Nikmef 50mg Syrup

Mefenamic Acid (50mg)

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Nikmef 50mg Syrup is used in the treatment of moderate to severe pain conditions like menstrual pain, headache, muscle pain, joint pain, or dental pain. It effectively alleviates pain and inflammation.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 05:34 PM (IST)

₹44.7 MRP ₹50.6312% off

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General Information

Contains

Mefenamic Acid (50mg)

Marketer

Mgee Healthcare

Storage

Store below 30°C

The content is shown in English

Product introduction

Nikmef 50mg Syrup should be taken with food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have asthma, have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Nikmef Syrup

Pain relief

Benefits of Nikmef Syrup

Pain relief
Nikmef 50mg Syrup is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Nikmef Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nikmef

Vomiting
Stomach pain
Nausea
Headache
Dizziness

How to use Nikmef Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Nikmef 50mg Syrup is to be taken with food.

How Nikmef Syrup works

Nikmef 50mg Syrup is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick tips

It should be taken with food or milk to avoid getting an upset stomach.
It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
Nikmef 50mg Syrup can raise your risk of blood clots, heart attack, or a stroke.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nikmef 50mg Syrup.

Pregnancy

CONSULT YOUR DOCTOR

Nikmef 50mg Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Nikmef 50mg Syrup is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Nikmef 50mg Syrup may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nikmef 50mg Syrup should be used with caution in patients with kidney disease. Dose adjustment of Nikmef 50mg Syrup may be needed. Please consult your doctor.
Use of Nikmef 50mg Syrup is not recommended in patients with severe kidney disease.

Liver

CAUTION

Nikmef 50mg Syrup should be used with caution in patients with liver disease. Dose adjustment of Nikmef 50mg Syrup may be needed. Please consult your doctor.

Interaction with drugs

Taking Nikmef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Is mefenamic acid an antibiotic/ contain codeine?

No. Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat mild to moderate pain conditions and fever. It not an antibiotic and does not contain codeine

Is Nikmef 50mg Syrup a painkiller?

Yes. Nikmef 50mg Syrup is mild to moderate painkiller drug

Is Nikmef 50mg Syrup safe?

Nikmef 50mg Syrup is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is Nikmef 50mg Syrup good for toothache/ for back pain/ headache?

Yes, Nikmef 50mg Syrup can be used to relieve dental pain, back pain and headache

Does Nikmef 50mg Syrup stop periods/ stop bleeding?

Nikmef 50mg Syrup is used for relieving pain that happens before or during a menstrual period. It does not stop periods or bleeding. Always consult your doctor regarding its use

Can I take mefenamic acid with naproxen/ paracetamol/ ibuprofen/ metronidazole/ withtramadol/ with tranexamic acid/ with sertraline/ amoxicillin?

Mefenamic acid may interact with the drugs mentioned above. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be require

Does Nikmef 50mg Syrup make you drowsy?

Nikmef 50mg Syrup has a rare side effect of causing drowsiness. Always consult your doctor, if you experience such side effects.

Fact Box

Chemical Class

Aminobenzoic Acids Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates)

References

Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 854-55.
ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
Mefenamic Acid. 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mgee Healthcare
Address: Khasra no. 101, Dharampur, P.O.Thana Tehsil Baddi Distt. Solan HP 0173205

Vendor Details

Country of origin: India

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Why we need a prescription?

Nikmef 50mg Syrup

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Nikmef Syrup

Benefits of Nikmef Syrup

Side effects of Nikmef Syrup

How to use Nikmef Syrup

How Nikmef Syrup works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

Is mefenamic acid an antibiotic/ contain codeine?

Is Nikmef 50mg Syrup a painkiller?

Is Nikmef 50mg Syrup safe?

Is Nikmef 50mg Syrup good for toothache/ for back pain/ headache?

Does Nikmef 50mg Syrup stop periods/ stop bleeding?

Can I take mefenamic acid with naproxen/ paracetamol/ ibuprofen/ metronidazole/ withtramadol/ with tranexamic acid/ with sertraline/ amoxicillin?

Does Nikmef 50mg Syrup make you drowsy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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