Noxafil 100mg Tablet DR
Prescription Required
Product introduction
Noxafil 100mg Tablet DR is an antifungal medicine used to prevent and treat severe fungal infections, particularly in people with weakened immune systems. It is commonly prescribed to prevent invasive infections caused by Aspergillus and Candida species and to treat fungal infections of the mouth and throat.
Noxafil 100mg Tablet DR should be taken with food. Take it exactly in the dose and duration prescribed by your doctor. Do not skip doses and complete the full course of treatment, even if you start to feel better. While taking this medicine, follow good hygiene practices and avoid contact with people who have infections, especially if your immune system is weak.
The most common side effects of Noxafil 100mg Tablet DR include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia (low potassium level). These are not usually serious, but let your doctor know if any of these side effects persist or worsen. They may be able to guide you on how to manage or prevent the side effects.
Talk to your doctor before taking Noxafil 100mg Tablet DR if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). If your course of treatment is for more than a month, your doctor may want to check your liver and potassium levels by testing your blood. Pregnant and breastfeeding women should not take this medicine without consulting their doctors.
Uses of Noxafil Tablet DR
- Treatment of Severe fungal infections
Benefits of Noxafil Tablet DR
In Treatment of Severe fungal infections
Noxafil 100mg Tablet DR is an antifungal medicine used to treat serious fungal infections. It is especially beneficial for patients who are severely immunocompromised, such as those with cancer or those undergoing chemotherapy or blood transfusions. This medicine is administered by a doctor or a nurse and should not be self-administered. The dose and duration of treatment will be determined by your doctor based on your condition. It is important to complete the full course of treatment, even if you start feeling better, to ensure the infection is fully cleared and does not return.
Side effects of Noxafil Tablet DR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Noxafil
- Decreased potassium level in blood
- Cough
- Vomiting
- Headache
- Fever
- Nausea
- Diarrhea
How to use Noxafil Tablet DR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Noxafil 100mg Tablet DR is to be taken with food.
How Noxafil Tablet DR works
Noxafil 100mg Tablet DR is an antifungal that works by inhibiting the enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. It disrupts the production of ergosterol, damaging the fungal cell membrane, leading to cell death. This action makes it effective in preventing and treating invasive Aspergillus and Candida infections in immunocompromised patients, as well as treating oropharyngeal candidiasis, including cases resistant to other azoles like itraconazole or fluconazole.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Noxafil 100mg Tablet DR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Noxafil 100mg Tablet DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Noxafil 100mg Tablet DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Noxafil 100mg Tablet DR may cause side effects which could affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Noxafil 100mg Tablet DR, which may affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Noxafil 100mg Tablet DR, which may affect your ability to drive.
Kidney
CAUTION
Noxafil 100mg Tablet DR should be used with caution in patients with kidney disease. Dose adjustment of Noxafil 100mg Tablet DR may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Noxafil 100mg Tablet DR is not recommended in patients with moderate to severe kidney disease.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Noxafil 100mg Tablet DR is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Noxafil 100mg Tablet DR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Noxafil 100mg Tablet DR may not be needed in these patients. Please consult your doctor.
What if you forget to take Noxafil Tablet DR?
If you miss a dose of Noxafil 100mg Tablet DR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Take Noxafil 100mg Tablet DR with food to enhance the absorption, preferably at the same time every day.
- Do not take indigestion remedies (antacids) within two hours of taking Noxafil 100mg Tablet DR.
- Your doctor may check your liver function before starting treatment and regularly thereafter.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal Ergosterol Synthesis Inhibitor
Interaction with drugs
Taking Noxafil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Lovastatin. Posaconazole may raise blood levels of Lovastatin.
Concurren
Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Simvastatin. Posaconazole may raise blood levels of Simvastatin.
Concur
Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and consult your doctor if you experience the
Do not consume Pimozide with Posaconazole.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Ranolazine with Posaconazole. If concurrent use is essential, watch out for symptoms of Ranolazine side effects such as nausea, vomiting, headache, dizziness, consti
Patient concerns
FAQs
What is Noxafil 100mg Tablet DR, and what is it used for?
Noxafil 100mg Tablet DR belongs to a class of medicines known as antifungal agents. It is used to treat serious fungal infections caused by organisms such as Aspergillus and Candida, particularly in patients who are at high risk of developing these infections. Noxafil 100mg Tablet DR is mainly prescribed to severely immunocompromised individuals, such as those with cancer or those undergoing chemotherapy or blood transfusions.
How is Noxafil 100mg Tablet DR taken?
Take Noxafil 100mg Tablet DR in the dose and duration prescribed by the doctor. The dose depends on the condition being treated and will be determined by your doctor. It is important to follow your doctor’s instructions carefully to gain the maximum benefit from Noxafil 100mg Tablet DR. Do not skip any doses and make sure to complete the full course of treatment.
Is Noxafil 100mg Tablet DR effective?
Noxafil 100mg Tablet DR is effective when used in the dose and duration prescribed by your doctor. Do not stop taking it even if your symptoms improve. Stopping the medication too early may cause the infection to return or worsen.
What are the side effects of Noxafil 100mg Tablet DR?
Some common side effects of Noxafil 100mg Tablet DR include cough, headache, nausea, and vomiting. These side effects are generally mild and tend to resolve on their own. However, consult your doctor if any of these symptoms persist or cause concern.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
- Posaconazole. Kenilworth, New Jersey: Schering Plough; 2006. [Accessed 29 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
- Noxafil [Prescribing Information]. Whitehouse Station, NJ: Merck & Co., Inc.; 2015. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Country of origin: India
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