
  • Sepsis
  • Mouth sore
  • Stomatitis (Inflammation of the mouth)

How to use Oncotar Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Oncotar Injection works

Oncotar 500mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Quick tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Oncotar 500mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Oncotar 500mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Oncotar 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Oncotar 500mg Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Oncotar 500mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Oncotar 500mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Because of the limited information, a cautious use of Oncotar 500mg Injection is recommended in patients with liver disease.

Interaction with drugs

Taking Oncotar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Cytarabine. Cytarabine may reduce the efficacy of Filgrastim.
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Cytarabine with Cholera Vaccine (Inactivated). If Cholera Vaccine (Inactivated) is essential, ensure a gap of at least 6 months after discontinuing Cytarabine. Please consult your doctor. Cytarabine may reduce efficacy of Cholera Vaccine (Inactivated).
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Cytarabine with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) is essential, ensure a gap of at least 6 months after discontinuing Cytarabine. Please consult your doctor. Cytarabine may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Cytarabine with Purified Vi Polysaccharide Typhoid Vaccine. If Purified Vi Polysaccharide Typhoid Vaccine is essential, ensure a gap of at least 6 months after discontinuing Cytarabine. Please consult your doctor. Cytarabine may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Severe

Pegfilgrastim (Injection Route)

Do not consume Pegfilgrastim from 24 hours before or 24 hours after taking Cytarabine. Cytarabine may reduce the efficacy of Pegfilgrastim.

Frequently asked questions

No. Oncotar 500mg Injection is not a vesicant (irritant) but should be handled with care.
No. Ototoxicity is not reported with use of Oncotar 500mg Injection. However, please consult your doctor if you experience such a side effect.
Yes. Oncotar 500mg Injection is a cytotoxic drug.
Yes. Oncotar 500mg Injection may cause hair loss.
Oncotar 500mg Injection prevents deoxyribonucleic acid (DNA) replication by inhibiting the synthesis of DNA.

Fact Box

Chemical Class

Pyrimidine nucleosides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1698-700.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 947.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 343-44.
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Vendor Details

Country of origin: India
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