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Nicorandil is used in the treatment of angina (chest pain), heart failure and increased blood pressure

How it works

Nicorandil works by relaxing blood vessel which lower blood pressure and allows more blood and oxygen to reach the heart and other organs.

Common side effects

Nausea, Vomiting, Headache, Weakness, Increased heart rate, Flushing, Dizziness

Available Medicine

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Expert advice

Do not start or continue nicorandil and consult your doctor:
  • If you have severe mouth sores (ulceration).
  • If you are taking medication to lower blood pressure.
  • If your taking medication to treat inflammation (corticosteroids).
  • If you have blood volume depletion or fluid in the lungs (acute pulmonary edema).
The tablets are sensitive to moisture; hence the patients should be advised to keep the tablets in their blister until intake. Nicorandil tablets are not suitable to take to treat an angina attack. Blood pressure-lowering effects of nicorandil can reduce the ability to drive or to use machines. This effect can be increased in conjunction with alcohol. Caution should be maintained while driving or operating heavy machinery.

Frequently asked questions



Is nicorandil FDA Approved?
Yes, it is FDA approved for prevention and treatment of long term chronic stable angina (sensation of pressure, squeezing, or pain in the chest due to insufficient supply of blood to the muscles of the heart) and acute coronary syndrome


Is nicorandil a beta blocker/calcium channel blocker/angiotensin converting enzyme inhibitor/nitrate?
No, nicorandil belong to class of medication called as potassium channel activator


What is nicorandil and for what treatment it is used for?
Nicorandil belong to class of medication called as potassium channel activator. It is used in prevention and treatment of chronic stable angina and acute coronary syndrome

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Can nicorandil used for lowering blood pressure?
No, it is not used to lower blood pressure. However, concomitant administration with blood pressure lowering drugs (vasodilators, alcohol. Tricyclic antidepressants ) may decrease the blood pressure of hypotensive patients. Patients should consult doctors regarding the possible side effects


Does nicorandil cause headache?
Yes, headache is the most common side effect with nicorandil. Patients should consult doctors regarding the possible side effects.

Content on this page was last updated on 08 February, 2017, by Dr. Varun Gupta (MD Pharmacology)