Nucala Injection

Mepolizumab (100mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Nucala Injection is a prescription medicine. It is used as an add-on treatment of severe asthma in patients 6 years and older with an eosinophilic phenotype. You should not use this medicine to treat sudden breathing problems.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 15 Apr 2026 | 04:47 PM (IST)

₹79844 MRP ₹79852

Gurgaon

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General Information

Contains

Mepolizumab (100mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Nucala Injection is given by a doctor or a nurse as an injection. You should not self-administer this medicine at home. The dose and duration of the treatment will depend on the severity of your condition. Get the injection regularly and as long as the doctor has prescribed.

The most common side effects of this medicine include headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue). If any of these side effects bother you or get worse, consult with your doctor. They may be able to suggest ways to reduce or treat the side effects.

Do not use this medicine if you are allergic to mepolizumab or any of the ingredients in this medicine. Do not use this medicine if you are taking any oral or inhaled corticosteroid medicines. However, do not stop taking your other asthma medicines unless instructed by your doctor. You should also not use this medicine if you have a parasitic (helminth) infection. Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Nucala Injection

Benefits of Nucala Injection

Treatment and prevention of Asthma
Nucala Injection is used to treat and prevent the symptoms of asthma such as tightness in your chest, wheezing, breathlessness and coughing. It also relieves allergy symptoms like runny nose, watery eyes, sneezing and watery eyes. Nucala Injection works by reducing and preventing swelling and inflammation in your lungs. It may take a few weeks for this medicine to show full effects. In order to prevent future attacks, it is important to identify asthma triggers and avoid them and take your medications as prescribed.

Side effects of Nucala Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nucala

Headache
Injection site reactions (pain, swelling, redness)
Back pain
Fatigue

How to use Nucala Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nucala Injection works

Nucala Injection belongs to a class of medications called monoclonal antibodies. It works by blocking the action of some natural substances in the body that cause the symptoms of asthma such as difficulty breathing, chest pain, cough, and wheezing.

Quick tips

Do not use Nucala Injection to treat sudden breathing problems.
Before taking this medicine, inform your doctor if you are taking any other asthma medications.
If at any time your breathing gets worse, please contact your doctor or nurse for advice straightaway.
Inform your doctor if you have heart problems, high blood pressure, or diabetes.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking, as some anesthetics can interfere with Nucala Injection.
Do not discontinue use without consulting your doctor, even if you feel better.
Do not smoke. Smoking causes irritation and damage to the lungs and will make your condition worse.
Try to keep your regular appointments with your doctor. This is so your doctor can review your condition on a regular basis.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nucala Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Nucala Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nucala Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nucala Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Nucala Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

SAFE IF PRESCRIBED

Nucala Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

What is Nucala Injection used for?

Nucala Injection is used as an add‑on treatment for severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (a rare disease causing blood vessel inflammation), and hypereosinophilic syndrome (high levels of certain white blood cells). It helps control inflammation and reduce flare‑ups in these long‑term conditions when other treatments are not enough.

Can Nucala Injection be used during an asthma or COPD attack?

No. Nucala Injection is not meant to treat sudden breathing problems or asthma attacks. It is used regularly to help prevent future attacks and keep symptoms under control. Always use your quick‑relief inhaler for sudden breathing issues.

Who should not take Nucala Injection?

People who have had allergic reactions to mepolizumab or any of its ingredients should not use Nucala Injection. If you have ever experienced swelling, rash, breathing difficulty, or severe dizziness after receiving Nucala Injection, inform your doctor before taking it again.

What serious side effects of Nucala Injection should I watch out for?

Serious side effects may include allergic or hypersensitivity reactions such as swelling of the face or tongue, hives, low blood pressure, difficulty breathing, or dizziness. Seek immediate medical help if these occur after receiving this medicine.

Can Nucala Injection weaken my immune system or cause infections?

Some people using Nucala Injection have developed herpes zoster (shingles). Your doctor may suggest a shingles vaccine before starting treatment. If you notice any new skin rash or blisters, contact your doctor.

What precautions should I take if I have parasitic infections before using Nucala Injection?

If you have a parasitic (worm) infection, it should be treated before starting Nucala Injection. This medicine may reduce your body’s ability to fight certain parasites. If you get a worm infection while on treatment and it does not clear, your doctor may pause the medicine until it resolves.

Can I stop using my steroid inhaler after starting Nucala Injection?

Do not stop or reduce your steroid medicines suddenly after starting Nucala Injection. Your doctor will guide you if and when it is safe to lower the steroid dose gradually, since stopping too quickly can worsen symptoms or trigger withdrawal effects.

Is Nucala Injection safe for children or older adults?

Nucala Injection is approved for children 6 years and older with severe eosinophilic asthma, and for adults up to 75 years and beyond for other conditions. Studies show it works similarly across age groups, though some older adults may be more sensitive to its effects.

What should I do if I experience pain, redness, or swelling at the Nucala Injection injection site?

Mild pain, redness, or swelling at the injection site is common and usually goes away within a few days. If the area becomes very painful, itchy, or swollen, or if you develop a rash elsewhere, contact your doctor, as it could be an allergic reaction.

Can I receive vaccines while taking Nucala Injection?

Yes. You can usually receive vaccines while using Nucala Injection, but some vaccines, such as live vaccines, may require caution. Always check with your doctor before getting vaccinated, especially if it is a new vaccine or booster.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

RESPIRATORY

Action Class

Monoclonal Antibodies (mAbs)

Related lab tests

Absolute Eosinophil Count

Complete Blood Count

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: United kingdom

Lab tests offered by us

Why we need a prescription?

Nucala Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Nucala Injection

Benefits of Nucala Injection

Side effects of Nucala Injection

How to use Nucala Injection

How Nucala Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Nucala Injection used for?

Can Nucala Injection be used during an asthma or COPD attack?

Who should not take Nucala Injection?

What serious side effects of Nucala Injection should I watch out for?

Can Nucala Injection weaken my immune system or cause infections?

What precautions should I take if I have parasitic infections before using Nucala Injection?

Can I stop using my steroid inhaler after starting Nucala Injection?

Is Nucala Injection safe for children or older adults?

What should I do if I experience pain, redness, or swelling at the Nucala Injection injection site?

Can I receive vaccines while taking Nucala Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Absolute Eosinophil Count

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests