Nitrocin Spray

Nitroglycerin (25mg)

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Nitrocin Spray is used to treat and prevent heart-related chest pain (angina). Angina occurs when the heart muscle is not getting enough blood. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Mar 2026 | 12:42 PM (IST)

₹115 MRP ₹125.118% off

Gurgaon

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Nitrocin Spray should be taken at the first sign of chest pain. It should be used in the dose and duration as advised by your doctor. Seek medical help immediately if your chest pain continues for more than 15 minutes. Some people may be advised to use this medicine prior to any exertional activity or exercise, which may precipitate angina.

The most common side effect of this medicine is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall, and other side effects such as flushing, weakness, and increased heart rate.

Do not use this medicine if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.

Uses of Nitrocin Sublingual Spray

Angina (heart-related chest pain)

Benefits of Nitrocin Sublingual Spray

Angina (heart-related chest pain)
Angina is chest pain caused by reduced blood flow to the heart muscle, often due to narrowed arteries. Nitrocin Spray works by relaxing and widening blood vessels, improving blood flow to the heart. This helps relieve chest pain quickly, reduces the heart’s workload, and lowers the risk of heart-related complications.

Side effects of Nitrocin Sublingual Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nitrocin

Weakness
Dizziness
Headache
Increased heart rate
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nitrocin Sublingual Spray

To use the spray, open your mouth, lift your tongue and press the bottle button down firmly to spray the medicine under your tongue. Close your mouth after you have sprayed the dose. You should not shake the bottle before use. Nitrocin Spray may be taken with or without food.

How Nitrocin Sublingual Spray works

Nitrocin Spray is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload. It thus prevents/treats attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.

Quick tips

Nitrocin Spray may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nitrocin Spray as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Nitrocin Spray with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrocin Spray as it may cause low blood pressure.
You have been prescribed Nitrocin Spray for the prevention and treatment of heart-related chest pain (angina).
Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
Nitrocin Spray may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nitrocin Spray as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Nitrocin Spray with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrocin Spray as it may cause low blood pressure.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Nitrocin Spray.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Nitrocin Spray during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nitrocin Spray during breastfeeding is not available. Please consult your doctor.

Driving

CAUTION

Nitrocin Spray may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Nitrocin Spray is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Nitrocin Spray in patients with liver disease.

Interaction with drugs

Taking Nitrocin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Sildenafil (Oral Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Tadalafil (Oral Route)

Do not consume Tadalafil with Nitroglycerin. If Tadalafil is essential, ensure a gap of at least 48 hours between taking Tadalafil and Nitroglycerin.

Life-threatening

Sildenafil (Oral Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Sildenafil (Injection Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Sildenafil (Injection Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Frequently asked questions

How long does it take for Nitrocin Spray to act?

Nitrocin Spray starts working very quickly. If the medicine is kept under the tongue, the effect starts 1-3 minutes later and reaches its maximum within 5 minutes.

What effect does Nitrocin Spray have on blood pressure?

Nitrocin Spray decreases the blood pressure by relaxing the blood vessels, but is not recommended for the treatment of high blood pressure. The drop in blood pressure may cause lightheadedness, especially when changing your position suddenly.

Does the effect of Nitrocin Spray wear off after sometime?

Yes, excessive use of Nitrocin Spray may cause tolerance which means that Nitrocin Spray may lose its effectiveness on you. Therefore, usually the doctors prescribe the smallest dose required for effective relief of acute angina attack. This helps maintain the effectiveness of Nitrocin Spray.

What does too much Nitrocin Spray do?

Excess Nitrocin Spray may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.

Can I stop using Nitrocin Spray as I feel better now?

Stopping Nitrocin Spray suddenly may bring on attacks of angina, especially if you have been using it for several weeks or more. Talk to your doctor who will advise you to reduce the dose gradually over 4 to 6 weeks before you stop using it completely.

Does Nitrocin Spray stop heart attacks?

Nitrocin Spray is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease the blood vessels (coronary arteries) which supply blood to the heart become narrowed because of which the heart has to work harder to get enough oxygen. Nitrocin Spray prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.

Can I take sildenafil if I am taking Nitrocin Spray?

No, you should not take Nitrocin Spray if you have taken sildenafil. Taking these two medicines together may increase the risk of excessive fall in blood pressure, which is hazardous. Maintain a gap of at least 24 hours if you have to use Nitrocin Spray after taking sildenafil.

Fact Box

Chemical Class

Alkyl nitrates

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Nitric Oxide (NO) Donors

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
Nitroglycerin Sublingual Tablets. New York, New York: Parke-Davis; 2014. [Accessed 20 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Glyceryl trinitrate [Package leaflet: Information for the user]. Łyszkowice, Poland: Orifarm Manufacturing Poland Sp. z o.o.; 2022. [Accessed 03 Aug. 2023] (online) Available from:

User feedback

What are you using Nitrocin Sublingual Spray for?

Others

67%

Angina (heart-related chest pain)

33%

How much was the improvement?

Poor

67%

Average

33%

What were the side-effects while using Nitrocin Spray?

Headache

50%

Flushing (sense of warmth in the face, ears, neck and trunk)

50%

Please rate Nitrocin Spray on price

Average

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India

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Nitrocin Spray

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Nitrocin Sublingual Spray

Benefits of Nitrocin Sublingual Spray

Side effects of Nitrocin Sublingual Spray

How to use Nitrocin Sublingual Spray

How Nitrocin Sublingual Spray works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Sildenafil (Oral Route)

Tadalafil (Oral Route)

Sildenafil (Oral Route)

Sildenafil (Injection Route)

Sildenafil (Injection Route)

Frequently asked questions

How long does it take for Nitrocin Spray to act?

What effect does Nitrocin Spray have on blood pressure?

Does the effect of Nitrocin Spray wear off after sometime?

What does too much Nitrocin Spray do?

Can I stop using Nitrocin Spray as I feel better now?

Does Nitrocin Spray stop heart attacks?

Can I take sildenafil if I am taking Nitrocin Spray?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Nitrocin Sublingual Spray for?

How much was the improvement?

What were the side-effects while using Nitrocin Spray?

Please rate Nitrocin Spray on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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