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Nikos 5 Tablet

Nicorandil (5mg)

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Stored between 2-8°C

Nikos 5 Tablet is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are either not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Mar 2026 | 01:06 PM (IST)

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General Information

Contains

Nicorandil (5mg)

Marketer

Lloyd Healthcare Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Nikos 5 Tablet may be taken with or without food. It should be swallowed whole with water. Take this medicine regularly and at about the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. Do not stop taking it without talking to our doctor as sudden withdrawal may cause your chest pain to come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, exercising regularly, and managing stress.

The most common side effect of this medicine is headache, especially during the first few days of treatment. This usually improves within a week. However, drinking plenty of fluids and avoiding alcohol may help. Other common side effects include dizziness or weakness, nausea, and flushing (sense of warmth in the face, ears, neck, and trunk). Talk to your doctor if these bother you or do not go away.

Nikos 5 Tablet may not be suitable for some people. Inform your doctor if you have a history of low blood pressure or heart failure. Also let your doctor know about all other medications that you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. Nikos 5 Tablet is not usually recommended during pregnancy or breastfeeding.

Uses of Nikos Tablet

Treatment of Angina (heart-related chest pain)

Benefits of Nikos Tablet

Treatment of Angina (heart-related chest pain)
Nikos 5 Tablet helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by the narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nikos 5 Tablet relaxes and widens the blood vessels so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes thereby improving your ability to exercise and go about your daily life more easily. This medicine needs to be taken regularly to be effective so keep taking it even if you are not having any angina symptoms.

Side effects of Nikos Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nikos

Headache
Nausea
Vomiting
Weakness
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nikos Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nikos 5 Tablet may be taken with or without food.

How Nikos Tablet works

Nikos 5 Tablet is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. It also relaxes coronary artery (that carries blood to heart). This reduces the frequency and severity of angina attacks.

All substitutes for Nikos 5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You must continue to take it as advised, usually for a long time.
Nikos 5 Tablet may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Nikos 5 Tablet may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
Do not consume alcohol while taking Nikos 5 Tablet as that may cause increased dizziness.
Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nikos 5 Tablet as it may cause low blood pressure.
Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Nikos 5 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nikos 5 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nikos 5 Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nikos 5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Nikos 5 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Nikos 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Nikos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Sildenafil (Oral Route)

Do not consume Sildenafil with Nicorandil.

Severe

Tadalafil (Oral Route)

Do not consume Tadalafil with Nicorandil.

Severe

Vardenafil (Oral Route)

Do not consume Vardenafil with Nicorandil.

Severe

Sildenafil (Oral Route)

Do not consume Sildenafil with Nicorandil.

Severe

Sildenafil (Injection Route)

Do not consume Sildenafil with Nicorandil.

Frequently asked questions

What class of drug is Nikos 5 Tablet and what is it used for?

Nikos 5 Tablet belongs to a class of medicines known as “potassium channel openers”. It causes widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta-blockers, calcium channel antagonist) meant for angina.

Can I stop taking Nikos 5 Tablet?

No, you should not stop taking Nikos 5 Tablet without speaking to your doctor first. If you stop Nikos 5 Tablet suddenly, your anginal pain may recur. Talk to your doctor if you are experiencing any side effects.

For how long do I need to continue Nikos 5 Tablet?

Continue taking your medicine for as long as your doctor tells you. Nikos 5 Tablet is generally prescribed for a long term. You may even need to take it for the rest of your life.

What if somebody accidentally takes excess of Nikos 5 Tablet?

He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.

Can I take Nikos 5 Tablet if I am taking aspirin?

You should avoid taking Nikos 5 Tablet and aspirin together. Taking the two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor, If you notice blood in your stool or vomit while using Nikos 5 Tablet.

Who should not use Nikos 5 Tablet?

People who are allergic to Nikos 5 Tablet or any of its ingredients should avoid using this medicine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Nikos 5 Tablet. Additionally, patients taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil, and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat) should not use the medication. Your blood pressure may be affected if these medicines are taken with Nikos 5 Tablet or if you have low blood volume.

Can Nikos 5 Tablet affect my sex life?

No, Nikos 5 Tablet does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Nikos 5 Tablet. Taking them together can lead to a serious drop in your blood pressure.

Fact Box

Chemical Class

Nicotinamides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Potassium Channel Openers (KCOs)

References

Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 57.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 198.
Nicorandil. Macquarie Park, New South Wales: Sanofi-Aventis Australia Pty Ltd.; 2017. [Accessed 18 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Nicorandil. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 05 Jan. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lloyd Healthcare Pvt Ltd
Address: 702, Balaji Business Park, Andheri Kurla Road, Marol Naka, Andheri East, Gamdevi, Marol, Andheri East, Mumbai, Maharashtra 400059

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nikos 5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Nikos 5 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Nikos Tablet

Benefits of Nikos Tablet

Side effects of Nikos Tablet

How to use Nikos Tablet

How Nikos Tablet works

All substitutes for Nikos 5 Tablet

EL-Nico 5 Tablet

Nikoran 5 Tablet

KORANdil 5 Tablet

K-Cor 5 Tablet

Nicoduce 5 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Sildenafil (Oral Route)

Tadalafil (Oral Route)

Vardenafil (Oral Route)

Sildenafil (Oral Route)

Sildenafil (Injection Route)

Frequently asked questions

What class of drug is Nikos 5 Tablet and what is it used for?

Can I stop taking Nikos 5 Tablet?

For how long do I need to continue Nikos 5 Tablet?

What if somebody accidentally takes excess of Nikos 5 Tablet?

Can I take Nikos 5 Tablet if I am taking aspirin?

Who should not use Nikos 5 Tablet?

Can Nikos 5 Tablet affect my sex life?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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