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Nitrogesic Rectal Ointment

Prescription Required



Nitrogesic Rectal Ointment is a medicine used for relieving the pain associated with anal fissures (tear in the lining of the anus). It improves blood flow and reduces the pressure in anal tissues.

Nitrogesic Rectal Ointment promotes healing of fissures and provides pain relief. It is for external use only. It is advised to use it in the dose and duration as advised by your doctor. Clean and dry the affected area and gently apply it over the affected area.

The common side effects of this medicine include headache, dizziness, and nausea. You may also experience slight anal irritation on application of the medicine. This is temporary and usually resolves on its own in some time. You should consult your doctor if it does not resolve or persists for a longer duration.

Do not use the medicine if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.

Uses of Nitrogesic Rectal Ointment

Side effects of Nitrogesic Rectal Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nitrogesic

  • Headache
  • Dizziness
  • Nausea

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.

Safety Advice

No interaction found/established
Nitrogesic Rectal Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Nitrogesic Rectal Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
No interaction found/established
There is limited information available on the use of Nitrogesic Rectal Ointment in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Nitrogesic Rectal Ointment in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Nitrogesic Rectal Ointment
₹3.6/gm of Rectal Ointment
Myovin Rectal Ointment
Cadila Pharmaceuticals Ltd
₹1.13/gm of Rectal Ointment
save 69%

Quick Tips

  • Nitrogesic Rectal Ointment may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Do not consume alcohol while taking Nitrogesic Rectal Ointment as it may cause increased dizziness.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • You may develop tolerance to Nitrogesic Rectal Ointment with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrogesic Rectal Ointment as it may cause low blood pressure.

Fact Box

Chemical Class
Nitrates {Short acting}
Habit Forming

Interaction with Drugs

Taking Nitrogesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Joy On, One Up, Yuvagra
Brand(s): Suvida Force, Tadagra, Tadafun
Brand(s): Udzire
Brand(s): Edafil

Patient Concerns

Patient suffering from anal fissure
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Consult rectal surgeon please
Fissure and fistula of anal region Fissure and fistula of anal and rectal region
Dr. Pushkar Mani
refer to surgeon again
Do you have any questions related to Nitrogesic Rectal Ointment ?

User Feedback


Q. Does Nitrogesic cure anal fissures?

No, Nitrogesic does not cure fissures. It reduces inflammation of mucous membrane and skin. It also helps to reduce irritation, pain and itching associated with anal fissures, thus providing symptomatic relief.

Q. Why is my fissure not healing?

Fissures usually heal within a few weeks. But if your fissures do not improve then this could be due to the poor oxygen supply to the area being treated which further slows down the healing process. As a result, these fissures fail to heal and continue to get worse. You should consult a doctor immediately if you have been facing issues for a duration longer than a few weeks.

Q. What should I eat and avoid in fissure?

You must take a fiber-rich diet such as vegetables, fresh fruits and whole grains if you have fissures. Drink plenty of water and avoid taking alcohol. This will ensure that your stools are soft and easy to pass. You can also take laxatives or fiber supplements if you are facing issues with digestion. Your doctor will suggest ways to avoid constipation and thereby promote healing of fissures.

Q. Can spicy food cause fissures?

No, spicy foods do not cause fissures. But, they can irritate the fissures and worsen your symptoms. Therefore, it is advised that you avoid taking spicy foods if you are facing issues with your fissures.

Q. How do you use Nitrogesic cream?

Follow your doctor’s instructions before using Nitrogesic. Apply a small amount of the ointment to the affected rectal area as directed. If this is to be used inside the rectum, attach the rectal applicator onto the tube. Insert the applicator gently and to full extent into the rectum. Gently squeeze the tube to deliver the medication while withdrawing it.

Q. How long does it take to heal fissures?

Fissures usually heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are termed as chronic fissures. Please consult your doctor without any delay if you have been noticing fissures for longer than 4 weeks.

Q. What precautions do I need to take while using Nitrogesic?

Be careful not to get Nitrogesic into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Nitrogesic if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Nitrogesic with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive. Pregnant and breastfeeding mothers should use Nitrogesic only if prescribed by the doctor.

Related Products


1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
  2. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
  4. Glyceryl trinitrate. Galashiels, Scotland: Kyowa Kirin Ltd.; 2009 [revised May 2016]. [Accessed 26 Jun. 2020] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Country of Origin: India
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