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Nicorandil

Information

Uses

Nicorandil is used in the treatment of angina

How it works

Nicorandil reduces the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.

Common side effects

Nausea, Vomiting, Headache, Weakness, Dizziness, Flushing (sense of warmth in the face, ears, neck and trunk)

Available Medicine

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  • ₹71 to ₹373
    Torrent Pharmaceuticals Ltd
    6 variant(s)
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    Sun Pharmaceutical Industries Ltd
    2 variant(s)
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    Lupin Ltd
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    Macleods Pharmaceuticals Pvt Ltd
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    Abbott India Ltd
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    Emcure Pharmaceuticals Ltd
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    Zydus Cadila
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    Nouveau Medicament Pvt Ltd
    2 variant(s)
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    Emcure Pharmaceuticals Ltd
    2 variant(s)
  • ₹185 to ₹250
    Medreich Lifecare Ltd
    2 variant(s)

Expert advice

Do not start or continue nicorandil and consult your doctor:
  • If you have severe mouth sores (ulceration).
  • If you are taking medication to lower blood pressure.
  • If your taking medication to treat inflammation (corticosteroids).
  • If you have blood volume depletion or fluid in the lungs (acute pulmonary edema).
The tablets are sensitive to moisture; hence the patients should be advised to keep the tablets in their blister until intake. Nicorandil tablets are not suitable to take to treat an angina attack. Blood pressure-lowering effects of nicorandil can reduce the ability to drive or to use machines. This effect can be increased in conjunction with alcohol. Caution should be maintained while driving or operating heavy machinery.

Frequently asked questions

Nicorandil

Q.

What is nicorandil?
Nicorandil belongs to the class of medicines known as potassium channel activator with nitric oxide-mediated vasodilating properties.

Q.

What is nicorandil used for?
Nicorandil is used in the prevention and treatment of chronic stable angina and in decreasing the risk of acute coronary syndrome in patients with chronic stable angina with risk factors.

Q.

Can nicorandil used for lowering blood pressure?
No, it is not used to lower blood pressure. However, concomitant administration with blood pressure lowering drugs (vasodilators, alcohol) may decrease the blood pressure. Patients consult your doctor for the treatment of your high blood pressure.

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Q.

Does nicorandil cause headache?
Yes, headache is a common side effect with nicorandil. Talk to your doctor if you experience this side effect while taking this medicine.

Q.

Is nicorandil an ACE inhibitor?
No, nicorandil is not an ACE (angiotensin-converting enzyme) inhibitor. It is a potassium channel opener which also has nitric oxide-mediated vasodilatory property.

Q.

Is nicorandil a beta blocker?
No, nicorandil is not a beta blocker. It is a potassium channel opener which also has nitric oxide-mediated vasodilatory property.

Q.

Is nicorandil a calcium channel blocker?
No, nicorandil is not a calcium channel blocker. It is a potassium channel opener which also has nitric oxide-mediated vasodilatory property.

Q.

Is nicorandil a nitrate?
Nicorandil is a potassium channel opener which also has a nitrate moiety in its structure. It acts by dilating your blood vessels and is used in the treatment of conditions like angina pectoris.

Q.

Nicorandil is used for?
Nicorandil is a potassium channel opener and also has nitrate mediated action. It is used for conditions like chronic stable angina and for risk reduction in acute coronary syndromes.

Q.

Why is nicorandil not available in the US?
Nicorandil is not yet approved by the FDA for use in the United States of America.

Q.

Does nicorandil lower blood pressure?
Nicorandil may lower the blood pressure, especially in hypertensive patients. Hence it should be used with caution when used along with other antihypertensive drugs. Please consult your doctor if you are experiencing low blood pressure while taking nicorandil.

Q.

Does nicorandil work?
Nicorandil is a potassium channel opener and also has nitrate mediated action. It acts by relaxing the vascular smooth muscles and reducing the workload of the heart. It is used in the treatment of chronic angina.

Q.

How long does nicorandil take to work?
Nicorandil is rapidly absorbed after oral intake and attains a peak plasma concentration between thirty to sixty minutes.


Content on this page was last updated on 31 March, 2017, by Dr. Varun Gupta (MD Pharmacology)